Doctor insights on:
Difference Between Taxol And Taxotere
Same class,diff drug: Both taxol (paclitaxel) and taxotere (docetaxol) are of the class of cytotoxic chemotherapy drugs known as taxanes. They are different chemicals with different pharmacokinetics and side effect profiles but tend to be used in the same disease areas. There is much debate as to whether one or the other is "better" or "more effective" in a certain disease. ...Read more
Chemo: Dose-dense chemo given every 14 days instead 21. You should discuss with the doctor the reasons for offering it, could be a few. ...Read more
Side effects vary: Gemzar is generally well tolerated given weekly 2 out of 3 or 3 out of 4 weeks per cycle. Usually does not cause hair loss or neuropathy. Taxol can be given weekly or every 3 weeks and with risk of reactions during infusion (steroid premedication needed), some hair loss and significant neuropathy. ...Read moreSee 1 more doctor answer
Less neuropathy: Unlike taxol, gemcitabine does not cause neuropathy. It can cause low platelets. It can also cause fluid retention. Also it is usually given 2 weeks on and 1 week off. Unlike taxol which typically is given weekly. That is about it in regards to the difference. Hope this helps. ...Read moreSee 1 more doctor answer
Gem for taxotere: Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read moreSee 1 more doctor answer
Stops cell division: Taxol is a chemotherapeutic agent that act to arrest rapidly dividing cells such as cancer cells. As such, it can also impede certain "normal" cell division such as white blood cels. Cell counts must be monitored frequently during treatment with this agent. ...Read moreSee 1 more doctor answer
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