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Doctor insights on: Different Types Of Antihistamines

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Is it ok to take three different antihistamines?

Is it ok to take three different antihistamines?

Not a good idea: Unless specifically instructed by an allergist. I have only seen people on more than one antihistamine for severe recurrent hives (urticaria). Taking too many antihistamines at once can cause issues with urinary retention and other problems. ...Read more

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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Is doxepin a type 2 antihistamine?

Is doxepin a type 2 antihistamine?

Strong antihistamine: Doxepin is an effective but sedating tricyclic antidepressant. This drug's sedating effect is significantly due to its powerful antihistamine effects. Most recently it has been marketed at lower dosages as a sleep medication. ...Read more

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Is it safe to take two types of antihistamines togeather ?

Is it safe to take two types of antihistamines togeather ?

Probably not: It is not a good idea because of the increased risk of side effects from taking multiple similar meds. ...Read more

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If I have an allergy to one antihistamine, is it more likely to also be allergic to another? Even though they r different chemicals?

If I have an allergy to one antihistamine, is it more likely to also be allergic to another? Even though they r different chemicals?

Not necessarily: Most people will tolerate a different antihistamine even if they had a reaction to another. The exception might be antihistamines such as zyrtec and xyzal (levocetirizine) which are closely related. ...Read more

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How many weeks does it take for claritin (loratadine) 10mg to work? How long should I give it a try before deciding to switch to a different antihistamine?

A few hours: Claritin (loratadine) should start working within a couple of hours. If it doesn't not help at all, then switching to another won't do you much good. If it does help somewhat, then you may try the other alternatives which may possess more antihistamine effect than Claritin (loratadine). ...Read more

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Is it OK to take multiple types of antihistamines within a 24-hour period? Nothing seems to work as long as advertised.

Is it OK to take multiple types of antihistamines within a 24-hour period? Nothing seems to work as long as advertised.

DETAILS?????: What are you treating? Which antihistamines? How many of each? There are easy answers after the details are given. No answer is possible without this information. For chronic urticaria I may manage it with 10 or 20mg cetirizine (Zyrtec) in AM and hydroxyzine at bedtime. I never use Benadryl (diphenhydramine) except as a sleeping pill. ...Read more

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Is it possible to be allergic to all antihistamines (hives)? I see hives 90mins after taking 3 different antihit's on different days.

See a dermatologist: Why taking antihistamine? When you see the dr be prepared to name all antihistamines tried. Exact names. It is possible but very unlikely to get hives from antihistamines: they are used to stop hives. ...Read more

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Do the antihistamine nose sprays and the steroid sprays lose their effectiveness over time? Should I alternate, using one type of spray each month?

Should not: These sprays should not lose their effectiveness over time. Some people need both in combination. I would suggest using the antihistamine spray and adding in the steroid spray when your symptoms are not controlled. It may take a couple of days to feel the full effect of the steroid spray. ...Read more

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Dr. Paul Carter
601 doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more