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Doctor insights on: Differin And Clindamycin

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Side effects from using differin (adapalene) & clindamycin phosphate for acne?

Side effects from using differin (adapalene) & clindamycin phosphate for acne?

Not much.: Most commonly feel dry, irrtating and itchy and see peeling, but not everybody. I would not categorize them as side effects. They are natural consequences of using the medicines. ...Read more

Clindamycin (Definition)

Part of the lincoside family. It has good gram positive an anaerobic coverage, but its association with the development of clostridium difficile infection has limited its use. It is used in certain drug allergy situations where staph, strep, pneumococcal, and anaerobic organisms. Its use in MRSA infections is spotty. It is a bacteriostatic drug that works ...Read more


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Is it possible that adapalene + clindamycin phosphate gel deriva c be used only in mornings?

Less effective: The produce when used at night has better absorption and less interaction with sunlight. ...Read more

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My Adapalene gel and Clindamycin Phosphate gel both expired January 2014, can I still use them?

Acne: Not that it would cause harm, but it might lose its effectiveness. You should get a new one. ...Read more

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Adapalene n clindamycin are not treatments for pigmentation left by acne? I have pigmentation! Acne are hardly 2 or 3..

Adapalene n clindamycin are not treatments for pigmentation left by acne? I have pigmentation! Acne are hardly 2 or 3..

Hydroquinone: Pigmentation left behind by acne will not respond to acne creams like Adapalene or clindamycin. Lightening creams containing hydroquinone are available otc and by prescription, but insurance does not cover them - and never use them at concentrations higher than 4% - higher concentrations sometimes make the darkening worse. ...Read more

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Is it better to use benzoyl and clindamycin or adapalene gel for treating acne? Which one of these 2 is more effective and less harmless

Is it better to use benzoyl and clindamycin or adapalene gel for treating acne? Which one of these 2 is more effective and less harmless

Why not both: There is certainly no reason not to use both of them 1 in the morning and one in the night, unless you get to dry period start one first use it for 2 or 3 weeks and then if you have no problem you can start the other one every other night and if you tolerate it advance tonightly. ...Read more

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I am using clindamycin gel with adapalene and orally azithromyc will it erase facial marks left out from acne? Or should I take up laser as a treatmen

I am using clindamycin gel with adapalene and orally azithromyc will it erase facial marks left out from acne? Or should I take up laser as a treatmen

Acne scars: Acne medications may help improve the red or dark marks left by acne spots. They don't do anything for skin texture changes due to scarring. If your acne is still ongoing, laser treatment of scars may actually cause more breakouts. Also squeezing or scratching acne spots can lead to more hyperpigmentation of the skin. There are acne meds like Azelaic Acid gel that may help lighten dark spots, too. ...Read more

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When pregnant is topical clindamycin phosphate 1% ok? Topical differin (adapalene)?

Yes: Most topical medications are not absorbed in enough amount to affect a fetus. That said, these two are ok during pregnancy. ...Read more

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Are topical clindamycin phosphate 1% & differin (adapalene) safe to use whil pregnant?

Would not recommend: It would be advisable to stay away from any form of Retin-A retinol differin (adapalene) or Avage during pregnancy. ...Read more

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Hi doc, ive been using tretinoin - stieva-a for a month now, do u think it will be safe if I change it to adapalene plus clindamycin?

Hi doc, ive been using tretinoin - stieva-a for a month now, do u think it will be safe if I change it to adapalene plus clindamycin?

Yes: Both tretinoin and adapalene are in the same class of medications ("retinoids") with similar side effects (redness, peeling) that vary with dose strength. Changing should be safe. ...Read more

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Can adapalene + clindamycin phosphate gel deriva c get rid of scars?

No: Clindamycin is an antibiotic no scar aide.Adapalene is a Retin-A derative that will control acne and help reduce fine wrinkles. The effects on scars will be minimal at best.
Scars require deep therapy such as fractionated co2 lasers, resurfacing lasers and deep chemical peels applied by properly trained physicians ...Read more

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While pregnant is it safe to use clindamycin phosphate 2% topically? Is topical differin (adapalene) safe while pregnant?

While pregnant is it safe to use clindamycin phosphate 2% topically? Is topical differin (adapalene) safe while pregnant?

It is safe.: Yes. It is safe to use Clindamycin topical. It is also safe to use differin (adapalene), (adapalene) even though drug info suggests "precautious, category-c for pregnancy". Just use common sense, how likely it would be that differin (adapalene) being absorbed through skin and causing systemic (side) effect? None ever reported. ...Read more

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How effective use of adapalene and clindamycin gel to pimples.? Which routine should be prefer for using? And after what time I wash the face?

How effective use of adapalene and clindamycin gel to pimples.? Which routine should be prefer for using? And after what time I wash the face?

Depends. Also: Don't wash your face with body soap. Also don't use alcohol or comedogenic products on your face. Try to find an acne wash system like neutrogena, pangea organics or something with benzoyl peroxide. Following low sodium diet might help too, since acne-causing bacteria like salt. You can try to prevent spreading bacteria onto your face by not touching your face, washing your phone, etc. ...Read more

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What are the treatment options for resistant white head acne? It does not go away with adapalene plus clindamycin combination cream (derviva cms gel)

What are the treatment options for resistant white head acne? It does not go away with adapalene plus clindamycin combination cream (derviva cms gel)

Stubborn Condition: Hello,
you have so many options. It's just difficult to navigate through the marketing mayhem of the 21st century. The best approach is to find someone you REALLY trust who is passionate about resistant acne and is not willing to let you slip through the cracks. It's this level of tenacity, creativity, and care that is ofter the make or break ingredient when treating chronic conditions. ...Read more

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How to use adapalene and clindamycin phosphate gel for acne?

How to use adapalene and clindamycin phosphate gel for acne?

Adapalene: Apply a small amount at bedtime to entire area of acne. Not eyelids or lips OK to skip some nights if irritation. Do you have. 1%? . 3%? With prolonged use it is better tolerated and more effective. Clindamycin may be a waste of money. Benzoyl peroxide OTC is cheaper and more effective. Use a tiny amount in AM. OK to use moisturizer if dry skin. Keep off colored fabrics: will bleach colors.. ...Read more

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How does adapalene and clindamycin phosphate gel work on acne/?

Several ways: Adapalene suppresses the sebaceous glands that nourish the bacteria, and Clindamycin suppresses the bacteria themselves. There's additional minor mechanisms. ...Read more

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How to use and how effective is adapalene and clindamycin phosphate gel for mild acne?

How to use and how effective is adapalene and clindamycin phosphate gel for mild acne?

Take as directed: Both adapalene & clindamycin are approved for use to treat acne. There are many options available so work closely w/your Family Doc & Dermatologist. Check out https://www. Aad. Org/public/diseases/acne-and-rosacea/acne & http://www. Mayoclinic. Org/diseases-conditions/acne/basics/treatment/con-20020580 for more info. ...Read more

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I am using adapalene microsheres + clindamycin phospate gel for treating acne...Does it reduce the black spots....If not what is the treatment for that?

I am using adapalene microsheres + clindamycin phospate gel for treating acne...Does it reduce the black spots....If not what is the treatment for that?

No Rx for dark spots: You can try bleaching them with a hydroquinone-containing solution but don't overdo it. They fade with time. I hope you are able to manage your acne long-term with medication -- it sounds like you're off to a good start. Best wishes. ...Read more

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I have a red skin rash (non painful) right above my lip after 2 weeks of using clindamycin and adapalene should I stop using them or will it go away?

I have a red skin rash (non painful) right above my lip after 2 weeks of using clindamycin and adapalene should I stop using them or will it go away?

Irritation: It is possible that the cream is irritating your skin. You may be using it too generously. Stop using it until the rash goes away. You can started again and see if the rash comes back. You should not be able to see or feel the cream on your skin after you rub it in. ...Read more

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I have been applying clindamycin phosphate gel USP and microspheres adapalene gel for the pimples and scars on my face since a long time. Is that fine?

Good start: It will not touch the scars, and if you do not have full relief, add topical benzoyl peroxide, a systemic antibiotic, or conisder one of the big guns that only a dermatologist can prescribe. If you acne scars are relatively mild, consider keeping them -- several hollywood male leads have done this to "look tough." glad you are getting treated. ...Read more

Dr. Andrew Seibert
138 Doctors shared insights

Adapalene (Definition)

Adapalene is an acne agent which is a ...Read more


Dr. Gary Pess
143 Doctors shared insights

Differin (Definition)

Differin is an acne agent which is a ...Read more