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Doctor insights on: Diffuse Intrinsic Pontine Glioma

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MRI scan shows two small focal flair hot spots in either frontal lobes subcortically. Mild peri ventricular gliosis. Age related mild diffuse atrophy.

MRI scan shows two small focal flair hot spots in either frontal lobes subcortically. Mild peri ventricular gliosis. Age related mild diffuse atrophy.

Probably not...: ...significant. A few small lesions can be seen in many patients without an underlying problem. If there is any concern, then a repeat MR in 4-6 months can be performed. Without any interval change, then you should not worry. However, atrophy at your age is more worrisome and not common, and your Doctor should examine you closely for any underlying cause. ...Read more

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Dr. Shon Cook
118 doctors shared insights

Astrocytoma (Definition)

Astrocytoma is a tumor that is arising from a specific cell type in the central nervous system (brain or spine) that is called astrocyte. These are the cells that support the actual nerve cells (neurons). It is a common type of nervous system tumor, which has different types, benign to malignant. Treatment is tailored according to this as well ...Read more


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S+s of end stage primary brain cancer, (aa iii) r medial temporal lobe, diffuse numerous cells. Growing!/brainstem and posterior temp./basal ganglia?

S+s of end stage primary brain cancer, (aa iii) r medial temporal lobe, diffuse numerous cells. Growing!/brainstem and posterior temp./basal ganglia?

Ask for more info: Signs and symptoms can vary greatly with any 'end-stage' cancer. Things like if it has spread to other organs, impacting functional status and alertness (sleeping more, in bed most of the time), causing pain/seizures, and so on. His doctors can maybe determine what is most likely. If not involved already ask for hospice or palliative care help as they could also help answer what the s/s might be. ...Read more

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My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

Small vessel disease: Mri in a 84 years old lady showing infarcts and small vessel disease means she is having ministrokes. That is very common in that age group. If she has heart disease or carotid artery disease or risk factors like high BP or diabetes or high lipids they should be controlled and she should follow up with her dr who can give her further recommendations. ...Read more

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MRI brain results Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?

MRI brain results  Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?

Covering the bases: That signal that is seen in patients who age is seen very frequently. Most of the time it is what has become known as microangiopathic disease or small vessel disease. Demyelination and gliosis come with a more notable history. Gliosis or scarring and demyelination also produces symptoms that MRI is useful for. Depends on why you had the MRI in the first place. The first entity more common than 2 ...Read more

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38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

Nothing to cure: But try to prevent further damage. Maxillary sinus polyp is nothing to worry about unless sinus symptoms, then ENT consult. Partial empty sella cannot be fixed, and nothing to worry about unless abnormal pituitary function - may need to see an endocrinologist. Ischemic lesions may be within normal limits (allowed 1 per decade of life), but need to understand cause(s) and try to prevent more. ...Read more

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Had MRI of brain. States diffuse pathologic t2 hypersignall noted bilaterally in frontal parietal regions. I'm scared....Dementia? ? Ms???

Had MRI of brain. States diffuse pathologic t2 hypersignall noted bilaterally in frontal parietal regions. I'm scared....Dementia? ? Ms???

Discuss w/ provider: One of the most important parts of imaging is providing meaningful and clear explanations of results to the patient and their family. There is no need for you to suffer additional hrm from being scared. Don't wait - call for a followup visit ASAP. Meanwhile - stop trying to guess at the meaning. It takes doctors years to understand these results. You'll Best! ...Read more

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What is diffuse fibrillary astrocytoma?

What is diffuse fibrillary astrocytoma?

Astrocytoma: You are asking about a tumor of the brain that arises from one of the support cells within the brain - diffuse means it is widely spread and the tumor is normal benign but can be more involved depending on the location and the size ...Read more

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Please explain: renal cortex contains 29 glomeruli, 13 of which are globally sclerosed. There is focal segmental mesangial hypercellularity.

Please explain: renal cortex contains 29 glomeruli, 13 of which 
are globally sclerosed. There is focal segmental mesangial 
hypercellularity.

Sclerosis: So Glomeruli are Filteration units of Kidney. Since kidney's main function is Filteration; the health of glome is directly related to renal function. Sclerosis in layman term means scarring. So 13/29 glomes are scarred. Which means approximately 50% of functional units are scarred or non functional. Mesengial hypercellularity refers to the inflammation in the kidney. Very common with FSGS ...Read more

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F,48. Pls detail(1)"nonspec hyperintense FLAIR foci involving L.parietal+bilateral.frontal.lobes" +(2)"signal void along main intracranial vasculature?

F,48. Pls detail(1)"nonspec hyperintense FLAIR foci involving L.parietal+bilateral.frontal.lobes" +(2)"signal void along main intracranial vasculature?

Radiology terms: This is specialized radiology terminology and isn't helpful by itself. The radiologist should provide a conclusion at end of report as to what it all means. This must then be interpreted in context of what symptoms led to study in first place. Too much for any of us to answer in this format. Talk to the doctor who ordered the study. Good luck. ...Read more

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Is central pontine mylinosis serious?

Is central pontine mylinosis serious?

Yes: Now called "osmotic demyelination syndrome", it is a neurological disease caused by severe damage of the myelin sheath of nerve cells in the brainstem and sometimes outside the brainstem. It can be caused by rapid correction of low serum sodium. Less commonly, it may also present in patients with a history of chronic alcoholism or other conditions related to decreased liver function. ...Read more

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Result for my brain MRI -asymmetric decreased attenuation in the left basal ganglia, variant dilated perivascular spaces or punctate chronic lacune. ?

Result for my brain MRI -asymmetric decreased attenuation in the left basal ganglia, variant dilated perivascular spaces or punctate chronic lacune.  ?

MRI report: This is language used in radiology to describe what they see. Ordinarily, they cannot distinguish a small stroke (lacune) from a perivascular space. A "puntate lacune" though is very small. It is probably just the side view of a blood vessel (aka perivascular). Do you smoke? Do you have high blood pressure? Do you have diabetes mellitus? Atrial fibrillation? These are stroke risk factors. ...Read more

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My MRI brain show coalescing granulomata measur 8x 4 mm abutting the cuneus rt side. Neuro told likely neurocysticircosis in dgnrative stag pl adv.

My MRI brain show   coalescing  granulomata measur 8x 4 mm abutting the cuneus rt side. Neuro told likely neurocysticircosis in dgnrative stag pl adv.

Cystercercosis: If you do have an infection with taenia solium, or the pork tapeworm, you might be able to confirm with stool samples which may contain eggs. Since you have a lesion already documented, this does raise a risk of potential seizure activity, and you should discuss with your doctor whether or not it is wise to go on anti-epileptic drug. ...Read more

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Age 23. Coma patient. Diffused axonal injury. Intraventricular hemmorhage. Bleeding in frontal lobe. Chances of survival? Any possible impairment?

Age 23. Coma patient. Diffused axonal injury. Intraventricular hemmorhage. Bleeding in frontal lobe. Chances of survival?  Any possible impairment?

Not good : Sorry about this one, but there will be a suboptimal outcome at best. Survival may be issue, talk to your doctors, and perhaps an eeg can guide decisions, but hard to predict outcome of comas. Sounds like a profound traumatic event, and since young and severe, have a family conference with the treatment team, and get all your questions answered. ...Read more

Dr. Jeffrey Buchsbaum
848 doctors shared insights

Glioma (Definition)

A tumor or neoplasm of the glial, non nerve ...Read more