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Doctor insights on: Dialysis And Plasmapheresis

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Plasma Exchange (Definition)

Plasmapheresis (plasma exchange) is a process involving the following steps: 1.Whole blood is withdrawn from the person. 2.The liquid portion or plasma is removed from the blood and replaced. 3.The blood, with all its red and white blood cells, is transfused back into the person. Usually made by an automated procedure and in precense of especialized healthcare ...Read more


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How is plasmapheresis performed?

How is plasmapheresis performed?

Using a machine: A cell separator is used. Access to a vein is needed, using either needles or a catheter. Blood is drawn from the person, and goes into a centrifuge which separates the liquid part of blood (the plasma) from the cellular parts. The plasma is collected and replaced with some other liquid as the blood is returned. It can be done either for treatment of disease, or to collect blood components. ...Read more

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How can I get ready for plasmapheresis?

How can I get ready for plasmapheresis?

Prepare yourself: Read up on the procedure itself and the circumstances surrounding your procedure. I donated platelets for another person way-back-when and it's a physical challenge but not something that a tough person need fear. Especially, think about the purpose -- gaining / regaining health for yourself or another person to do meaningful things, achieve life goals. Best wishes. ...Read more

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Where do I go to get a plasmapheresis done?

Hospital: Your doctor will arrange that for you. Usually it is arranged/performed in a hospital setting. ...Read more

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How common is it for someone to need a plasmapheresis?

How common is it for someone to need a plasmapheresis?

Not commom: Some blood disorder, neurological, or rheumatological are treated with plasmapheresis. ...Read more

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What is the definition or description of: plasmapheresis?

What is the definition or description of: plasmapheresis?

Removal of plasma: It is a procedure whereby blood is taken out of the patient the blood cells are separated from the liquid or plasma and then the blood cells are given back to the patient. This is often used to treat disorders of the immune system. Antibodies from the immune system are removed in the plasma. ...Read more

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Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

No.: Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation. ...Read more

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Is there any use of plasmapheresis in anaphylaxic drug allergy?

Is there any use of plasmapheresis in anaphylaxic drug allergy?

Probably not: Treatment of anaphylaxis from a drug allergy involves stopping the medication and appropriate use of epi, antihistamines and possible steroids. Plasmapheresis does not play a role in management of drug allergy. ...Read more

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What is the indication for plasmapheresis in anaphylaxic drug allergy?

What is the indication for plasmapheresis in anaphylaxic drug allergy?

Distinctly unusual: It would be distinctly unusual to use plasmapheresis for drug allergy reaction. The treatment for anaphylactic drug allergic reaction is to stop the medication and treat the patient with appropriate medications. ...Read more

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My father age 70 diabitic has been diagonize with CIDP. Neuro suggest IVIG or plasmapheresis. I wanted to know which one is better for him.

My father age 70 diabitic has been diagonize with CIDP. Neuro suggest IVIG or plasmapheresis. I wanted to know which one is better for him.

Better?: This is a tough call because both options are appropriate management.
If you can, please go to a local Library and have them point you to a few books that can help you understand the options for your father's care.
All should go well. Please let me know how things go. ...Read more

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When is the proper time to start plasmapharesis in ttp?

When is the proper time to start plasmapharesis in ttp?

ASAP: This is a medical emergency. Plasma exchange should commence straight away. ...Read more

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What's plasma exchange?

What's plasma exchange?

Plasma exchange: Plasma exchange is when, using a special machine much like a dialysis machine, whole blood is taken from a vein in your arm and spun in a centrifuge so that the plasma floats to the top to be removed, and the leftover blood is returned to your body. It is used to treat a condition known as ttp. Plasmapheresis is when plasma is removed, but Albumin is given back. ...Read more

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What is the definition or description of: plasma exchange?

Removing plasma: Plasmapheresis (plasma exchange) is a process involving the following steps:

1.Whole blood is withdrawn from the person.
2.The liquid portion or plasma is removed from the blood and replaced.
3.The blood, with all its red and white blood cells, is transfused back into the person.

Usually made by an automated procedure and in precense of especialized healthcare personnel that ensures safety. ...Read more

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Having transverse myeltis for 14 months is it to late to have plasma exchange or ivig?

Having transverse myeltis for 14 months is it to late to have plasma exchange or ivig?

Yes.: If your symptoms is not getting worse, no new signs of spinal cord damage, usually it is not necessary to have such kind treatment. However, the damage to your spine is on going or new symptoms occurs, such as expanding the injury level, you need receive this kind treatment to stop it. ...Read more

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I have had 4 temp cath placed for plasmaphoresis for mg crisis. Can you explain the advantage of having a fistula instead of more temp catheters?

I have had 4 temp cath placed for plasmaphoresis for mg crisis. Can you explain the advantage of having a fistula instead of more temp catheters?

A fistula: Provides a "high flow" state which allows for reliable access if needs are defined as chronic. It is usually in the arm, so the risk of line placement is not there. A fistula too can develop issues and require revisions. It takes several months to "mature" so it is not an immediate solution to the access issue. ...Read more

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What about treating pandas with plasma exchange or immunoglobulin (ivig)?

What about treating pandas with plasma exchange or immunoglobulin (ivig)?

No verdict: This is not a slam dunk decision. There may be something to it but the final word is not yet in. There is ongoing research in this area. The treatments you mention can be risky, especially for a child. Also in many cases symptoms of pandas improve spontaneously with the passage of time. For more information try this nih link: http://intramural. Nimh. Nih. Gov/pdn/web. Htm. ...Read more

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Is a plasma exchange the best treatment for neuromytonia (isaacs syndrome)?

Is a plasma exchange the best treatment for neuromytonia (isaacs syndrome)?

Not usually: The inherited forms do not typically respond to plasma exchange. If you are the only person in the family who has the disorder, you may benefit from plasma exchange. Symptoms usually come back not long after the intervention. ...Read more

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Why plasma exchange is not curative for multiple sclerosis? Thanks for answering

Good question: Plasmaphereis (plasma exchange) is used when steroids fail in controlling acute relapses of the disease. Why is it not curative: because it is an immune system dysfunction, I.e. the plasma exchange will help for a short period, the the immune system will act again necessitating another treatment, so no once and for all treatment with plasma exchange. Long term management requires immuno-modulatin ...Read more

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Risks of kidney transplant and plasma exchange?

Risks of kidney transplant and plasma exchange?

Not very harmful: If someone spoke to you about plasma exchange, then the issue is the presence of anti-donor antibodies in the recipient. The procedure removes the plasma containing the antibodies. The procedure is used either at the time (or just before) the transplant to prevent rejection in sensitized patients. Or, after the transplant if antibody mediated rejection has occurred. ...Read more

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How can plasma exchange help multiple sclerosis patients?

How can plasma exchange help multiple sclerosis patients?

Relapse Rx: Plasmapheresis is usually reserved for patients with relapsing remitting ms who are not responding to either steroids or acth, and is typically third line. Important to successfully reverse all relapses as 50% of untreated relapses will not reverse and provide added disability. Since there is risk with plasma exchange, need to work with a very experienced treatment team. ...Read more

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How does getting a plasma exchange help patients with guillain- barre syndrome?

How does getting a plasma exchange help patients with guillain- barre syndrome?

Antibodies in the: Plasma fraction are driving the nerve injury. Remove the immune proteins to arrest the process. ...Read more

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Kidney transplant needed. Confused about plasma exchange?

Kidney transplant needed. Confused about plasma exchange?

Removes antibodies: Plasma exchange or plasmapheresis is designed to remove antibodies (proteins) from the plasma fraction of the blood, which is then replaced with other plasma or albumin. It is done when the recipient has antibodies targeting the hla antigens in the donor. It may be done before or after the transplant; and is useful to prevent or treat rejections. ...Read more

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What is the preferred mode of treatment for guillain barre syndrome: immunoglobulin or plasmepheresis?

What is the preferred mode of treatment for guillain barre syndrome: immunoglobulin or plasmepheresis?

IVIG: Recent evidence supports use of ivig if disease is evolving rapidly toward total paralysis. Benefit is similar to plasmapheresis but better tolerated and easier to manage in most hospital settings. ...Read more

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My dad has kidney failure, but also has really high pth and a high IGA. Would this be enough to get a prescription for plasma exchange/which dr?

My dad has kidney failure, but also has really high pth and a high IGA. Would this be enough to get a prescription for plasma exchange/which dr?

Kidney failure: It is up to the doctor to decide what treatment is necessary when there is high PTH and high IGA.
Please have a discussion with your dad's doctor and begin to understand what might or might not be necessary.
My sense is that dad will have different treatment. Please let me know how it goes. ...Read more

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How is dialysis performed?

Dialysis: Dialysis can be done through the blood (hemodialysis) or through the abdomen (peritoneal dialysis). Hemodialysis involves passing the blood across and filter to purify it / remove toxins and remove water. Peritoneal dialysis takes advantage of the membrane within the abdomen to act as a filter. In either case toxins are removed from the blood stream. ...Read more

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How many forms of dialysis are there?

2 peritoneal & hemo: The 2 types of dialysis are hemodialysis and peritoneal. Both are effective but have pros and cons. Hemodialysis is generally done at a dialysis center three times a week and requires "access" into the blood stream, a fistula is preferred. Peritoneal dialysis is done at home through a catheter (tube) inserted into the abdominal cavity. You should discuss with your nephrologist what is best for you. ...Read more

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My creati ine is 480 do I need dialysis?

My creati ine is 480 do I need dialysis?

Not clear: I'm not sure on the units in your value or if there is a decimal missing.
A creatinine of 4.80 mg/dl is abnormal and requires investigation.
A creatinine of 480 micromol/l is also elevated and requires evaluation. ...Read more

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What is fatty deposit in dialysis tubing?

Not sure: Couild you be more explicit, I never heard about that akthough I take care of dialysis patients. ...Read more

Dr. Quresh Khairullah
520 Doctors shared insights

Dialysis (Definition)

Simple answer is that it is a medical technology used primarily to provide an artificial replacement for lost kidney function in people with renal failure. Hemodialysis remove wastes and excess water from the blood by circulating blood outside the body through an external filter, called a dialyzer. Blood and dialysate flow through in opposite directions and the ...Read more


Dr. Brad Goldenberg
15 Doctors shared insights

Plasmapheresis (Definition)

It is a procedure whereby blood is taken out of the patient the blood cells are separated from the liquid or plasma and then the blood cells are given back to the patient. This is often used to treat disorders of the immune system. Antibodies from the immune system are ...Read more