Doctor insights on:
Difference Between Novolog And Novolin
Not much!: Humulin n and novolin n are both forms of nph insulin. Nph Insulin is considered intermediate-acting (generally less than 24 hours in duration, usually 8-12 hours). They are both heavily crystallized solutions of human insulin, which is what gives it the longer-acting property (and cloudy appearance) . Humulin is made by eli lilly & co. (usa), and novolin is made by novo nordisk (denmark). ...Read more
Big difference: Novolin has become synonimus with nph novolin insulin, though novolin is just a brand name, you also have novolin regular Insulin or novolin-r, so you have to be careful. Novolog 70 /30 is a combination of 70% nph and 30% NovoLog (fast acting insulin) therefore the action of both insulins is very different. ...Read more
2 comps; unit = unit: They are virtually same insulins made by 2 different companies and they do pretty much exactly the same thing, unit for unit. Novolin n/r or combo of two as 70/30 (70%n, 30%r--r =regular, fast acting, n=normal, longer acting). Humalin n/r or combo 70/30...So for all practical purposes, these two insulins are interchangeable. Consult doc if have concerns. Good luck. ...Read more
Novolog is faster: The '70' portion of both is same, but the '30' portion of NovoLog has faster onset of action <15 min vs about 30 min for novolin (insulin). Otherwise, unit for unit they are about same. The NovoLog thus can be used right before meal, novolin (insulin) should be about 15-30 min before meal. So just timing is different. Consult doc. Good luck. ...Read more
Different timing: R is usually given about 1/2 hr prior to a meal. No longer the short acting Insulin of choice because others more effective having shorter 1/2 lives. Nph may be combined with short acting Insulin or given alone to provide later coverage. Starts to peak in ~ 4 hrs, though effect will last for several. It peaks which predisposes people to low sugars. Newer insulins replace nph for better control. ...Read more
Humulin: Humulin is the marketed name by Eli Lilly and Company. Both are biosynthetic human insulin. Humulin N, is neutral protamine hagedorn (NPH), an intermediate-acting insulin, has an onset of 1-3 hours, peak of 8 hours and duration of 12 to 16 hours. Humulin R is Regular insulin, a short-acting insulin, has an onset of 30 to 60 minutes, a peak of 2-4 hours, and a duration of 5-8 hours. ...Read more
Novolog is faster: The '70' portion of both is same, but the '30' portion of NovoLog has faster onset of action <15 min vs about 30 min for novolin (insulin)/humulin. Otherwise, unit for unit they are about same. The NovoLog thus can be used right before meal, novolin (insulin) should be about 15-30 min before meal. So just timing is different. Consult doc. Good luck. ...Read more
What are the differences between apidra (insulin glulisine) and novolog insulin? Which is better?
Insulin analogs: Hi. Novolog (aspart) and Apidra (insulin glulisine) (glulisine) are both engineered insulins not found in nature. The human insulin gene was modified to give the expressed insulin analog favorable properties for meal coverage for diabetics. To me they are indistinguishable, but Apidra (insulin glulisine) works a little faster in obese patients. They are both very good meal insulins. Goo luck, and keep your diabetes tightly controlled! ...Read more
Onset/duration: Novolin n (a brand of nph) is an intermediate acting insulin. It starts working after a few hrs, peaks in 6-8 hrs and lasts 12-16 hrs. Novolog is a rapid acting insulin. It starts to work in a few mins, peaks in an hr or two, lasts 4 hrs or so. Novolog is used @meals to prevent post-meal high bs and to "correct" bs. Nph (or better yet a long acting like Lantus (insulin glargine) or levemir) keeps fasting bs lower. ...Read moreSee 1 more doctor answer
Both biosynthetic : Novolog and Novolin R are both meal time insulins. Novolog can injected before or immediately after meals, while Novolin R must be at least 30 minutes before meals.Novolin n is as basal insulin. Novolog has a quickest onset, shortest duration of action, least absorption variability, and reduces chances of low blood sugar( hypoglycemia) if used right compared to Novolin R and n respectively. ...Read more
Time course: Hi. NPH & R differ by their time course of action. While they are both now mostly relegated to the history books, some people still use them. R peaks sooner and lasts a shorter time than NPH. Engineered insulins (e.g., Lantus (insulin glargine) vs. Humalog or Novolog) also differ in the time course of action. This gives rise to the notion of "basal" insulin and "meal" insulin. Different insulins fulfill diff. needs. ...Read more
Different categories: Novolin is the brand name given to all human insulins made by novo nordisk. Under this brand are specific types of Insulin such as regular, nph, and 70/30. Novolog Insulin is a synthetic recombinant Insulin that is very rapid acting. I often get this question because NovoLog is more expensive than any of the novolins. However, they cannot be substituted for each other. ...Read more
Same: No difference.Get a more detailed answer ›
Same family: Hi. Glyburide is a second generation sulfonylurea and glimepiride is a 3rd generation. They work at the same receptors on the beta cell (the pancreatic cells that make insulin) and stimulate insulin release. Glimepiride is preferable because of less metabolite build up in kidney disease, but they're VERY similar. I never use them. In my opinion, based on good science, we have much better drugs. ...Read more
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