Doctor insights on:
Diabetes Type 1 Pancreas Transplantation
Is transplantation of langerhans cells to a 7 years old kid with diabetes type 1 possible? Doas it have to be from a dead doner?
Diabetes is a disease of increased blood glucose levels. Glucose is a type of sugar that comes from the intake of food. Insulin is a type of hormone that removes the glucose from the blood and moves it into the cells to provide them with energy. There are two different types of diabetes: type 1 and type 2. Type 1 diabetes is when the body does not make any insulin. Therefore, glucose stays inside the blood and does not move into the cells. Type 2 diabetes, which is commonly associated with obesity, is when the body is either resistant to the effects of insulin or when the body does not produce enough insulin. Increased levels of glucose in the body causes severe damage to the ...Read more
I was new in diabetea disease.. Is there some one explain to me what is diabetes type 1 and type 2? Thank you...
Type 1 vs type 2: To use an analogy, Insulin is like a taxicab that takes sugar from the blood and delivers it into cells where it can be used or stored.Without insulin, the sugar can do nothing but build up in the blood, making it thick and spilling into the urine. In type 1, you no longer make insulin, so you must give it all by shot.In type 2 you make some, but not enough for your size.Extra is often given. ...Read moreSee 1 more doctor answer
Mostly unknown: The exact cause of type 1 diabetes is unknown. In most people with type 1 diabetes, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin-producing (islet) cells in the pancreas. Genetics may play a role in this process, and exposure to certain viruses may trigger the disease. ...Read more
MUST: Get very good glycemic control- that way with 'right' Insulin dose, your storing the food you eat (rather than it going out in urine, breaking down fat/ muscle for energy-losing weight; and if you increase calories, but not sweets, increase appropriate Insulin proportionately see dm / nutritionist specialist to help you. ...Read more
See below: Type 2 diabetes, it's increased by age, family history and (70-90%) obesity -- which causes Insulin resistance, necessitating higher Insulin by your pancreas and eventually exhausts pancreas' ability to make sufficient insulin. Symptoms are thirst, urination, weight loss, visual blurring, fatigue, etc. Type 1 is caused by lack of Insulin secretion, not excess. ...Read more
They don't.: The exact cause of type 1 diabetes is unknown. In most people with type 1 diabetes, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin-producing (islet) cells in the pancreas. Genetics may play a role in this process, and exposure to certain viruses may trigger the disease. ...Read more
No: Your weight will always be a function of how many calories you take in versus how many you burn up. If your blood sugars have been high, you would lose calories through urinating sugar. When your sugars are under control, you do not have excess sugar in the urine and therefore do not lose those calories. That is why some people notice weight gain when they start treatment for diabetes. ...Read more
Higher chances: If an immediate relative (parent, sibling, child) has type 1 diabetes (t1d), one's risk of developing t1d is 10 to 20 times the risk of the general population. The risk for a child of a parent with t1d is lower if it is the mother, rather than the father, who has diabetes. If one of the parents developed t1d before age 11, their child's risk of developing t1d is somewhat higher than these figures. ...Read moreSee 2 more doctor answers
In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more
Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only ...Read more
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