Doctor insights on:
Diabetes Insipidus Lab Values
During fluid deprivation test, the ADH (vasopressin) level dropped down to 1/3 of pre test level and below reference values. Is that a sign of diabetes insipidus?
Not necessarily: The most important thing to be following in a water deprivation test is the urine and serum osmolality. If the serum osmolality rises above normal, but the urine osmolality does not rise significantly, you have diabetes insipidus. Measuring ADH (vasopressin) levels can be unreliable. ...Read more
Need medication: It is important to determine the cause of diabetes insipidus. It involves the absense of a pituitary hormone. Common causes are head trauma, pituitary tumors, surgery. Kidney diabetes insipidus (nephrogenic) can be caused by certain drugs, such as lithium. If your doctor knows the cause, then treating the cause can sometimes reverse it. But usually treatment with DDAVP (desmopressin) is essential. ...Read more
Thirst,lots of urine: Diabetes insipidus is a disorder that impairs the body's ability to make concentrated urine. Common symptoms in childhood might include constant thirst and large amounts of urine. There is also often a family history of the disease that can prompt an evaluation by the child's pediatrician. ...Read more
Diabetes insipidus.: What is the definition or description of: Diabetes insipidus? ANS: your pituitary doe not make ADH and you drink and pee constantly. Many with DI carry water with them at all times to avoid quick dehydration. Recommend you go to uptodate for the many questions you are asking for much more detail. ...Read more
Diabetes insipidus: 400 characters are too few to answer your question. In general, the doctor will look at a 24-hour urine collection for determination of urine volume, serum electrolyte concentrations and glucose level, urinary specific gravity, simultaneous plasma and urinary osmolality, and plasma ADH (vasopressin) level. It may also include a water deprivation test, MRI, etc. ...Read more
It depends.: Sometimes, diabetes insipidus (inability for the body to hold onto water due to the lack of or inaction of anti-diuretic hormone (adh)) is temporary after brain surgery. If permanent, usually due to a pituitary or kidney problem, it is not usually curable but can be easily treated especially if dealing with an ADH (vasopressin) deficiency. ...Read more
Rare disorder: Diabetes insipidus (di) is a rare disorder in which the kidneys cannot concentrate urine, thereby causing excessive loss of water from the body and dehydration. It can result from a problem of the pituitary gland, or from a defect in the kidneys. However, most people who think they have di are actually excessive fluid drinkers, and urinate a lot because they drink a lot. ...Read more
Vasopressin test.: This is a dehydration test for diabetes insipidus. First, fluid is withheld until urine osmolality is stable. Then 5 u of vasopressin is given by subcutaneous injection. The urine and plasma osmolality/concentration is measures before and one hour after the injection. Argenine vasopressin or avp given to these patients causes a >9% rise in urine osmolality. In normal patients, it is <9%. ...Read more
Very different: Diabetes mellitus is the typical "diabetes" that we are familiar with. It's caused by an Insulin problem (too little or just not working well (resistance)) causing elevation in blood sugar. Diabetes insipidus is a water problem characterized by lots of urination and high sodium level. It's caused by an ADH (vasopressin) (antidiuretic hormone) problem (too little or just not working well). ...Read more
Depends: There are two types of diabetes insipidus (di). In central di the patient is not making enough of a hormone to reabsorb water in the kidneys, and in nephrogenic di the kidneys don't respond to the hormone. Central di is treated with desmopressin. Nephrogenic di is treated with thiazide diuretics. Both treatments will prevent excessive thirst and decrease the amount of urine. Need to find the cause. ...Read more
Fluctuating glucose: Check your glucose levels in the evening, note if it is unusually high. High serum glucose does result in increased urination, as the body tries to clear toxic levels of glucose. Write your findings down, and share them with your Dr. A change in your management might be in order. Best Wishes! ...Read more
Diabetes insipitus is decreased production or effect of vasopressin- nephrogenic is where it's effect reduced because of a kidney issue
diabetes mellitus is a high sugar problem due to immune destruction of cells making Insulin in pancreas
They are different disease states. ...Read more
Less ADH (vasopressin) : In central diabetes insipidus(di) there is lack of antidiuretic hormone secretion from hypothalamus, or the level is low. It might even be lower at night. With your doctor agreement you may limit the liquid consumption at night and have a higher dose of your medication (desmopressin). ...Read more
I have diabetes insipidus. Is it unusual to drink between 20 up to 35 l per on a hot day. Any long term effects?
Yes, large amount: 20-35 liters is a large amount; the quantity retained is the important issue. If heart, liver, kidneys &brain control are intact &in comfortable environment, humans can often survive indefinitely on as little as 0.5 liters/day up to 25 liters/day. The 35 liters you quote is above this, but given diabetes insipidis (?ed pituitary output of antidiuretic hormone) kidneys will lose water?? Rapidly. ...Read more
Can I ever stop taking my diabetes insipidus medication
I got it after my car crash and I wanna stop taking it?
Talk to your doctor: Noone can fully answer this question except the doctor who put you on the medication in the first place. The answer depends on how severe or persistent your illness is. If you continues to urinate and have to drink water often, then you are not ready to go off it. Talk to your doctor about your individual condition. ...Read more
Follow doc's advise: You need to find out the cause so you can be treated appropriately. Often time, diabetes insipidus is just a symptom, not the cause. The hormone involved is ADH (vasopressin) (antidiuretic hormone). If the cause is in the brain, treatment is to give back ADH (vasopressin) (ddavp) either in nasal spray or pill. If the problem is at the kidney, treatment is antiinflammatory (indomethacin) and diuretics (hctz and amiloride). ...Read more
Symptoms of D Insipi:
Symptoms of diabetes insipidus are
excessive urination and extreme thorst especialy of cold water sometimes ice and ice water. Extreme urination continues throghout the day and the night adults remain healthy as long as enough water is consumed to offset the urinary loss.
In children, it interfere with eating and weight gain and growth. They present with fever, vomiting and diarrhea. ...Read more
Peeing all the time!: Diabetes insipidus (or di) is caused by either a lack of or a resistance to the hormone in your body (antidiuretic hormone) which normally allows your body to concentrate urine (so that you make less of it). Without this hormone, you produce large volumes or urine, and often patients present with excess thirst because they are on the verge of getting dehydrated from all the urine output. ...Read more
If the cause disappe: The degree of recovery is largely dependent on the underlying cause of the disease. Complete resolution of symptoms may not be seen in individuals with severe disease. Chronic diabetes insipidus, although inconvenient, is not usually a dire medical condition. When properly treated, diabetes insipidus itself does not reduce life expectancy. The prognosis, therefore, depends on the underlying diseas. ...Read more