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Doctor insights on: Diagnostic Test For Sickle Cell Anemia

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Is there prenatal diagnosis or test for sickle cell anemia?

Is there prenatal diagnosis or test for sickle cell anemia?

Yes there is: Check this web site it will show all detail. http://sickle.bwh.harvard.edu/scd_prenatal.html. ...Read more

Dr. James Ball
344 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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When do you test for sickle cell anemia?

When do you test for sickle cell anemia?

Sickle cell testing: In the United States, all states mandate testing for sickle cell anemia as part of their newborn screening programs. The test uses blood from the same blood samples used for other routine newborn screening tests. The test can show whether a newborn infant has sickle hemoglobin (from http://www.Nhlbi.Nih.Gov/health/health-topics/topics/sca/diagnosis.Html). ...Read more

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Why is it more difficult to test for cystic fibrosis than it is to test for sickle-cell anemia?

Why is it more difficult to test for cystic fibrosis than it is to test for sickle-cell anemia?

More tests needed: Sickle cell disease is somewhat easier to diagnose. It is a genetic blood disorder caused by abnormal hemoglobin which tend to aggregate after unloading oxygen forming long, rod-like strictures that cause the red cells to assume a sickle shape. These sickle red cells cannot squeeze through small blood vessel and cause anoxia in organs.Cystic fibrosis is more complex to define resulting from failure to remethylate and shut off MUC5ac, an oncofetal gene which produces mucin in the fetus. Chest X ray and lung function tests may indicate problems from excess mucin. ...Read more

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I know that the typical test for sickle-cell anemia is a hemoglobin electrophoresis, but will you be able to see the sickle shape of the blood cells?

I know that the typical test for sickle-cell anemia is a hemoglobin electrophoresis, but will you be able to see the sickle shape of the blood cells?

Yes: Sick led cells are readily seen on a peripheral blood smear. It's worth knowing that the irreversibly sick led cells that you see on a smear are not necessarily the ones that cause the problem. In order for a cell at risk for sickling to occlude the small blood vessels (capillaries), they first must be able to enter them. In other words they must be deformable. They become occlusive in the vessel. ...Read more

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At what age can I test to see if I am a carrier for sickle cell anemia?

At what age can I test to see if I am a carrier for sickle cell anemia?

Late teens: Carrier testing should only be done in persons who can give intelligent informed consent. Young children should not be tested. Older teens who can give meaningful consent may be tested. ...Read more

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Can sickle-cell anemia be detected from a test?

Can sickle-cell anemia be detected from a test?

Yes: Certain blood work - i.e. Cbc, and a hemoglobin electrophoresis, - would need to be done to establish a diagnosis of sickle cell anemia. ...Read more

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How do you test fetus for sickle cell anemia?

How do you test fetus for sickle cell anemia?

Genetic test Sickle: Yes the test is done on high risk women at the 17 week of gestation by doing amniocentesis with the permission of both patents. ...Read more

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Blood test positive for sickle cell anemia doctor said she is not sure if it is the trait or the actual illness! what do I do next?

Depends: If your doctor did a sickledex that was positive, this might not distinguish between sickle trait and sickle cell disease. The next test is a hemoglobin electrophoresis. If this shows mainly HGB a with HGB s, this is sickle trait. If both a and s but more s, this is sickle/beta+ thalassemia. If only s, sickle cell disease or sickle/beta 0thalassemia. Your doctor can explain what these mean. ...Read more

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Are there other tests to determine sickle cell anemia risk if my husband is away serving in the military?

Yes: The first step is testing you for sickle cell carrier status. If not a carrier then no further testing needs to be done. If you are a carrier then the next step is check the father of the baby. If he is unavailable you could have his parents tested. If neither are a carrier then the father can not be a carrier either. If they are carriers then the fathers chances are 50% he is also. ...Read more

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What are the tests for sickle cell anemia?

Hb electrophoresis: CBC and hemoglobin electrophoresis have to be done -at least- to make a diagnosis of sickle cell anemia. ...Read more

Dr. Steven Ginsberg
940 doctors shared insights

Low Blood Count (Definition)

Low blood count is also known as Anemia. Anemia is a condition in which the body has a decreased amount of healthy red blood cells, which normally provide oxygen to body tissues. Common causes may include certain medications, chronic diseases such as cancer, a poor ...Read more


Dr. Ed Friedlander
1,258 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more