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Bad disease: Scleroderma is a progressive disease that affects the skin and connective tissue (including cartilage, bone, fat, and the tissue that supports the nerves and blood vessels throughout the body). There are two major forms of the disorder. One localize and could effect the whole body. ...Read more
Thickened skin: It is a thickening of the skin usually on the upper back and back of the neck. More common in diabetics and heavier people. Treatment is difficult as medicine is partially effective in preventing progression of problem. ...Read more
Clarify: There is no specific disease called "dermatosclerosis." do you mean scleroderma? If so, treatment options include drugs such as penicillamine, immunosuppressives, and antiinflammatory agents, but there is no definitive cure. If you mean something else, please let us know. ...Read moreSee 1 more doctor answer
Impossible to say: This question needs to be addressed to your own doctors. You provide no specifics but there is no possible way that any doctor who does not participate in your care could even began to answer that question ...Read more
What is best treatment to slow down scleroderma on the face? What medication, any topical creams? Exercises?
Talk to a: Rheumatologist for best information.Get a more detailed answer ›
Is gerd, which does not respond well to medications , and other intestinal problems usually indicative of scleroderma?
No, too big a leap!: "refractory" gerd may reflect: 1) too little acid suppression (insufficient acid blocker or tolerance to previously effective dose), 2) over-production of acid, 3) significant diet & behavior non-compliance, 4) incompetent lower esophageal sphincter &/or other esophageal dysmotilities, 5) delayed stomach emptying, 6) biliary/pancreatic disease, 7) non-acid reflux. Scleroderma is way down the list. ...Read moreSee 1 more doctor answer
I try to avoid toxic drugs and treatments. What can I try before I go for traditional medical care for circumscribed scleroderma?
NOT AS SEVERE: Scleroderma is a fascinating disease and has 3 main types, diffuse, limited and localized also known as morphea. Diffuse scleroderma is the most severe. Circumscribed scleroderma or morphea tends to mean a localized area of thickened skin. This tends to be less severe with few compications of other organs which is typical of diffuse scleroderma. Treament is limited. ...Read moreSee 1 more doctor answer
Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more
Hard skin: Scleroderma literally means "hard skin." it is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown. ...Read moreSee 2 more doctor answers
I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read moreSee 1 more doctor answer
Depends on type: The treatment ranges from "no treatment necessary" for mild forms of localized scleroderma (limited to the skin) to bone marrow transplantation for systemic sclerosis with internal organ involvement. Though there is no cure, advances are being made in the treatment of all manifestations of the condition. ...Read moreSee 1 more doctor answer
Scleroderma tests: The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even offer some predictions as to risks of certain types of complications. Anti rna-polymerase iii antibody, increases risk of renal crisis and sudden increase in blood pressure, antitopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension. ...Read moreSee 1 more doctor answer
Large range: There are numerous manifestations of scleroderma but the main feature is usually hard skin. This may be thickened hard skin in patches or around just a few fingers +/or toes or around the mouth. Others may have greater involvement of arms, legs causing difficulty moving joints. Worst are disfigurement of face and widespread tight skin over chest, abdomen. ...Read more
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