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Diabetes Insipidus Water Deprivation Test
Vasopressin test.: This is a dehydration test for diabetes insipidus. First, fluid is withheld until urine osmolality is stable. Then 5 u of vasopressin is given by subcutaneous injection. The urine and plasma osmolality/concentration is measures before and one hour after the injection. Argenine vasopressin or avp given to these patients causes a >9% rise in urine osmolality. In normal patients, it is <9%. ...Read more
Diabetes is a disease of increased blood glucose levels. Glucose is a type of sugar that comes from the intake of food. Insulin is a type of hormone that removes the glucose from the blood and moves it into the cells to provide them with energy. There are two different types of diabetes: type 1 and type 2. Type 1 diabetes is when the body does not make any insulin. Therefore, glucose stays inside the blood and does not move into the cells. Type 2 diabetes, which is commonly associated with obesity, is when the body is either resistant to the effects of insulin or when the body does not produce enough insulin. Increased levels of glucose in the body causes severe damage to the ...Read more
During fluid deprivation test, the ADH (vasopressin) level dropped down to 1/3 of pre test level and below reference values. Is that a sign of diabetes insipidus?
Not necessarily: The most important thing to be following in a water deprivation test is the urine and serum osmolality. If the serum osmolality rises above normal, but the urine osmolality does not rise significantly, you have diabetes insipidus. Measuring ADH (vasopressin) levels can be unreliable. ...Read more
Dx'd w/partial idiopathic central diabetes insipidus 20yrs ago by H20deprivation test. Put on DDAVP (desmopressin). No longer needed DDAVP (desmopressin) after 2 yrs.Sx better.Why?
Central DI: Hard to answer. It was called "idiopathic", meaning no clear cause. In a 13 yr old, the causes could include a tumor, certain medications, trauma/surgery, meningitis, etc. It is possible that something happened back then but then resolved. Is it possible that you now still have partial DI? Under usual conditions, don't need DDAVP, (desmopressin) but under water stress you may. See your Endocrinologist. ...Read more
If the cause disappe: The degree of recovery is largely dependent on the underlying cause of the disease. Complete resolution of symptoms may not be seen in individuals with severe disease. Chronic diabetes insipidus, although inconvenient, is not usually a dire medical condition. When properly treated, diabetes insipidus itself does not reduce life expectancy. The prognosis, therefore, depends on the underlying diseas. ...Read more
It depeds on reason: One component of effective management of nephrogenic diabetes insipidus is the low sodium diet. Restricted sodium intake limits renal solute load and permits full effectiveness of chorothiazide. The usual sodium intake for persons in the us is about 5000 mg/day. From a medical perspective, the low sodium restriction for treatment of hypertension is 2400 mg/day. ...Read more
What is the definition or description of: Diabetes insipidus? ANS: your pituitary doe not make ADH and you drink and pee constantly. Many with DI carry water with them at all times to avoid quick dehydration. Recommend you go to uptodate for the many questions you are asking ...Read more
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