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Doctor insights on: Diffuse Scleroderma

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Does any one out there know about morphea scleroderma?

Does any one out there know about morphea scleroderma?

YES SEE BELOW: Morphea is a medical term for localized scleroderma. The disease involves isolated patches of hardened skin - there generally is no internal organ involvement. ...Read more

Dr. Pierre Moeser
183 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


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What is the difference between limited and diffuse scleroderma?

What is the difference between limited and diffuse scleroderma?

Skin involvement: The differene is the extent of the skin involvement. In the limited scleroderma the skin involvement is restricted to the hands, and to a lesser degree, the neck and face. Patients with diffuse scleroderma has extensive skin sclerosis and high risk for internal organs involvement like affecting the kidneys, heart, and lung. ...Read more

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How csn we differniate between limited and diffuse scleroderma?

See details: It is sometimes very difficult but truly limited disease is generally limited to the skin and has no internal organ involvement, typical hand changes or raynauds. ...Read more

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Is ANA pattern nucleolar with a negative ENA always diffuse scleroderma no symptoms

No: The nucleolar ANA pattern may pop up in a variety of situations, or even fairly low titers in healthy people. And the test is easy to do wrong. This isn't even much of a prediction that you'll develop signs of scleroderma in the future. ...Read more

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Am I a person with diffuse scleroderma if positive ANA 1:40 and 1:160 1 1/2 years ago but negative subtests and no symptoms except episcleritis once?

I don't think so.: Diffuse scleroderma would likely be rapidly progressive, with symmetric skin thickening of extremities, skin and trunk. Visceral involvement is also more likely sooner, like renal and cardiac involvement. Also things like ESR would be elevated. Apparently positive ANA anticentromere pattern would be associated with the limited cutaneous or crest form of scleroderma. See your dr. For more tests. ...Read more

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Could IBS diarrhea form be the only symptom appearing including no skin involvement in diffuse scleroderma meaning no other symptoms but a positive ANA with negative ena?

Quite doubtful.: In scleroderma, sacular diverticuli can form, but this is usually not early. In the absence of raynaud's syndrome, subungual capillary abnormalities (rheumatolgist use a 30x microscope to examine for this), and more specific serologies......I conclude your problem lies elsewhere. ...Read more

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Scared! I had a positive ANA twice 1:40 and 1:160 nucleolar pattern only symptoms have been mild dry eye and one possible episode of episcleritis in the last year. I am scared I have diffuse scleroderma. Been to several rheumatogists and dermatolog

Scared!  I had a positive ANA twice 1:40 and 1:160 nucleolar pattern only symptoms have been mild dry eye and one possible episode of episcleritis in the last year.  I am scared I have diffuse scleroderma.  Been to several rheumatogists and dermatolog

Relax!: Take a deep breath! having a positive ANA doesn't mean that you have a particular disease. In fact lab testing is only a part of the diagnosis, the main part is the clinical picture. Is a good thing to be on top of your health, but being too much can be harmful too. You have already consulted specialists in that area. Follow their recommendations. ...Read more

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In difuuse scleroderma would the only symptom be IBS diarrhea form?

In difuuse scleroderma would the only symptom be IBS diarrhea form?

Similar: In ibs the bowel is normal, just misbehaving. In scleroderma, the bowel is abnormal. Ibs can be cramping, constipation, diarrhea. Scleroderma is usually weight loss due to nutrient malabsorption, diarrhea and bloating due to bacterial overgrowth. Constipation can occur due to lack of intestinal contractions. ...Read more

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What is scleroderma?

Hard skin: Scleroderma literally means "hard skin." it is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown. ...Read more

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Who gets scleroderma?

Anyone,even children: Anyone can get scleroderma, even children. Women have a higher incidence than men. There are different forms of scleroderma and those subtypes vary slightly in their incidences among people of european versus african descent. ...Read more

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What causes scleroderma in people?

What causes scleroderma in people?

I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read more

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How will my scleroderma be treated?

How will my scleroderma be treated?

Please see below: Scleroderma has no cure. But symptoms and damage can be reduced with treatment. ...Read more

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What can I do to treat scleroderma?

What can I do to treat scleroderma?

Depends on type: The treatment ranges from "no treatment necessary" for mild forms of localized scleroderma (limited to the skin) to bone marrow transplantation for systemic sclerosis with internal organ involvement. Though there is no cure, advances are being made in the treatment of all manifestations of the condition. ...Read more

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What are the tests for scleroderma?

Scleroderma tests: The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even offer some predictions as to risks of certain types of complications. Anti rna-polymerase iii antibody, increases risk of renal crisis and sudden increase in blood pressure, antitopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension. ...Read more

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How do people with scleroderma look?

How do people with scleroderma look?

Large range: There are numerous manifestations of scleroderma but the main feature is usually hard skin. This may be thickened hard skin in patches or around just a few fingers +/or toes or around the mouth. Others may have greater involvement of arms, legs causing difficulty moving joints. Worst are disfigurement of face and widespread tight skin over chest, abdomen. ...Read more

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How many people die from scleroderma?

Rare disease: Scleroderma is a very rare autoimmune disease which often results in a progressive decline in health resulting in death, due to the fact that little or no treatment options exist for scleroderma. It is quite rare, among the rarest of all immune complex diseases. ...Read more

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What makes systemic scleroderma flare?

What makes systemic scleroderma flare?

Stress: There are no specific triggers to avoid if you have the condition. However, internal or external stress often precede a flare of scleroderma. ...Read more

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Dr. Mathew Chengot
141 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more