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Doctor insights on: Diffused Lymphoma Patients Symptoms Abnormalities

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Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Maybe: In general we don't think of diffuse large b cell lymphoma (dlbcl) effecting brain function. However, many patients tell us of symptoms of a "fog" like feeling either before treatment (disease-related?) or after ("chemobrain"). Reasons are likely multifactorial and can include stress, financial concerns, depression, and disease biology. This is being actively studied by a variety of groups. ...Read more

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Dr. Michael Thompson
1,747 doctors shared insights

Lymphoma (Definition)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then ...Read more


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Do b symptoms eventually develop in lymphoma? Are there stage 4 patients with no b symptoms?

Do b symptoms eventually develop in lymphoma? Are there stage 4 patients with no b symptoms?

B Symptoms: B symptoms are any combination of persistent fevers, drenching night sweats/chills, or significant weight loss. Not all lymphoma patients get them. Not even all stage IV lymphoma patients get them. Patients without b symptoms and stage IV disease are staged as having stage iva disease. ...Read more

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What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

What is the best way to recover from low WBC after chemotherapy (r-cvp for stage 2 diffuse large b-cell lymphoma) for a very elderly (85y) patient?

It depends.: R-cvp is a relatively milder regimen and therefore it does not usually result in very low wbcs. In general, modest decrease in WBC is expected and is not associated with higher risk for infections unless WBC become very low with neutrophil count below 500. If this is the case, you doctor may decide to use a growth factor given after chemotherapy to stimulate your bone marrow to produced wbcs. ...Read more

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Is beta-2-micro globulin typically elevated in lymphoma patients?

A prognositic factor: levels are incorporated into staging system for multiple myeloma. Higher levels in 75% cases can correlated with higher tumor burden. ...Read more

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If a patient is in critical condition with lymphoma, can it be treated?

If a patient is in critical condition with lymphoma, can it be treated?

Lymphoma treatment: I am assuming by treatment you are referring to chemotherapy. Usually we would like one to be relatively healthy other than the tumor itself, before administering chemotherapy . Therefore in answer to your question, probably not a good idea. ...Read more

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How long can t cell lymphoma patients live?

Many types : There are many types of t cell lymphoma. Some types are very slow growing, treatable but not curable..Patients can live for decades. Other types are much more aggressive. Some are highly treatable and even can be cured while others are quite difficult to get into remission. ...Read more

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Average life span for patients with mantle cell lymphoma?

Average life span for patients with mantle cell lymphoma?

Stage ?: Depends on stage. There are two subsets of mantle cell nhl. One is an indolent subset in which 5 yr survival approaches 70-80%. The othe more aggressive subset has a prognosis of only 50/50 at three years. But stage also matters. ...Read more

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Is ldh always high with lymphoma patients? Any other tests (blood tests)

Is ldh always high with lymphoma patients?  Any other tests (blood tests)

No: Ldh may be high in lymphoma, but may not be. There are many laboratory and other tests used in the initial staging and prognostic testing for lymphoma. Also some tests are used before initial treatment because of concern of viral reactivation -- eg hiv, hepatitis studies. ...Read more

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Lymphoma starts in the immune system. Does that make a patient more prone to everyday illnesses? (colds, flu, etc?)

Probably: Lymphoma, as any other cancer, may be related to decreased immunity from the beginning (decreased immunity is one of the factors favoring the appearance of cancer) or may result in decreasing immunity due to progression of disease. Also, chemotherapy for lymphoma may cause decreased immunity. So yes, these patients are more prone to various infections. ...Read more

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How safe is Rituxan (rituximab) for lymphoma? How about in patients with Cardiac disease?

How safe is Rituxan (rituximab) for lymphoma? How about in patients with Cardiac disease?

Safe: Rituxin is one of the few mAbs that can destroy a tumor by inducing antibody dependent cell cytoxicity (ADCC) by targeting CD20 on the lymphocyte. This surface antigen is present in all lymphocytes including lymphoma. But the lymphocyte population is reestablished every 24hr causing no major side effects. It improved CHOPP survival from 50% to better than 80% without cardiac toxicity. ...Read more

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Review of tonsillar lymphoma in pediatric patients from the pediatric oncology group: what can be learned about some indications for microscopic examination?

Review of tonsillar lymphoma in pediatric patients from the pediatric oncology group: what can be learned about some indications for microscopic examination?

Data says don't: There have been a number of studies (2005 pog study and more recently in 2011 and 2012) to suggest that always doing microscopic examination on routine tonsillectomies is not cost effective. If someone has a index of suspicion (clinical or asymmetric enlargement), then it is warranted. It has been estimated that not doing this automatically could save ~$35 million per year. ...Read more

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Could hydroxyurea therapy cause leukemia and/or lymphoma among patients?

Could hydroxyurea therapy cause leukemia and/or lymphoma among patients?

Possibly: The agent is considered mutagenic and although the risk is low, it is a real one. ...Read more

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How long does a patient have with stage IV non hodgkin lymphoma onchemotherapy ?

Very hopeful: This cancer ios often curable, so we must be very hopeful and do the treatment well so the results will be good. ...Read more

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What is the life expectancy for a CHF patient with hodgkin lymphoma if they are not treated?

What is the life expectancy for a CHF patient with hodgkin lymphoma if they are not treated?

Depends: Hodgkin lymphoma is a highly curable cancer. Severe CHF might limit some of the chemotherapy options, but even in the unusual circumstance that no chemotherapy could be given, cures can still be achieved with radiotherapy alone. Life expectancy for untreated disease depends on a number of factors but is likely to be only about 12 months on average with some doing better and some worse. ...Read more

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Can a patient with lymphoma recover by having a bone marrow transplant?

Can a patient with lymphoma recover by having a bone marrow transplant?

Recover?: What do you mean by recover? A bone marrow or stem cell transplant can be part of the therapy for lymphomas. For some types of lymphoma it can help improve the chances of curing the cancer. It's role is depedent on many factors that would need to be discussed with an oncologist. ...Read more

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