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Doctor insights on: Diabetic Nephropathy In Children

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How is diabetic nephropathy diagnosed?

How is diabetic nephropathy diagnosed?

Protein in urine: If you have diabetes, early diabetic nephropathy can be suspected if your doctor tests the urine for microalbumin, and then later for protein.Usually no need to do a kidney biopsy especially if the retina of the eye also has diabetic changes. Your nephrologists determines this. ...Read more

Dr. Jack Rubin
69 Doctors shared insights

Diabetic Nephropathy (Definition)

A progressive damaging effects to capillaries in/near glomeruli leading to local inflammatory change and scarring with subsequent malfunction in filtering the blood for reabsorbing useful blood components and excreting the unwanted metabolic wastes, which exact causes are still unclear, though, long-term high blood sugar is the culprit. This is usually a slow ...Read more


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In a nutshell, what is diabetic nephropathy?

In a nutshell, what is diabetic nephropathy?

See below: Diabetic nephropathy as the name suggests is a "disease" of the kidney in diabetics with appearance of protein in the urine and slow deterioration of kidney function. Not all patients with diabetes get nephropathy. Seek advice from a nephrologist
a kidney biopsy is not always necessary but the microscopic appearance is very typical. ...Read more

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What are the tests for diabetic nephropathy?

What are the tests for diabetic nephropathy?

Urine tests: Urinalysis, urine Albumin to creatinine ratio, blood biochemistry, serum creatinine with GFR estimation, kidney ultrasound. Tests to consider- 24 hour urine collection, ct abdomen, magnetic resonance angiography, doppler ultrasound and kidney biopsy. ...Read more

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Can you tell me what is diabetic nephropathy?

Can you tell me what is diabetic nephropathy?

Hurt kidneys: High sugars as well as high blood pressure can damage your kidneys over time. Our kidneys filter and process things. When they're hurt, they don't filter as well, and can leak protein into your urine. We check how well your kidneys are working by [1] blood test [2] urine test for microalbumin. Not everyone with diabetes gets kidney problems. Good luck. ...Read more

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What are the symptoms of diabetic nephropathy?

Edema: Diabetic nephropathy causes glomerular damage and leakage of proteins in the urine. If left untreated it may progress to generalized edema, and renal failure with symptoms of weakness, anemia, high blood pressure and heart disease. ...Read more

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What symptoms usually go along with diabetic nephropathy?

What symptoms usually go along with diabetic nephropathy?

Usually none: This term generally refers to excessive amount of protein leaking out into the urine. It is detected by urine tests, in combination with blood testing. In severe cases, in part, you may have edema (swelling). ...Read more

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What is the definition or description of: Diabetic nephropathy?

It is...: A progressive damaging effects to capillaries in/near glomeruli leading to local inflammatory change and scarring with subsequent malfunction in filtering the blood for reabsorbing useful blood components and excreting the unwanted metabolic wastes, which exact causes are still unclear, though, long-term high blood sugar is the culprit. This is usually a slow process of >5-15 years. ...Read more

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What is a good diet for someone who suffers from diabetic nephropathy?

What is a good diet for someone who suffers from diabetic nephropathy?

See below: Blood sugar control is extremely important
it is important to maintain a Albumin level in the normal range and I generally do not recommend severe protein restriction for that reason. Have a moderate restriction only if Albumin levels are normal
maintain LDL cholesterol less than 70
if you have leg swelling or high blood pressure you will need to restrict salt and fluid intake as well. ...Read more

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What is a good diet to follow for someone who suffers from diabetic nephropathy?

What is a good diet to follow for someone who suffers from diabetic nephropathy?

Control diabetes: This takes first priority. So the diet is a strict diabetes diet. Also, if not in an early stage in the nephropathy, protein restriction would be helpful. ...Read more

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Can a hit to the kidney area cause diabetic nephropathy to accelerate?

Can a hit to the kidney area cause diabetic nephropathy to accelerate?

Not blunt trauma: A physical hit to the kidney, such as during contact sports should not worsen kidney disease due to diabetes. Diabetic nephropathy is accelerated most frequently by poor diabetes control and uncontrolled hypertension. ...Read more

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Do CKD + dm = diabetic nephropathy?

Do CKD + dm = diabetic nephropathy?

CKD + DM: The answer to your question is "Yes". Diabetes is the leading cause of renal failure in the US. There are 6 stages of chronic kidney disease, with stage being that of patients on dialysis. So a diabetic, depending on the duration of diabetes, the control of blood pressure and glucose, can be in any one of stages 1-5. ...Read more

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What is the best indicator of having diabetic nephropathy?

Protein in the urine: Diabetic nephropathy is kidney disease caused by long-standing diabetes. The best indicator that diabetic nephropathy is developing is the amount of urine protein. Normally there is none, or tiny amounts of protein found. In diabetic nephropathy there will be more and more protein spilled into the urine. That's why doctors monitor urine protein, along with blood tests for kidney function. ...Read more

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How do CKD and dm relate to diabetic nephropathy?

Diabetic nephropathy: Diabetes (d) affects the kidney and can cause them to fail. The kidney disease caused by d is called "diabetic nephropathy" (dn). Before going into renal failure, those with diabetic nephropathy can go into various stages of ckd. Treatment of blood pressure elevations, proteinuria and blood glucose levels can lead to slowing of kidney failure due to dn. ...Read more

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Why is glucose excreted through your urine in diabetic nephropathy?

Why is glucose excreted through your urine in diabetic nephropathy?

Sugar in the urine: When your blood sugar is too high, your kidneys, which filter your blood, are not able to hold onto all the glucose and it spills over into the urine. ...Read more

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Which drug is most effective and safe for treating proteinuria in someone with diabetic nephropathy?

Many options: There are many drugs that can be safe and typically lay in two classes of blood pressure medicine which are called: angiotensin receptor blockers, ace-inhibitors and possibly renin inhibitors (newer class). ...Read more

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Can diabetic nephropathy cause a miscarriage?

Can diabetic nephropathy cause a miscarriage?

Miscarriage: I have not heard not read studies regarding this. I would discuss with your primary or obgyn. ...Read more

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Can enzyme supplementation aid in managing diabetic nephropathy?

Not that I know of: No management showed promise in managing diabetic nephropathy besides control of diabetes, hypertension, cholest &meds i.e. Ace/arb. Avoiding concurrent insult to the kidneys is paramount. In laboratory rates a ketogenic diet actually showed great promise however it is not tolerated or recommended in human diabetics. It further stresses the benefit of strict carbohydrate and diabetes control, though. ...Read more

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Do adenosine receptors offer new therapeutic options for diabetic nephropathy?

Do adenosine receptors offer new therapeutic options for diabetic nephropathy?

Yes: Yes recent advances in understanding the relationship between Adenosine metabolism sakowicz-burkiewicz m, pawelczyk t (2011) j physiol pharmacol. 62 (5), 505-12. ...Read more

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When should the daily dose of atenolol be reduced in patients with diabetic nephropathy?

When should the daily dose of atenolol be reduced in patients with diabetic nephropathy?

As advised: There is no set rule for decreasing the dose of atenolol. It is for blood pressure so if blood pressure is too low then it would be reduced. This does not have anything to do with diabetic neuropathy. You should only decrease atenolol as advised by your doctor. ...Read more

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What's the difference between 'diabetic nephropathy' & 'diabetic neuropathy'?

Kidney vs nerves: "nephropathy" is damage to the kidneys, and "neuropathy" is damage to nerve cells. In addition to kidneys and sensory nerves, uncontrolled diabetes can also damage blood vessels & circulation, heart, brain, eye, stomach emptying, skin, immune system and just about any organ in the body. Best way to prevent is to control blood sugar. Once there is damage, may need specialist or more advanced care. ...Read more

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How to reduce serum creatinine level in a 70 yrs old diabetic lady having diabetic nephropathy?

Unlikely: If it is truly diabetic nephropathy it cannot be reversed. Sometimes there is increase in acute conditions in which case it may decrease. You can slow down the rate of rise by controlloing bp, blood sugar. Avoid anti inflammatory pain medications. ...Read more

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Is diabetic nephropathy curable? Was diagnosed when my egfr was 34, creatinine over 2.0 and bun 24. For the past year and this week egfr is 68, creati

Diabetic kidney: From your data, it appears that you clearly had some improvement in your egfr. The "e" stands for "estimated". You may had this recovery of renal function due to a reduction of the amount of protein (p) in your urine, or relief of some obstruction. Ask your doctor to send you to a nephrologist (n) to find out what your actual GFR is with a 24 hour urine for creatinine clearance and p collection. ...Read more

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Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

NO: There are no drugs that treat diabetic nephropathy per se. Diabetic nephropathy is not a curable condition. Slowing it down can be achieved by several maneuvers including controlling diabetes and hypertension well and using drug group called ace inhibitors or arb under a close supervision of a doctor since these drugs may have significant side effects. ...Read more

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Is diabetic nephropathy curable? My original egfr 34, creatinie 2.0, bun 24. For last year including today egfr 68, creatine 1.09, bun 14.

If it is a mild: Or moderate case it can be. Severe cases are more difficult to treat. Look into metanx, a medical food containing vitamin b6, 12 and l- methylfolate. Studies reveal positive results for reversing diabetic neuropathy. ...Read more

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Can people with diabetic nephropathy take vitamin b supplements?

Diabetic Nephropathy: High-dose b vitamin therapy is not helpful in diabetic nephropathy. An article was published in the jama in 2010. High doses of b vitamins were associated with a greater chance of kidney dysfunction. ...Read more

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Is it safe to take metformin with microalbuminuria and diabetic nephropathy if these conditions are improving with lisinopril?

Is it safe to take metformin with microalbuminuria and diabetic nephropathy if these conditions are improving with lisinopril?

Metformin ; kidneys: Metformin should not be used if there is early kidney failure, which is usually defined as a creatinine of 1.4 or more. Microalbuminuria is an early sign of nephropathy, and your creatinine may be normal, and metformin may still be ok. Lisinopril will slow the progression of nephropathy, but you also need to control glucose and blood pressure. ...Read more

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Dmii, proteinuria reduced with lisinopril but still present after 4mos. Is this diabetic nephropathy & can pcp handle or do I need specialist?

Dmii, proteinuria reduced with lisinopril but still present after 4mos. Is this diabetic nephropathy & can pcp handle or do I need specialist?

Most likely: Common things are common. Fits diabetic nephropathy. I am a nephrologist so I am biased toward having you see someone like me. We can ensure that any other possible causes of kidney damage have been considered and we can assist your primary care doctor in caring for you using the latest recommendations for the evaluation and treatment of kidney disease. ...Read more

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Glimepride or metformin sustained release? Which anti diabetic tablet is safer for stage 2 renal disease (diabetic nephropathy)

Glimepride or metformin sustained release? Which anti diabetic tablet is safer for stage 2 renal disease (diabetic nephropathy)

Caution: Metformin is contraindicated as renal function declines. Glimepiride is ok, but all such agents are more potent as renal function falls since Insulin is metabolized by the kidney and Insulin levels may persist at a higher level with renal disease. Night time hypoglycemia is more common w/renal disease so monitor carefully. ...Read more

Dr. Milroy Samuel
104 Doctors shared insights

Nephropathy (Definition)

Nephropathy is a medical term that refers to disease of the kidney. There are many causes. It can be caused by high blood pressure, diabetes, uric acid, abnormal proteins, cancers, blood vessel blockages in the kidney, it can be minimal or or it can be severe ...Read more


Dr. Veeraish Chauhan
93 Doctors shared insights