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Doctor insights on: Diarrhea Causes Metabolic Acidosis Or Alkalosis

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Why does respiratory alkalosis cause hypokalemia while metabolic acidosis causes hyperkalemia?

Why does respiratory alkalosis cause hypokalemia while metabolic acidosis causes hyperkalemia?

K and alkalosis acid: Blood K is sensitive to blood pH.(hydrogen ion concentration). When H gets too high (acidosis) it moves into cells to protect from death from too much acid. As H+ moves into cells a + ion must move out. This is usually K+. Thus, hyperK. When H+ gets too low (alkalosis) in blood H+ moves from cell to blood to prevent death from low H+. As H+ moves out of cell K+ moves in. Thus blood K goes down. ...Read more

Dr. Fred McCurdy
62 doctors shared insights

Metabolic Acidosis (Definition)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss ...Read more


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Normal CBC, CMP & electrolytes. Does this exclude acid/base problems such as metabolic acidosis or alkalosis??

Sort of: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, just the fact that you are asking this question is sufficient to conclude that you do not have serious acid/base disorder. ...Read more

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How does the renal system compensates for metabolic acidosis and alkalosis?

How does the renal system compensates for metabolic acidosis and alkalosis?

Slowly & effectively: In response to acidosis, the kidney increases reabsorbtion of bicarbonate (sodium bicarbonate) from the tubular fluid, secretes more hydrogen ions, and generate more bicarbonate (sodium bicarbonate). Ammoniagenesis leads to increased formation of the buffering compounds. In responses to alkalosis, the kidney excretes more bicarbonate (sodium bicarbonate), decreases hydrogen ion secretion, and lowers rates of glutamine metabolism and ammonium excretion. ...Read more

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Can you tell me how the renal system compensates for metabolic acidosis and alkalosis?

Metabolic issues: The kidneys are very smart at keeping the body at the ph level. The kidneys are capable of getting rid of large amounts of acids (hydrogen ions) and reabsorbing bicarbonate (sodium bicarbonate) to keep the body in homeostasis. We excrete acid (h+) through titratable acidity and ammonium. ...Read more

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Abg result: mixed metabolic acidosis and respiratory alkalosis with more than adequate oxygenation. What's the meaning of this? Thank you.

Abg result: mixed metabolic acidosis and respiratory alkalosis with more than adequate oxygenation.  What's the meaning of this? Thank you.

Acid-base disorder: To give a clear answer we need to have the actual values for the ph, pco2, and the tco2 (usually called bicarbonate). A mixed disorder needs to be broken into the primary disorder and then if other disorders are present, are they primary or secondary. Normal oxygenation not relevant to this problem. Could be anxiety or medication for the resp alkalosis with a secondary hyperchloremic "acidosis". ...Read more

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Is serum Osmolality typically elevated in metabolic acidosis/alkalosis and ethylene glycol poisoning?

Yes: Particularly with ethylene glycol poisoning.
For good health — Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Is it possible for diarrhea to cause the blood pH to indicate acidosis or alkalosis?

Acidosis: With severe diarrhea, metabolic acidosis is frequent and can result in severe complications depending on extent and duration of the diarrhea as well as the degree of rehydration. The acidosis results from loss of K+ and bicarbonate (sodium bicarbonate) from excess liquid stool. The blood pH is normally maintained at 7.4. Below 7.35, metabolic acidosis is present. ...Read more

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When you have diarrhea and you lose intestinal juices, does that lead to blood pH undergoing acidosis or alkalosis?

Acidosis: When one has severe diarrhea or takes too many laxatives there is a resulting change in the balanced pH of the blood referred to as hyperchloremic acidosis. The diminution of bicarbonate (sodium bicarbonate) levels lost in the liquid stool results in this problem and must be compensated by minimizing or controlling the diarrhea and taking alkaline material P. O to return the blood pH to normal. ...Read more

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When a patient has metabolic acidosis from prolong diarrhea, what has happened in the gut?

When a patient has metabolic acidosis from prolong diarrhea, what has happened in the gut?

Several possible: Diarrheic stools cause the body to lose bicarbonate, (sodium bicarbonate) and if sufficiently severe this will create metabolic acidosis. If the diarrhea is a manifestation of systemic disease this can produce a metabolic anion-gap acidosis. In either event a doctor should be seen asap. ...Read more

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Can hypercalcemia be caused because the body is trying to protect you from negative effects of mild/severe acidosis (metabolic acidosis, perhaps)?

Hypercalcemia: The answer to your question is, unfortunately, "no". Hypercalcemia (h) due to hyperparathyroidism is seen with a metabolic acidosis, it is not a defense against acidosis. H is usually not caused by bengin causes. If you, or someone you know, has h, see an endocrinolgoist as soon as possible. Goo luck. ...Read more

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What're some causes of metabolic acidosis?

Many causes: This is more of a clinical site. Try googling other sites for basic science stuff. ...Read more

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How can metabolic acidosis cause kussmaul breathing?

How can metabolic acidosis cause kussmaul breathing?

Yes.: Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis (DKA) but also renal failure. It is a form of hyperventilation, which is any breathing pattern that reduces carbon dioxide in the blood due to increased rate or depth of respiration.
In metabolic acidosis, breathing is first rapid and shallow. ...Read more

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Can topamax (topiramate) cause metabolic acidosis?

Can topamax (topiramate) cause metabolic acidosis?

Yes: Among the side effects, including cognitive issues, narrow angle glaucoma, heat stroke risk in kids, kidney stones; is also, metabolic acidosis, which can potentially be life threatening. It has been associated with kidney disease, and surgery. It is advised to stop topamax (topiramate) if surgery is planned. ...Read more

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Could use expert help with why a fever causes metabolic acidosis?

Doesn't: Fever by itself will not cause a metabolic acidosis. But when associated with sepsis can be due to lactic acidosis, with starvation ketoacidosis. Infections are frequently associated with these conditions very ill patients, this is not your every day fever. ...Read more

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Husband in the ER in severe metabolic acidosis. What does this mean, and what could be the cause?

Husband in the ER in severe metabolic acidosis. What does this mean, and what could be the cause?

Many causes: Kidney failure has to be ruled out first. Sepsis, i.e. Infection is important to rule out as well. If has diabetes need to make sure it is not diabetic ketoacidosis. Also, important to make sure it is not due to metformin (glucophage) if takes it for diabetes. Other rare causes include Aspirin poisoning and antifreeze poisoning will be ruled out by his doctors. ...Read more

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Severe infection causes metabolic acidosis or dka?

Depends: Sepsis can cause a metabolic acidosis, but if the patient also has diabetes (especially type 1), then diabetic ketoacidosis may also occur. ...Read more

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Could metabolic acidosis be one possible cause of rosacea?

Could metabolic acidosis be one possible cause of rosacea?

Not likely: Rosacea is usually caused by or aggravated by sun or wind exposure, spices, and alcohol. Metabolic acidosis is not usually a cause, but I don't know whether it would aggravate it. A dermatologist is best qualified to answer your question and treat rosacea. ...Read more

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How does high chloride cause a (non-anion gap) metabolic acidosis?

See below: Please consult this site for the information. It is more involved than the 400 characters will allow.

http://emedicine.medscape.com/article/240809-overview ...Read more

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How can diabetic ketoacidosis (w/ metabolic acidosis) causes respiratory failure?

Due to acidosis.,,: The metabolic acidosis causes a respiratory compensation in an attempt by the body to keep the blood ph normal. The respiratory compensation is to increase minute ventilation (both respiratory rate and volume per breath!). So, the person with severe metabolic acidosis will be breathing fast and deeply. Doing this for an extended period can lead to fatigue resulting in respiratory failure. ...Read more

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I take KRISTALOSE/Lactulose daily. Can this cause lactic or metabolic acidosis? Are there any recommendations for monitoring?

I take KRISTALOSE/Lactulose daily. Can this cause lactic or metabolic acidosis? Are there any recommendations for monitoring?

No, It is inert: Kristalose, a brand of lactulose, is an indigestible disaccharide for treating constipation. It arrives intact in the large bowel. Bacteria break it down to lactic and formic acid increasing osmotic pressure, drawing in water, softening stool in one to two days due to transit time to the colon. Antacids may inhibit its effect. In the elderly, it may disrupt electrolyte balance in six months. ...Read more

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Is metformin dangerous with diet-induced(not diabetes-induced)ketosis? Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Is metformin dangerous with diet-induced(not diabetes-induced)ketosis? Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Its possible: I have many patients on metformin and in ketosis and its sometimes fine but you must watch out for hypoglycemia. For example if on a regular diet you require metformin but then go into ketosis (which will severely reduce your' blood sugar) if you keep taking the same dose of metformin you could become hypoglycemic and this needs to be monitored by your' doctor. ...Read more

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Please help! What is the association between metabolic acidosis caused by high levels of lactate with thiamine deficiency?

Please help! What is the association between metabolic acidosis caused by high levels of lactate with thiamine deficiency?

Possible mitochon- : Rial disorder. Thiamine-vitamin B1-is a cofactor for energy production, which occurs primarily in mitochondria. When mitochondria become sick, anaerobic metabolism occurs, producing lactic acid. The most recognized cause of thiamine deficiency is alcohol. Thiamine is destroyed by sulfites which are used commonly by the food industry for preservatives. I suggest a clinical genetics consultation ...Read more

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What to do if I have respiratory acidosis compensating for metabolic alkalosis or is metabolic alkalosis compensating for respiratory acidosis?

What to do if I have respiratory acidosis compensating for metabolic alkalosis or is metabolic alkalosis compensating for respiratory acidosis?

Difference....: If your ph in your blood is lower than normal, then you have an acidosis. If the ph in your blood is higher than normal, then you have an alkalosis. To figure out if the abnormality is respiratory or metabolic, you need to know the carbon dioxide level. An arterial blood gas test would give the information needed to diagnose the disorder, including whether there is compensation! ...Read more

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Would a normal CMP with electrolytes & kidney functioning rule out metabolic/respitory acidosis or alkalosis. ?

Need more informatio: To perform a complete analysis blood sample should include and arterial sample for blood (abg) gases which will aid in a complete analysis and possible diagnosis ...Read more

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What symptoms characterize metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases. This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

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What are the symptoms common to metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases. This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

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What is the definition or description of: metabolic acidosis?

What is the definition or description of: metabolic acidosis?

Decreased pH: Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally, any loss of bicarb (diarrhea etc). ...Read more

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Need expert help here. What are some ways of treating metabolic acidosis?

Correct the problem: Metabolic acidosis from renal tubular disease is treated with bicarbonate, (sodium bicarbonate) lactic acidosis requires treating the source of the acid production, ketoacidosis requires relief of the diabetes or starvation with Insulin and carbohydrates. The source of the imbalance for acidosis must be identified and corrected. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more


Dr. Oscar Novick
2,187 doctors shared insights

Loose Stools (Definition)

Loose stools is a symptom in which a person's stool (poop) does not hold its shape after it goes into the toilet. Instead of remaining a shaped piece of poop, the poop spreads out in the toilet bowl water. Very loose stool is called diarrhea. Loose stool can be caused by infections, certain foods or drinks, ...Read more