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Doctor insights on: Difference Between Humira Enbrel Side Effects

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Dr. Ronald Krauser
Board Certified, Rheumatology
46 years in practice
65M people helped
1

1
What are the side effects of tnf inhibitors such as humira and enbrel?

What are the side effects of tnf inhibitors such as humira and enbrel?

Infection risk: The major risk with these agents is infection. Other problems are very rare. ...Read more

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Dr. Peter Kurzweil
Board Certified
44 years in practice
16M people helped
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Dr. Robert Lowe
114 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


Dr. Malik Spady
Board Certified, Rheumatology
17 years in practice
16K people helped
2

2
Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade Which is better ? I'm confused snd do know what to do!

Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade   Which is better ? I'm confused snd do know what to do!

TNF Inhibitors: All of the medications offered to your child work in similar ways the difference is how the meds are given. Humira is an injection that can be done at home every two weeks, while remicaide is an IV medication that must be done in an infusion unit or hospital. These medication have similar side effects and benefits. My advice is try the medication that is least disruptive to your lifestyle. ...Read more

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Dr. Peter Kurzweil
Board Certified
44 years in practice
16M people helped
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Dr. John Chiu
Board Certified, Allergy and Immunology
51 years in practice
21M people helped
4

4
My RA doc wants me to take Enbrel/ Humira. Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

My RA doc wants me to take Enbrel/ Humira. Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

Talk to RA doctor: These are issues which need be discussed with your RA doctor. In medicine, most decisions made are based on risk/benefit ratio and without knowing that, it is impossible to provide you with an answer in this type of interaction. ...Read more

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Dr. Peter Kurzweil
Board Certified
44 years in practice
16M people helped
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Dr. Ronald Krauser
Board Certified, Rheumatology
46 years in practice
65M people helped
5

5
What is the difference in mechanism or humira and enbrel?

None: There both basically work by the same mechanism which is inhibition of tnp. ...Read more

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Dr. Thomas Namey
Board Certified, Rheumatology
42 years in practice
69M people helped
6

6
Is there a difference in humira and enbrel treatment of psoriasis?

Is there a difference in humira and enbrel treatment of psoriasis?

No great...: No great differences. Enbrel is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed! ...Read more

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Dr. Pierre Moeser
Board Certified, Rheumatology
2M people helped
7

7
Is there a waiting period between changing from enbrel to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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Dr. Stratos Christianakis
Board Certified, Rheumatology
12 years in practice
117K people helped
8

8
I was on humira and felt terrible, is enbrel any better?

I was on humira and felt terrible, is enbrel any better?

Possibly: Fortunately, there are many options for inflammatory arthritis like RA or psoriatic arthritis, and since everyone is unique, one can have a very unique response (good or bad) to unique meds. So yes, it is possible that you respond well to Enbrel just as it is possible that you feel bad on it as well. Depending on the severity of the condition, risks and benefits need to be weighed prior to start. ...Read more

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Dr. George Gataky
Board Certified, Dermatology
53 years in practice
40K people helped
9

9
Are there other alternatives to enbrel and humira?

Yes: It depends on the disease being treated. For psoriasis (my field is dermatology), there is infliximab (remicade), ustekinemab (stelara), alefacept (amevive) - not used much now and golimumab (simponi) - not used much either. ...Read more

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Dr. Tracy Lovell
Board Certified, Rheumatology
15 years in practice
6M people helped
10

10
What's average amount of time people can take biologics (ex: humira or enbrel) before developing an immunity to it? Do all patients develop immunity?

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more

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Dr. Robert Lowe
130 doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more


Dr. Robert Lowe
158 doctors shared insights

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Dr. Peter Kurzweil
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44 years in practice
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