Doctor insights on:
Difference Between Renal Prerenal And Postrenal Pathology
The basics: Patient identifying data, site from which the tissue was taken, a description of what was received by the pathologist and if so what type of preservative / fixative if any. On resected specimens, the description showcases the pathologist's sharp eyes. Almost always there will be a microscopic description of some portion stained in some way, unless it's orthopedic hardware or something similar. ...Read moreSee 1 more doctor answer
What is necrosis in reference to renal cancer and would it be clearly stated on a pathology report as the percentage of sarcomatiod is?
Dying cells: Necrosis refers to part of the tumor that is dying, presumably because the tumor is growing too rapidly. There is some evidence to suggest that necrosis indicates a worse prognosis although it is not yet included in the required reporting. However if a procedure called embolization is performed to cut off blood flow to the tumor, this type of necrosis is not necessarily bad. ...Read moreSee 3 more doctor answers
After nephrectomy for clear cell renal cancer, pathology lab gave me slides of cancer. How can they be helpful for me in screening/prognosis?
Screening/prognosis: Having your slides with you are always helpful. You are young, and rcc is rare in young people except those with familial predispositions, such as von hippel lindau, polycystic kidney disease or tuberous sclerosis. In terms of screening, your slides can be used by pathologists to compare your prior tumor to anything new that arises or assess the grade of your tumor to prognosticate behavior. ...Read moreSee 2 more doctor answers
Can a person survive prerenal acute renal failure due to severe dehydration without medical help? If so, what are the consequences of not gettin help?
Not advised: Yes, but just because something can be done means that it should be down. A prolonged prerenal state can lead to severe tubular necrosis which is not quickly or always 100% reversible. Prolonged renal failure (prerenal or otherwise) if severe enough puts the individual at risk of death from chemical abnormalities and uremia. Short term risk death, if survives long term risk incomplete recovery. ...Read moreSee 1 more doctor answer
Hoping you can tell me, is common predisposing factor for pre-renal acute renal failure post-operatively?
Does urine specific gravity increase or decrease in post-renal azotemia? And what about pre renal?
Depends: In pre renal azotemia if due dehydration or volume depletion, specific gravity should be high but depends on baseline kidney functions like any underlying kidney disease. I am not sure what you meant by post renal azotemia- in general someone passing lots of urine and is clear, specific gravity should be low as it is likely to be dilute urine; but are some exceptions. ...Read more
Pre-renal acute renal failure may occur without systemic hypotension in patients taking nsaid or acei, why? I just do not get it?
Effect blood flow: Nsaids interfere with prostaglandin production in the kidney, some of which may cause blood vessels to dilate. Blocking the prostaglandin production causes the vessels to constrict and decreases blood flow to the kidney. Acei inhibit angiotensin ii production this allows the efferent arteriole to dilate, lowering the hydrostatic pressure in the glomerulous and decreasing kidney function. ...Read more
Different cell type: SCCa is squamous cell carcinoma. This tumor arises from squamous epithelium which can normally be found in many places including the skin, esophagus, cervix, vagina, larynx/vocal cords, and other places. Lymphoma is a neoplasm deriving from lymphoid cells in the lymph nodes or in organs with lymphoid tissue (spleen, tonsils, intestinal tract, etc). SCCa and lymphoma arise from different cells ...Read more
What is the difference between a pathologist/epidemiologist and a biomedical scientist involved in pathology?
Pathologist: A pathologist is a person who has gone to medical school (a physician) and then completed a residency program in pathology. A biomedical scientist would likely have a Phd and trained in a graduate program, not a medial school. Some medical schools do have Phd programs and this can confuse things. :) ...Read more
Color of cells: The cells in an eosinophilic chromophobe carcinoma have a pink color under the microscope instead of the clear look of a typical chromophobe. A pathologist might make the distinction to differentiate it from an oncocytoma, which also has pink cells. Eosin is a stain we use to color the tissue for microscopic examination. In this case, eosinophilic = pink. ...Read moreSee 1 more doctor answer
The time duration: Chronic renal failure, or chronic kidney disease as it is now referred to, is kidney damage or reduction in kidney function that persists for 3 or more months. Anything less than that duration is "acute". These definitions apply regardless of the cause of kidney disease. ...Read moreSee 1 more doctor answer
Renal failure: Acute renal failure: seen in a healthy person who develops an illness (e.g. hemolytic uremic syndrome [in children] or septic shock and multiple organ dysfunction) that leads to renal failure. Often it resolves. End-stage renal disease implies that the problem has been there for weeks/months, is not going to resolve and the person may need kidney transplant ...Read more
Sugar in the urine: Same thing.Get a more detailed answer ›
Interchangeable term: They are all used interchangeably. They all suggest kidney disease (the reasons for which can be many). ...Read more
They are the same: I think that you want the difference between the glycosuria of diabetes mellitus (spilling glucose due to hyperglycemia) and spilling glucose due to the inabilitiy of the kidney to completely reabsorb filtered glucose in someone with euglycemia. The first is high glucose overpowering the reabsorbtion, the second is from weak reabsorbtion. The second is probably harmless, the first is a bad disease. ...Read more
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