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Doctor insights on: Diagnosis Of Acute Myeloid Leukemia

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

Dr. Bernard Seif
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Anll (Definition)

Also known as AML, acute myeloid leukemia is a cancer of the white blood cells (called myeloid) cells formed in bone marrow. It often occurs in late adult or elderly patients and has usually a short development phase (hence acute). Symptoms of AML include easy bleeding or bruising or tiny red flecks on the skin ("petechiae") from low platelets; pale skin, fatigue or shortness of breath from anemia (low red blood cells); or infections (from low numbers of ...Read more


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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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Dr. Liawaty Ho Dr. Ho
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What percent of leukemias does acute myeloid leukemia represent?

Dr. Liawaty Ho Dr. Ho
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AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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What's acute myeloid leukemia?

What's acute myeloid leukemia?

See links: For a nice overview of aml, see the following pages at the national cancer institute. For adult: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient for pediatric: http://www.Cancer.Gov/cancertopics/pdq/treatment/childaml/patient. ...Read more

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What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

Types of cells: White blood cells are different with different mechanisms to pretect body from infections. Acute myeloid leukemia arise from a type of white cells called myeloid series or neutophils, cut lymphoblastic leukemiaa arise from lymph type of white cells. These two types of leukemia have different treatments and the outcome or expectations are very different, none is better than the other in general. ...Read more

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Symptomatology level of what would be the difference between acute myeloid leukemia and acute lymphoid leukemia?

Symptomatology level of what would be the difference between acute myeloid leukemia and acute lymphoid leukemia?

AML vs. ALL: The symptoms of AML and all can be quite similar since both cause anemia (low red cells) and low platelets (which causes bruising and bleeding). In addition, they both cause an increased risk of various infections. AML is more likely to cause swollen gums and lumps on the skin. All is more likely to cause neurological symptoms since it can sometimes get into the brain or spinal fluid. ...Read more

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Dr. Weili Sun Dr. Sun
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What are the symptoms of acute myeloid leukemia?

Dr. Weili Sun Dr. Sun
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Fatigue, fever etc: Acute myeloid leukemia starts from bone marrow, where normal blood cells were made. Leukemia cells will decrease the abilities of bone marrow to make normal blood cells such red blood cells (delivery oxygen); white blood cells (fight for infection), and platelets (stop bleeding). Therefore, the symptoms can be fatigue, fever, bruising or bleeding, bone pain, swollen glands, and weight loss. ...Read more

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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What is acute myeloid leukemia (aml)?

What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

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Chances of curing acute lymphoblastic leukemia in adults?

Chances of curing acute lymphoblastic leukemia in adults?

See below: About 80-90% of patients will achieve remission, but some of these patients will relapse and not be cured. Overall cure is achieved in about 40%. Those numbers come from this link: http://www.Cancer.Org/cancer/leukemia-acutelymphocyticallinadults/overviewguide/leukemia-all-overview-survival-rates. ...Read more

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Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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What is the treatment for acute myeloid leukemia?

What is the treatment for  acute myeloid leukemia?

Differs: The answers depend on patient age, overall health, and type of aml. Usually younger, healthier patients are offered aggressive chemotherapy and possible stem cell transplant, while older patients are offered less aggressive chemotherapy or supportive care alone. Here is a link to info on AML treatment: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient/page1. ...Read more

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What is acute myeloid leukemia is?

Marrow malignancy: AML is a bone marrow malignancy characterized by uncontrolled growth of leukemic cells in the bone marrow. It leads to very high white blood cell counts, anemia and thrombocytopenia (low platelets). It is rapidly fatal without prompt diagnosis and treatment. It can be cured in up to about 40% of people. ...Read more

Dr. Agos Luca Dr. Luca
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What is acute lymphoblastic leukemia (all)?

Dr. Agos Luca Dr. Luca
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Blood cancer: All is a form of leukemia which in turn is a form of cancer, more specifically blood and bone marrow cancer. The word "acute" means it progresses faster, as opposed to chronic cases that usually have a slower progression. The word "lymphoblastic" means immature lymphoid and describes the type of malignant cell involved in this leukemia, as opposed to other types of cells, for example myeloid. ...Read more

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What are the chances of curing childhood acute lymphoblastic leukemia?

Good. : This disease is curable in 80% of cases. There are many findings of the leukemia that can effect the prognosis. Some findings make the curability higher, some make it lower. Overall, there are good treatments for this disease. ...Read more

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If a person has AML - acut emyeloid leukemia, what percent of blast would suggest acute myeloblastic leukemia?

Blasts in blood/marr: Blasts are made in the bone marrow. Normally they are under 5% of all the white cells. So a Blast count in the bone marrow over 6% raises the question of Acute leukemia. Anything >30% blast count confirms a diagnosis of acute leukemia. As the blast cell numbers increase in the marrow, Blasts start to appear in the peripheral blood. That is how Leukemia is first diagnosed. ...Read more

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What are the diagnostic tests for acute lymphoblastic leukemia?

Bone marrow biopsy : The diagnosis is typically with a bone marrow biopsy, cytogenetics (dna of leukemia cells), and flow cytometry (cell surface markers of leukemia cells). ...Read more

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Dr. Liawaty Ho
1,158 doctors shared insights

Leukemia (Definition)

A cancer of blood-forming tissues, hindering the body's ...Read more