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Doctor insights on: Depression Wellbutrin Bupropion

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Dr. Pamela Pappas
4,598 Doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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How long can a person be treated for depression with wellbutrin (bupropion)?

How long can a person be treated for depression with wellbutrin (bupropion)?

Wellbutrin (bupropion): For first episode of depression, usually 6 months to a year. If recurrent, it takes longer. ...Read more

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Is it true that the depression med wellbutrin (bupropion) can help aid in u quitting smoking?

Yes: Bupropion, the generic of wellbutrin, (bupropion) is used for smoking cessation. Zyban has been branded for smoking cessation, and is the same generic. Since it is a prescription medication speak with your doctor for a comprehensive approach to smoking cessation using all the modalities available to you. ...Read more

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Can depression pills Wellbutrin (bupropion) SR cause Breast Cancer or any other Cancer?

No known connection: There is no known connection between Wellbutrin (bupropion) and BC. In fact, many oncologists prescribe specifically Wellbutrin (bupropion) a it's not an SSRI and works with dopamine instead. However, Wellbutrin (bupropion) affects the metabolism of tamoxifen, and should be avoided if you use tamoxifen. This is general information. Please consult your doctor for more specific answers, as they depend on your health history and so on ...Read more

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Hello I am on a high dose of citalopram 80mg for OCD, seen improvement in OCD not depression. Would adding Wellbutrin (bupropion) help?

Hello I am on a high dose of citalopram 80mg for OCD, seen improvement in OCD not depression. Would adding Wellbutrin (bupropion) help?

Need more info: Impossible to answer this question not knowing your medical & psychological history. Much better to talk it over with the physician who prescribed citalopram. ...Read more

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Got atypical depression. Gp prescribed wellbutrin (bupropion) but need to wait for 4 weeks to get the supply. Wt t do meanwhile to overcome oversleeping?

Got atypical depression. Gp prescribed wellbutrin (bupropion) but need to wait for 4 weeks to get the supply. Wt t do meanwhile to overcome oversleeping?

Talk to your doctor: Fatigue and oversleep is sometimes part of the symptom for depression. If you just start the wellbutrin (bupropion) it should take 4 to 6 weeks to improve the symptom. You could talk to your doctor add other medication to keep you alertness, such as Provigil or Nuvigil or other medication. ...Read more

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Severe health anxiety and depression. CBT and Wellbutrin (bupropion) and Lexapro not working. Can't sleep, can't stop worrying. What can I do? Life stinks.

Severe health anxiety and depression. CBT and Wellbutrin (bupropion) and Lexapro not working. Can't sleep, can't stop worrying. What can I do? Life stinks.

Regulation of habits: Besides the CBT, Wellbutrin (bupropion) & Lexapro try a notebook or tablet to track your daily routines like diet, sleep, regular meals, 7-9, 11-1, 5-7, enough sleep, exercise, dietary intake (calories), meditation, relaxation exercises, tai-chi, martial arts, prayer, anything that will help light up the frontal lobes if we would scan yours. It will take some time but all of the above will work over time. ...Read more

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I was diagnosed with severe depression. Put on colotopin, wellbutrin (bupropion) and a sleep anti depressant. It helped out tremendeously! I no longer have he?

I was diagnosed with severe depression. Put on colotopin, wellbutrin (bupropion) and a sleep anti depressant. It helped out tremendeously! I no longer have he?

Not sure: Unfortunately, I am not sure what you are asking. I am glad that your medications have been helpful. I think that you are asking if you should stop them now that you feel better. If this is your question, I would say NO!! You are probably feeling better because of the meds and when and how you stop taking them involves a decision between you and your doc. Discuss before acting. ...Read more

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I have GAD & depression Doc add me wellbutrin (bupropion) 150mg XL for sexual dysfunction It works very good for that but make me strong anxiety do I have to stop?

I have GAD & depression Doc add me wellbutrin (bupropion) 150mg XL for sexual dysfunction It works very good for that but make me strong anxiety do I have to stop?

SSRI/SNRI: Usually we treat anxiety disorders with antidepressant that have Anxiety modulating properties like the SSRI's and the SNRI's as well as the old generation of meds. Wellbutrin (bupropion) is not one of them. However we do combine Wellbutrin (bupropion) with SSRI's quite often to address depression and anxiety. Good luck and feel better ...Read more

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I am on inderal for hbp. Synthroid for hypothroidism. Zoloft for depression. And wellbutrin (bupropion). And started taling vitamin D3 supp. Any interactions here?

I am on inderal for hbp. Synthroid for hypothroidism. Zoloft for depression. And wellbutrin (bupropion). And started taling vitamin D3 supp. Any interactions here?

Yes: Wellbutrin (bupropion) and zoloft can increase Inderal level possibly leading to hypotension, slow heart beats. Zoloft and wellbutrin (bupropion) together might raise serotonin level increasing risk for serotonin syndrome. Close monitoring recommended. ...Read more

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How effective is Wellbutrin (bupropion) for treating depression?

How effective is Wellbutrin (bupropion) for treating depression?

Wellbutrin (bupropion): Works for some, especially for depression with low energy. ...Read more

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Is wellbutrin (bupropion) for ADHD and depression?

Is wellbutrin (bupropion) for ADHD and depression?

Wellbutrin (bupropion) is used: To treat depression. It is excellent for atypical depression. I have seen it used for adhd - but usually when more typical adhd medication were not an option. (off label). ...Read more

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Does wellbutrin (bupropion) help with depression?

Yes: It is best to speak specifically with you physician about your particular details. However, in general, wellbutrin (bupropion) can help treat a major depressive episode. Wellbutrin (bupropion) particularly helps when symptoms of low energy and poor concentration are present. The sexual side risk of wellbutrin (bupropion) are lower than other antidepressants. ...Read more

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I'm using Wellbutrin (bupropion) to treat depression, how do I tell if it's working for me?

Feel better but. .: Know that it make time for a medication to really "kick in" for you. As your body's neurochemistry has to adjust and/or the dose needs to be right for you. This can takes weeks if not months. But if it's going to work for you, you should feel some improvement in your moods, or energy levels, or desire to be active, or ability to concentrate. ...Read more

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Is wellbutrin (bupropion) good for depression and stopping smoking?

Yes 4 some: Some depressed pts & some smokers are helped by wellbutrin (bupropion). ...Read more

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Hat should I do if Wellbutrin (bupropion) is worsening my depression?

Hat should I do if Wellbutrin (bupropion) is worsening my depression?

Is it worsening it: Or just not ameliorating the symptoms? What is the dose, and for how long? What are the psychological events in your life? Is there a history of depression in the family, or during winter? Lots of questions--all should be asked by a psychologist or psychiatrist. Some meds actually cause the symptoms they purport to treat. You need an MD to assess that part. ...Read more

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How does wellbutrin (bupropion) (and similar meds) help with depression and anxiety?

Dep, usu not anxiety: Wellbutrin (bupropion) helps 2/3 to 3/4 of patients with clinical depression feel better, about the same as other antidepressants. It is not an anti-anxiety med, and won't help anxiety directly. However, sometimes anxiety is a symptom of depression. In this case, if the depression is treated the anxiety may go away as well. ...Read more

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Can wellbutrin (bupropion) and lithium improve anxiety, depression, and overal mood?

Can wellbutrin (bupropion) and lithium improve anxiety, depression, and overal mood?

Bipolar disorder: Bipolar disorder is often helped by lithium, which is a mood-stabilizing medication. Sometimes depression is severe enough despite this that an antidepressant like wellbutrin (bupropion) is added -- but not without the mood stabilizer. If prescribed by your psychiatrist and you are followed regularly, the combination may help your mood, wellbutrin (bupropion) is not an anti-anxiety medication, though. ...Read more

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I am currently on Wellbutrin (bupropion). Can I also take the herb Rhoziva to help with depression and managing stress?

Not a Good Idea: There is no scientific methodology to evaluate possible interactions between herbal supplements and medications that might be prescribed by a physician. As a result, information is based on animal studies, case reports, and historical contraindications. Rhozia, a herbal
supplement from Siberia increases dopamine/serotonin & might interfere with wellbutrin (bupropion). Avoid it. ...Read more

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Can one take a combo of Cymbalta and Wellbutrin? Cymbalta works well for my depression but Wellbutrin erased my alcohol cravings.

Cymbalta Wellbutrin: Cymbalta and Wellbutrin can be safely combined. The Cymbalta levels may be increased, but I have not seen this become a problem. The addition of Wellbutrin to SSRI antidepressants is a well studied augmenting method. ...Read more

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Can I take Wellbutrin (bupropion) XL 300 Mg for depression while pregnant? I came off of my meds after thinking that I could possibly be pregnant. What to do?

Consult your doctor: The vast majority of medications (including non-prescription and homeopathic, herbs, alternatives, etc) have the potential for causing birth defects. Therefore, first determine your pregnancy status then, consult your physician for whether you should be taking Wellbutrin (bupropion) if you are pregnant. It is rated Category C for pregnant women which means it's best avoided unless benefits outweigh risks. ...Read more

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Vyvanse and wellbutrin (bupropion) for add and depression, is that okay?

Vyvanse and wellbutrin (bupropion) for add and depression, is that okay?

Yes: Those two meds can be used together to treat those disorders. Unfortunately they will not overlap and provide benefit for both disorders. There is always the potential for some type of drug interaction or to just not feel well with both meds on board so it is importannt to have close follow up with the prescribing provider ...Read more

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Can I take wellbutrin 150 with Cymbalta (duloxetine) if im bulimic for depression?

Can I take wellbutrin 150 with Cymbalta (duloxetine) if im bulimic for depression?

PROBABLY NOT: There is an issue with the use of Wellbutrin (bupropion) in patients with bulimia due to a lowering of the seizure threshold. I hope that you are getting some help with a therapist as well. ...Read more

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How long should I take wellbutrin/zyban for depression once remission has been achieved?

How long should I take wellbutrin/zyban for depression once remission has been achieved?

It depends...: The conventional wisdom is for a patient with a first depressive episode, treatment should last for 6-9 months once remission is achieved because it reduces the risk of recurrence. However, if a patient has significant ongoing or anticipated stress (move, job change, etc.) or has a history of multiple depressive episodes, a physician may recommend the patient remain on medication for longer. ...Read more

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Can I take 10 mg of celexa with 150 mg of wellbutrin (bupropion) XL for anxiety and minor depression?

Can I take 10 mg of celexa with 150 mg of wellbutrin (bupropion) XL for anxiety and minor depression?

If prescribed, yes: If these medicines have been prescribed for you and you are being followed by a psychiatrist, you can take them. ...Read more

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May be far fetched but can plavix cause depression or reduced the effectiveness of wellbutrin (bupropion)?

It shouldn't: Plavix should just cause you to bruise easily. There is an interaction with Plavix and wellbutrin (bupropion). It can increase wellbutrin (bupropion) levels. Side effects of too much wellbutrin (bupropion) can be anxiety, tremor, insomnia, confusion and seizures. See your dr. If you are having any side effects. It is possible to take both medications and be monitored. ...Read more

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Why did my dr perscribe wellbutrin and zoloft for depression and anxiety. How do they work together? Is there much success rate with this combo?

Why did my dr perscribe wellbutrin and zoloft for depression and anxiety. How do they work together? Is there much success rate with this combo?

Different mechanisms: These two medications have different mechanisms of action and could have an additive effect without additive side effects. You should have posed the question to your doctor.
Exercise is a good treatment for depression. It is not easy getting started, but it is more than worth it.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex.
Get HPV vaccine. ...Read more

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I am on Wellbutrin (bupropion) and it was working really well, but this past month I've felt really horrible. Can anxiety/depression medications stop working?

I am on Wellbutrin (bupropion) and it was working really well, but this past month I've felt really horrible. Can anxiety/depression medications stop working?

See doctor: I'm sorry you're feeling worse. "Horrible" can't be assessed in this format. Does this mean feeling worse emotionally, have some recent upsetting events happened, do you have any physical symptoms as well? Best to review with prescribing doctor to reassess Wellbutrin (bupropion) dose or alternative med and consider seeing a mental health professional for support and guidance during this tough time. Take care. ...Read more

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Just started taking wellbutrin (bupropion) ir for depression. Also on plavix. Looking for a second opinion on dosage. What wb starting dose would you recommend?

Just started taking wellbutrin (bupropion) ir for depression. Also on plavix. Looking for a second opinion on dosage. What wb starting dose would you recommend?

Recommended dose: Recommended starting dose for wellbutrin (bupropion) immediate release is 100mg twice a day and for long acting 150mg daily. Dose is may be increased after about 3-4 days. ...Read more

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Will a rash from wellbutrin (bupropion) go away? As my body gets used to the medication? Rash is minor and I started about a month ago drug is helping depression

Will a rash from wellbutrin (bupropion) go away? As my body gets used to the medication? Rash is minor and I started about a month ago drug is helping depression

Wellbutrin (bupropion) rash: Please tell your doctor immediately about the rash -- it may be an allergic response that will not go away. If there's any possibility other factors are involved (new laundry detergent? Exposure to other allergens? Etc) it can be confusing. I would call my doctor today and not repeat wellbutrin (bupropion) dosing until you speak with your doctor or the on-call physician. ...Read more

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Taking 150 mg Wellbutrin for depression. First few months, experience side effects of lowered sex drive and appetite but now both are not only back to normal, but above normal. Is this indicative that I need higher dose?

Taking 150 mg Wellbutrin for depression. First few months, experience side effects of lowered sex drive and appetite but now both are not only back to normal, but above normal. Is this indicative that I need higher dose?

Curious: Your dose is low, not expected to help. It is rare for this medicine to influence sex drive or appetite at all. Perhaps it treated a lower sex drive and higher appetite that were actually a part of your depression. Even so, the low dose working is a surprise. I think that there are enough anomalies here that you are best served by meeting and reviewing in person with the prescribing doctor. ...Read more

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Does wellbutrin (bupropion) work very well for ADHD and depression?

Does wellbutrin (bupropion) work very well for ADHD and depression?

Wellbutrin (bupropion) is: Excellent for atypical depression/ seasonal affective disorder. Would not use it first line for adhd. However, it can be used off-label for that purpose. ...Read more

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I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

Drug Interactions: Elavil (amitriptyline) + Wellbutrin (bupropion) ^ es seizure risk. Escitalopram +amitriptyline ^'es risk of serotonin syndrome. Wellbutrin + Lexapro ^es seizure risk. I am assuming that the Elavil is added in for insomnia or pain control and not for depression/ anxiety. This does not mean that these drugs can't be used together but there are possible drug interactions. D/W your physician. ...Read more

Dr. Alan Ali
792 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


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