Doctor insights on:
Developing Colon Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read moreSee 2 more doctor answers
For the most part.: Early detection via colonosocpy, not ignoring symptoms such as bleeding, change in bowels, anemia, unintentional weight loss, and not assuming all rectal bleeding is from hemorrhoids are some ways to reduce your chances and maybe prevent colon cancer from developing. ...Read moreSee 1 more doctor answer
Can be: The fastest-growers are the ones that follow genetic pathways associated with the lynch loci. They may not even be preceded by a polyp -- colonoscopy can be clean one year, and a year later, there's a cancer. That's actually quite fast as cancers go. Hope this helps. ...Read moreSee 1 more doctor answer
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer
Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more
Not always: Colon cancer tends to not have any signs or symptoms when it is early (when it is easiest to treat). That is why screening colonoscopies are so important, to remove any polyps that may become cancer, and to directly look for cancers. Colon cancer can cause bleeding from the rectum, tiredness from anemia, stool changes, or abdominal pain. Other things can cause this too. Best to be seen if ?S. ...Read moreSee 1 more doctor answer
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Yes: Yes. Many people are cured with colon cancer. If found early surgery alone may be curable. If more advanced (eg, lymph node involvement or metastatic = spread to areas outside of colon), then chemotherapy may be needed. While less likely, even a few % of people with metastatic colon ca may be cured. ...Read moreSee 2 more doctor answers
Somehow yes: There is some genetic predisposition in families with hx. Of colorectal cancer. Diet also plays a rol ( low fiber diet increases cancer). Familiar poliposis increases chances of colon cancer. Colon polyps may degenerate in cancer. Small intestine cancers are rare and difficult to find. In general there are families affected by cancers and families affected by atherosclerosis but both together too. ...Read moreSee 1 more doctor answer
Good question: That is certainly the idea behind it. It is hard to say if we are truly successful. Having a pap smear and picking up a lesion before it becomes cancer reduces your likelihood. So does removing a colon polyp before it can become a colon cancer. The problem is that having these things means you are at higher risk in the first place and you need continued watching. ...Read moreSee 1 more doctor answer
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