Doctor insights on:
Difference Between Lupus And Scleroderma
Mixed Picture: It would be very rare (but not impossible) to truly have both diseases together. It would be more likely to develop a so-called "overlap syndrome" in which you have a single autoimmune disorder that seems to borrow some features from each of these classic diseases without truly being purely one or purely the other. ...Read more
It depends: There are several different symptoms that can appear, but it all depends on the patient. ...Read more
Malar rash: Some common early symptoms are a malar or. ...Read more
Ana positive1.810 with a homogenous pattern what does this mean? What could I have? Few family members have lupus 1 scleroderma
See below: Your doctor will have to interpret the ANA in context to your symptoms. With you having a family history of autoimmune disease, you are at increased risk for developing one. However; false positive ANA can occur and we also know that a person who has family history of autoimmune disease may test positive for ana, but may never develop an autoimmune disease. It would be best to see a rheum dr. ...Read more
I have lupus and scleroderma and now I'm being tested for osteonucrosis but it doesn't explain the pain I have everyday in my head, neck and back.
See ortho: I presume you are already under the care of a rheumatologist. If you cannot get an answer from him, either get a 2nd opinion or consult an orthopedist. Having autoimmune disorders does not preclude you from getting the usually bone issues. ...Read more
Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more
See below: There is has been much on how exactly it works but it is thought to work on tlrs or toll-like receptors which play a role in the immune system. ...Read more
Would scleroderma or lupus only affect the vulva nothing else biopsy showed general inflammation?
No: That is not possible.Get a more detailed answer ›
Do you think all connective tissue diseases (lupus, sjogrens, scleroderma) are more alike than doctors realize since they tend to overlap so much?
Related: Autoimmune disease such as lupus and Sjögren's syndrome are indeed related by the fact that it is the immune system that is attacking the body itself. However, different disease have different but overlapping targets of the misguided immune attack. For example, there can be joint pain in lupus, a symptom that overlaps with rheumatoid arthritis. However, the joint involvements are different. ...Read more
I have a positive ANA 1:640 homogenous nuclear staining. Does this mean scleroderma or lupus? I also have a very slightly elevated angiotensin conv en
Depends: No diagnosis can be firmly established with a single blood test even in your case. Bone pain is not the usual manifestation of an autoimmune disease. Why was the test ordered in the first place? If your doctor suspects the presence of an autoimmune disorder, more tests will be needed to pin down the diagnosis. ...Read more
I have lupus- diagnosed w/labs and symptoms. But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!
Rheumatologist.. ..: You need to see a rheumatologist to sort out the lupus question. Lots of symptoms but zero lab evidence may not necessarily be lupus. Make sure diagnosis is right! ...Read more
The Mighty Vitamin D: You may do better in warmer climate closer tot he equator for 2 reasons: more vitamin D and more exercise. Receiving more sunlight would naturally raise your vitamin D levels. Adequate vitamin D is essential for fibromyalgia relief, and is a powerful anti-inflammatory. More exercise, especially light walking or yoga on the beach would add to the benefit of vitamin D. ...Read more
Pos ANA 1:640 homogenous nuclear staining. Normal C3 and c4. What is going on? Most likely lupus? Scleroderma? Had slightly elevated ACE test.
I have bad health anxiety and I have lupus, my close relative just got diagnosed with raynauds at 55 now im worried she has scleroderma, please help?
I have 1 very small telangiectasia on the top of my hand. I have lupus. Does this mean I could have scleroderma or crest too? I'm very fair skinned
No: No it does not. That question is best addressed to your own rheumatologist. ...Read more
Does family history in first cousin (or other NON-first-degree relatives) increase risk for autoimmune diseases such as lupus, scleroderma, RA?
If you have autoimmune disease in your family - you are at increase risk to also develop
Autoimmune diseases also seem to have a genetic component, but, mysteriously, they can cluster in families as different illnesses. For example, a mother may have lupus erythematosus; her daughter, diabetes; her grandmother, rheumatoid arthritis. Research is shedding light on genetic, as well as hormonal and environmental risk factors that contribute to the causes of these diseases. ...Read more
Can u have scleroderma without raynauds? I have HORRIBLE Gerd, for past 4 months with no relief with PPI's, I have lupus I don't want another AI disease
Mom just developed raynauds at age 52 what's chances of her getting scleroderma? No other symptoms, has negative ANA, I am her daughter tho & have lupus
ANA was 1:320, nuclear coarse speckled. Anti-RNP 1.3. Likely scleroderma or MCTD or lupus? Only chest pain and mild acid reflux. 28 female.
The diagnosis of: Connective tissue disorders is tricky and mainly clinical. Antibodies help in the classification but lupus, scleroderma and MCTD are all diseases with a spectrum of clinical manifestations. Many people meet criteria for more than one autoimmune disease. Treatment typically involves biological agents, steroids, and other immunosuppressants. Ask your rheumatologist what your specific diagnosis is. ...Read more
I had ANA 1:160+, ESR 29 CRP 0.1 autoantibodies show ssa of 8 (0-40 is neg) and scl-70 ENA ab of 3 (0-40 is neg) wouldn't this be scleroderma? Not lupus? Why would lupus patient have scl-70 markers?
Not just antibodies: If the scl-70 titer is 3, as you wrote, it falls within the normal range and is not positive. More importantly, scleroderma is not diagnosed on the basis of antibody studies, but rather clinical findings such as skin thickening, raynaud's phenomenon, lung fibrosis, or pulmonary hypertension. A certain percentage of scleroderma patients are even negative for ana. ...Read more
Can telangiectasia be also a symptoms of lupus not just scleroderma? I have 3 tiny red dots on the back of my hand scared of sclero- I have lupus. I am very pale so maybe its not even telangiectasia?
Highly unlikely.: The amount of telangiectasias in connective tissue disease such as scleroderma is usually significant and is located on more than just a dorsal hand. The fact that you have 3 small dots (which may or may not be telang) indicate this is a highly unlikely possibility. Continue to follow with your rheumatologist at your regular visits. ...Read more
Ana positive c3c low and low phosphate no symptoms of anything does this mean lupus or since ANA was nucleolar scleroderma or not necessarily auto immune issue?
Low amylase blood level, tryglerides 934, cholesterol 264, HDL 42, non HDl 226, creatine 1, 09, bun 23, I have lupus/scleroderma ana positive, ifa pos.
Hyperlipidemia: Your serum lipids are very abnormal and require dietary and most likely medication for treatment. If untreated you are predisposed to cardiovascular complications. Very high triglycerides predispose to pancreatitis. Your physician and/ or rheumatologist will refer you to a dietitian and advise you on medications, avoidance of alcohol and the follow-up needed. ...Read more
BAD Gerd x4 months I have lupus but very mild scl-70&anticentromere neg no skin issues no raynauds, could I have Scleroderma, scared PPI won't work! ?
Try the PPI.: Give it 1-2 weeks. Tell ur doc. ...Read more
Can swelling of fingers, along with knuckle, wrist pain and redness on hands be a sign of which, scleroderma or lupus or both...No reynaurds here.
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