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Doctor insights on: Difference Between Humira Enbrel Side Effects

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What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more

Dr. Robert Lowe
125 Doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


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Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!

Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!

TNF Inhibitors: All of the medications offered to your child work in similar ways the difference is how the meds are given. Humira (adalimumab) is an injection that can be done at home every two weeks, while remicaide is an IV medication that must be done in an infusion unit or hospital. These medication have similar side effects and benefits. My advice is try the medication that is least disruptive to your lifestyle. ...Read more

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My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

Talk to RA doctor: These are issues which need be discussed with your RA doctor. In medicine, most decisions made are based on risk/benefit ratio and without knowing that, it is impossible to provide you with an answer in this type of interaction. ...Read more

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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! Both should be tried only after Methotrexate therapy has failed! ...Read more

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What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more

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Are there other alternatives to enbrel (etanercept) and humira?

Many!: Methotrexate, sulfasalazine, Imuran, and other non-biologics.

Other TNF-alpha inhibitors exist, such as Simponi and Remicade! ...Read more

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I was on humira and felt terrible, is enbrel (etanercept) any better?

Switching meds: The current recommendation is to try a medication with a different mechanism of action. That being said, before there were so many options, switching between Enbrel and Humira was quite common. Sometimes it helps, just as sometimes one pill in a class of drugs works better than another. ...Read more

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Is enbrel (etanercept) or humira a narcotic drug?

Is enbrel (etanercept) or humira a narcotic drug?

No: Enbrel (etanercept) and Humira (adalimumab) are tumor necrosis factor-alpha (tnfa) blockers. They are not related to narcotic medications. ...Read more

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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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With other tnf inhibitors such as humira and enbrel (etanercept) are there?

See list: In the usa, the available tnf inhibitors are Adalimumab (humira), Etanercept (enbrel), certolizumab pegol (cimzia), golimumab (simponi), and Infliximab (remicade). ...Read more

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On actemra (tocilizumab) IV (dose increase in dec)and methotrexate for 5 mon now but still having bad flare ups. Tried humira, enbrel, etc. Since diagnosis in Dec 2013?

Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more

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Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte. Do u think psorias will clear? Y did humira (adalimumab) stop working? Stress overpower it?

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more

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Psoriasis+psor. Arthritis. Methotrexate 15mg for 2 mos. Already+humira weekly. Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe. Ok?

Nod to others:: Humira is a tnfa antibody, and is similar to envbrel. Remicade (infliximab) is an antibody to the tnfa receptor, so it works differently. But I would have tried you on leflunomide, and oral drug, before starting biologics. ...Read more

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What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?

What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?

See details: People who are stable on TNF biologics do not require blood test monitoring more than once every 3 months. Those in my practice who have been stable for years only have monitoring every 6 months. ...Read more

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Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more

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RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis: There are a number of newer medications that could help you. Xeljanz works by disrupting cytokine and growth factor signaling pathways. A trial of the medication is useful to see whether it helps you. Other medications that might help include Remicade (infliximab) and Apremilast ...Read more

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Does anyone know side effects of enbrel (etanercept)?

Etanercept: Read more here:

http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a602013.Html.

Get a more detailed answer ›
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Am starting a weekly injection of enbrel (etanercept) but very scared of side effects? Plz advise

Am starting a weekly injection of enbrel (etanercept) but very scared of side effects? Plz advise

See details: Enbrel (etanercept) is an incredibly effective therapy for several types of inflammatory arthritis. The risks are low with infection the most common one. The benefits far outweigh the risks as it prevents joint damage. Discuss your fears with your rheumatologist. ...Read more

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To start taking enbrel (etanercept) --any bad side effects?

To start taking enbrel (etanercept) --any bad side effects?

Potentially: Enbrel (etanercept) is in a class of drugs that can treat diseases such as ra. But it does have potential side effects such as serious infections. It can reacitivate TB so your doctor must do appropriate tests before you start the medication. The biologics can cause an increase in skin cancers. Also headaches, skin rashes, and local injection reactions can occur. Talk to your doctor, read about the med. ...Read more

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Am taking now enbrel (etanercept) and methotrexate till now no side effects. If I kept taking them will I have bad side effect?

Impossible to answer: The risk of long term therapy is relatively low. Infection is the major risk but studies have suggested that Enbrel (etanercept) has less risk than other meds in its class. The benefits, however, are enormous. These meds prevent joint damage and deformity. ...Read more

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What are Enbrel (etanercept) side effects?

What are Enbrel (etanercept) side effects?

See details: Infection is the greatest risk. Other side effects include reduction in blood counts, liver disease, neurologic disorders and a possible increased risk of lymphoma. ...Read more

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I am going on enbrel (etanercept) I know the side effects but want to keep my life as normal as possible. Any suggestion?

I am going on enbrel (etanercept) I know the side effects but want to keep my life as normal as possible. Any suggestion?

See details: I am not certain what you mean. The Enbrel (etanercept) is an extremely effective therapy with only modest risk. You keep your life normal by controlling your arthritis. ...Read more

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Do you take humira (adalimumab)? What side effects have you noticed?

Biologic side effec: Humira (adalimumab) is an anti-tumor necrosis factor monoclonal antibody. It can interfer with the activity of rheumatoid arthritis and crohn's and help patients. It does suppress the immune protection of the body and there are a long list of side effects: the most common is increased risk of infections and we have to monitor you for that. Most of the others on the list can occur and we follow you. ...Read more

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What are the side effects of humira (adalimumab) that people worry about?

What are the side effects of humira (adalimumab) that people worry about?

Risk of infection.: Increased risk for infection and modest increase in certain malignacies--the overwhelming patients on the drug have nothing to worry about, but the increase is definite. Also, life insurance difficulties will invariably appear. Do everything possible not to go on the drugs, if other options have not been tried. ...Read more

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If humira (adalimumab) will cause infection risks and many side effects, so if we stopped it would those infection be gone and gain a great health again?

If humira (adalimumab) will cause infection risks and many side effects, so if we stopped it would those infection be gone and gain a great health again?

Adalimumab: This tnf blocker has significant risks associated with its use, but the diseases for which it is prescribed (in your case presume rheumatoid arthritis) may not be controlled otherwise. This needs to be discussed with your doctor and a full understanding of risks and benefits developed. ...Read more

Dr. Robert Lowe
143 Doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more


Dr. Robert Lowe
177 Doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more