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Doctor insights on: Diffuse Metastatic Disease

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What is metastatic disease?

What is metastatic disease?

Spread of disease: Metastatic is a term used to describe a disease that has spread from its initial point. It is primarily used with regards to tumors that have started to arise at multiple places in the body, most frequently by spreading through the bloodstream. ...Read more

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So what are the early symptoms of metastatic liver disease?

So what are the early symptoms of metastatic liver disease?

Usually nothing: Commonly without symptoms. May cause jaundice or changes in liver tests. Pain rare. ...Read more

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What is sarcoma versus metastatic disease versus lymphoma versus paraganglioma?

What is sarcoma versus metastatic disease versus lymphoma versus paraganglioma?

Different lesions: A sarcoma is a malignant lesion arising from connective and not glandular tissue such as visceral leiomyosarcoma of uterus or stomach. Metastatic disease represents spread of tumor that may arise from a sarcoma or carcinoma, lymphoma is a malignant form of blood cellular disease and paraganglioma is the benign form of the lesion arising from nerve tissue. All represent different forms of disease. ...Read more

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When a pet scan report says "no other evidence of metastatic disease." does that mean there was evidence of it somewhere in the body, but nowhere else?

Metastatic disease: Pet scans are imaging studies that look for subtle signs of increase metabolism in the body. Cancer cells have an increased metabolism compared to regular cells. If there are no spots of increased metabolism beyond where the cancer started then there are no signs of metastatic disease. ...Read more

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How can you differentiate primary malignant bone tumor from metastatic bone disease in x-ray?

How can you differentiate primary malignant bone tumor from metastatic bone disease in x-ray?

Several ways: A primary bone tumor might have certain radiographic characterisitics that are different than metastatic bone disease. Multiple bone tumors strongly suggests metastases. The presence of a prior cancer also strongly suggests that a bone tumor is metastastic. ...Read more

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Metastatic carcinoma in ovaries & in pelvi (peritoneum). Confirmation of Metastatic disease from Ca Gal, Now she has Stage IV. Go for chemo or no.

Metastatic carcinoma in ovaries & in pelvi (peritoneum). Confirmation of Metastatic disease from Ca Gal, Now she has Stage IV. Go for chemo or no.

Don't use of Abbrevi: Your oncologist's advice is best, follow what he/she recommended. Is this a cancer of the Gall Bladder? Your use of abbreviations are misleading me...so do not use them. Tell us the name of her Cancer. ...Read more

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Ct states innumerable tiny and very small pulmonary nodules appreciated. Does this mean metastatic disease?

Nodules in lung: Not all multiple nodules in the lung are cancer. They can sometimes be benign. A repeat scan 2-3 mo later can be helpful in differentiating this dilemma. ...Read more

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Hx breast ca, US spleen meaning? : Multiple hyperechoic solid lesions, indeterminate nature. Hemangiomata possible but metastatic disease not excluded.

Hx breast ca, US spleen meaning? : Multiple hyperechoic solid lesions, indeterminate nature. Hemangiomata possible but metastatic disease not excluded.

Your doc can explain: Your spleen has some shadows which require better imaging than what the Ultrasound produced. Your doctor should guide you further because it will take a CT scan or MRI test/s to provide a more clear picture of what the nature of these shadows in your spleen is. ...Read more

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Can the blood work be normal by having lymphoma or metastatic disease? My blood was ok beside the d dimer which was 1.78. no bl. Clots found in leg/arm

Can the blood work be normal by having lymphoma or metastatic disease? My blood was ok beside the d dimer which was 1.78. no bl. Clots found in leg/arm

Can be normal: Lymphoma is a condition associated with malignant changes in lymphocytes. In order to have elevated serum markers which of themselves are only about 60% accurate in diagnosis, the tumor must contain a tumor antigen on the surface which when shed into the blood is the so called marker. Lymphomas don't have any such marker. Other tumors shed a carbohydrate marker which can rise with inflammation. ...Read more

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Multilobulated pulmonary mass w/calcifications in left upper lobe. Neoplastic disease vs inflammatory/infectious process. Rule out metastatic disease?

Multilobulated pulmonary mass w/calcifications in left upper lobe. Neoplastic disease vs inflammatory/infectious process. Rule out metastatic disease?

In general...: IN GENERAL, a multilobulated mass is more likely malignant, one with calcifications is less likely. As in much else, size matters, with bigger being more worrisome. If you're smoker, more likely malignant, if from place of endemic TB or histoplasmosis, risk of chronic infection rises. You'll need to be evaluated by a pulmonologist, who will very likely recommend biopsy. ...Read more

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Are there any diseases that can cause lesions on multiple organs (liver, brain, pancreas, etc) besides metastatic cancer?

Are there any diseases that can cause lesions on multiple organs (liver, brain, pancreas, etc) besides metastatic cancer?

Lots: Infections such as abscess, parasites, fungus, and amoeba for starters. inflammation of the blood vessels can cause multiple lesions. Certain genetic disorders can affect multiple organs. ...Read more

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Result of CT scan states " findings are mediastinal lymphadenopathy and soft tissue nodules both lungs in all segments (extensive metastatic disease) "?

Result of CT scan states " findings are mediastinal lymphadenopathy and soft tissue nodules both lungs in all segments (extensive metastatic disease) "?

Very concerning...: These findings are extremely concerning and you need to discuss this with your healthcare team. You will likely undergo more tests and referrals to specialists who will provide you more detailed answers than what I am able to do. Do not delay. ...Read more

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Abnormal focal osseous uptakes are identified in the right proximal clavicle and the right scapula with corresponding osteolytic and blastic findings on CT are consistent with metastatic disease. Cancer?

Abnormal focal osseous uptakes are identified in the right proximal clavicle and the right scapula with corresponding osteolytic and blastic findings on CT are consistent with metastatic disease. Cancer?

Correct.: In the absence of long standing prior trauma or metabolic disease history, these findings in an otherwise healthy 66 y/o male would most frequently been seen with bone metastasis. ...Read more

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Can diffuse sclerotic bone metastatic deposits eventually resolve through normal remodeling, assuming cancer stays inactive?

Can diffuse sclerotic bone metastatic deposits eventually resolve through normal remodeling, assuming cancer stays inactive?

No: These do not regress as long as the cancer is there, unless the cancer is overgrown by a tumor with different biology. The cancer creates and maintains the abnormal remodeling that results in the blastic lesion. ...Read more

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Is it possible that adrenal cancer (primary or metastic) cause addisons disease. Can it also cause other adrenal problems?

Is it possible that adrenal cancer (primary or metastic) cause addisons disease. Can it also cause other adrenal problems?

Unlikely.: Involvement of the adrenals with cancer is not likely to cause adrenal insufficiency since most of the adrenal gland would need to be destroyed to produce that. ...Read more

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Can metastic liver tumors or cancer go untreated for 10yrs? Can anything mimick liver disease/cancer besides the gallbladder?

Can metastic liver tumors or cancer go untreated for 10yrs? Can anything mimick liver disease/cancer besides the gallbladder?

An odd: Question. Gall bladder, the organ, or symptoms from its disease, do not mimic liver cancer. A stone in the common bile duct could mimic biliary or pancreastic cancer (pain and jaundice), but none of this can last 10 years. Liver cysts can be their from birth. Mets to liver imply aggressive primary cancer; ergo 10 yr history highly unlikely. ...Read more

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Chances of survival for a 24yo women with a 8.7cm papillary cancer of thyroid with metastic neck disease 13/15 lymph nodes were cancerous.

Chances of survival for a 24yo women with a 8.7cm papillary cancer of thyroid with metastic neck disease 13/15 lymph nodes were cancerous.

100% survival rate: In younger 45, papillary carcinoma with only lymph node spread no distant metastasis, next step is to get all available treatments ...Read more

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Metastic colon cancer. Chemo started in march. Person passed away within 2 weeks of appetite loss and bilirubin increase. Although scan showed stable disease. Can this happen.?

Metastic colon cancer. Chemo started in march. Person passed away within 2 weeks of appetite loss and bilirubin increase. Although scan showed stable disease. Can this happen.?

Yes: While most patients with metastatic colon cancer receiving chemo can function in the advanced stage of disease for 5-7 months, some live only a few weeks after chemo is initiated. This is due to extent of liver and other sites of mets. Although scan showed stable disease, some tumors express TNF and develop cachexia and loss of appetite leading to organ failure and end stage disease. ...Read more

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Can metastic colon cancer cause stage 2 kidney disease?

Can metastic colon cancer cause stage 2 kidney disease?

No: Over a 40 yr. Period I have only seen one colon cancer spread to renal parenchyma. Stage 2 kidney cancer is due to a lesion arising in kidney parenchyma and does not represent metastatic tumor to kidney. The lesion that does spread to kidney and eventually spreads though very rare is adenoCa of lung spead to kidney. If no lung lesion we are essentially talking about a primary kidney tumor ...Read more

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What treatment should you expect with a 8.7cm papillary cancer of the thyroid with metastic neck disease and 13/15 lymph nodes were cancerous?

What treatment should you expect with a 8.7cm papillary cancer of the thyroid with metastic neck disease and 13/15 lymph nodes were cancerous?

Large cancer: 8.7 cm is a very large thyroid cancer. Total thyroid removal followed by treatment with radioactive iodine is needed. If the patient is under 45 years old, the prognosis is still very good. ...Read more

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When given 3 to 6 months prognosis, because of metastic breast cancer that has returned 3 times now to brain, what will the body/disease do as result?

When given 3 to 6 months prognosis, because of metastic breast cancer that has returned 3 times now to brain, what will the body/disease do as result?

It depends: The degree of control of the brain tumor is important. Although it has returned, the question is whether all avenues such as surgery, gamma knife or both have been used to control the brain tumors. With respect to the rest of the body, imaging/staging studies should be done to see how extensive the breast cancer is. That is, has it gone to the liver or lung or bone? That would make a big difference. ...Read more

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Why would a oncologist say "possible" peritoneal disease in a person with metastic colon cancer but the ct report has no Mention of peritonial?

Why would a oncologist say "possible" peritoneal disease in a person with metastic colon cancer but the ct report has no Mention of peritonial?

Not inconsistent: Peritoneal disease from metastatic colon cancer may affect the peritoneal lining in a thin layer, too thin for the resolution of a CT scan. In other words the CT may not be able to detect peritoneal disease. ...Read more