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Doctor insights on: Diffuse Large Cell Lymphoma Symptoms

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Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Do diffused large b cell lymphoma patients show symptoms of mental abnormalities?

Maybe: In general we don't think of diffuse large b cell lymphoma (dlbcl) effecting brain function. However, many patients tell us of symptoms of a "fog" like feeling either before treatment (disease-related?) or after ("chemobrain"). Reasons are likely multifactorial and can include stress, financial concerns, depression, and disease biology. This is being actively studied by a variety of groups. ...Read more

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Dr. Michael Thompson
1,760 doctors shared insights

Lymphoma (Definition)

A malignancy that develops in the lymph glands that causes nodes ...Read more


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Are lymphocyte rich hodgkin's lymphoma and nodular lymphocyte predominant hodgkin's lymphoma the same?

Are lymphocyte rich hodgkin's lymphoma and nodular lymphocyte predominant hodgkin's lymphoma the same?

Sometimes: Both ate classified as hodgkin but they can behave differetlny. Both are treated te same with chemo abvd regimen. Some new data suggest adding Rituxan (rituximab) if cd 20 positive in lymphocyte predominantly disease. ...Read more

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

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Can agent orange cause diffuse large b cell lymphoma?

Can agent orange cause diffuse large b cell lymphoma?

No one knows: Certainly some other cancers have been linked but as far as i know there is no direct linkage. On the other hand, herbicides have had an association with lymphoma and myeloma and agent orange is a "super herbicide". It is always hard to show a direct linkage. ...Read more

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Which is worse, b cell lymphoma or t cell lymphoma?

Which is worse, b cell lymphoma or t cell lymphoma?

T-cell NHL: The prognosis for t-cell non-hodgkin's lymphoma (nhl) vs. B-cell nhl depends on multiple factors, but in general t-cell nhl has a worse prognosis. One reason is that b-cell, cd20+ nhl can be treated with the anti-cd20 monoclonal antibody Rituximab in addition to chemotherapy. We currently don't have such an effective, low toxicity antibody (biologic treatment) for t-cell nhl. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Most common symptoms of cutaneous t cell lymphoma?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:

Itchy skin: Pruritus /itchy skin would be the most common symptoms. Skin manifestation can vary from redness, dryness, lumps, etc. ...Read more

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Is diffused b cell lymphoma genetic?

Not really: While there may be a genetic suscepibiltiy to developing lymphoma it is not truly a genetic disease. ...Read more

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What can cause inhomogenous spleen in hodgkin lymphoma?

What can cause inhomogenous spleen in hodgkin lymphoma?

Lymphoma in spleen: Inhomogenious spleen refer to a ct scan reading where different area of the spleen might have different texture. In general some of these cases are nonspecific, some are related to ifarction (dead tissue) and some are related to lymphoma. In this case, if the patient is already diagnosed with hodgkins lymphoma, most probably these area are lyphoma in the spleen surrounded by normal spleen tissue. ...Read more

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Nhl small lymphocytic \lymphoplasmocytoid-type diffuse large nodulated mass 8.6*6.0*4.5 CM removed surgery appeared again, no chemo 78yrs thin woman?

Nhl small lymphocytic \lymphoplasmocytoid-type diffuse large nodulated mass 8.6*6.0*4.5 CM removed surgery appeared again, no chemo 78yrs thin woman?

Need to consult: A hematologist. The issue you presented is much too complicated for this forum. Please consult your doctor and seek a consultation with a hematologist. ...Read more

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Does early stage small cell lung cancer cause muscle loss and malabsorption or are these later symptoms?

Does early stage small cell lung cancer cause muscle loss and malabsorption or are these later symptoms?

Lung cancer cachexia: Muscle wasting and weight loss ("cancer cachexia") are usually late stage occurrences; malabsorption is usually not the cause of these signs, but rather "hormones" released from the tumor cause a hyper metabolic state and also contribute to poor appetite. If you are already experiencing these problems, however, it is possible that the tumor - although localized (stage 1) is unusually active. ...Read more

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What causes an inhomogeneous spleen in hodgkin lymphoma?

Lymphoma vs. other: The spleen in hl may be heterogeneous/inhomogeneous/non-uniform due to lymphoma involvement, spleen infarction (death) due to cancer death in the spleen, or infection, or "other". The radiologist may or may not be able to determine that and your oncologist might be able to say more about it with knowing the clinical history. ...Read more

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Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?

Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder.  Is this lymphoma?

Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more

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Stage non small cell lung cancer in left lung hilum region and lymph node involvement.

Stage non small cell lung cancer in left lung hilum region and lymph node involvement.

Depends: In order to give exact stage need size of tumor also other wise answer is presumptive lacks accuracy. ...Read more

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What is diffused b cell lymphoma?

Aggressive lymphoma: This is a type which is usually aggressive and can present at an advanced stage. Fortunately, the majority do respond well to modern chemotherapy regimens. A significant number relapse and require more therapy/ transplant. ...Read more

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Lul non small cell hilum region with lymph node involvement on pulmonary artery. Pet scan negative. Please stage.

Lul non small cell hilum region with lymph node involvement on pulmonary artery.  Pet scan negative.  Please stage.

Need more info: To completely stage, would need more information. However, lymph node involvement excluded stage 0 and stage i. If lymph nodes are on the same side as the hilar tumor, the tumor is at least 2 cm from the carina (where trachea divides into r and l main bronchi) and the tumor is 5 cm or smaller, it is stage iia. If tumor is 5-7 cm, and the rest true, it is stage iib. After that, it is complex! ...Read more

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Esophageal mucosal fragments reveal moderate mixed inflammatory cell infiltrate compromising neutrophils, lymphocytes, foci of mild dysplasia. Bad?

Esophageal mucosal fragments reveal moderate mixed inflammatory cell infiltrate compromising neutrophils, lymphocytes,  foci of mild dysplasia. Bad?

Maybe: Please check your report and see if there is any mention of barrett's esophagus or intestinal metaplasia. These findings would indicate a premalignant component that requires regular, lifetime followup. The finding of mild dysplasia may require additional medicines for a while, but please followup with your gastroenterologist that did the biopsy. ...Read more