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Doctor insights on: Depakote Side Effects In The Elderly

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Hi docs, can you tell me if side effects are noticable on 250mg of divalproex/depakote?

Hi docs, can you tell me if side effects are noticable on 250mg of divalproex/depakote?

Depends...: It really depends on how your body metabolizes the medication. Most people do not report any side effects on such a low dose of medication. ...Read more

Dr. Jeffrey Cohen
249 Doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, . Etc. It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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What are side effects from the anticonvulsant depakote?

What are side effects from the anticonvulsant depakote?

Side effects: Both can cause nausea & headaches. Depakote side effects are tremors, inc. Weight, leg cramps, ataxia, swelling of face, hair loss, irregular menses in females, rash. Zoloft (sertraline) side effects are restlessness & diarrhea. ...Read more

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Side effects of depakote, do they go away?

Side effects of depakote, do they go away?

Sometimes: Some side effects go away, or at least get better, over time, and some do not. It sounds like you really need to discuss the situation in more detail with the person prescribing the depakote. ...Read more

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What is the definition or description of: side effects of depakote?

Mostly mild: Dyspepsia and/or weight gain are common. A rare side effect is a liver and blood allergy/dysfunction. Less common are fatigue, peripheral edema, acne, dizziness, drowsiness, hair loss, headaches, nausea, sedation, and tremors. An increase of ammonia levels in the blood, which can lead to vomiting and sluggishness. ...Read more

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Are there any long lasting side effects to an overdose of Divalproex (depakote) or Venlafaxine (effexor)? Provided that death does not occur.

Are there any long lasting side effects to an overdose of Divalproex (depakote) or Venlafaxine (effexor)? Provided that death does not occur.

Should resolve: But what prompts your question? Did YOU overdose?
If so, once all is destabilized, you should have no lasting damage. But discuss this with your doctor. ...Read more

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Side effects of Depakote and zoloft (sertraline)?

Side effects of Depakote and zoloft (sertraline)?

Side effects.: All psychiatric rx's have side effects. If you check with side effects in the pdr, you will not want to take another drug. Mostly, your individual should be concerned about the drug/drug interactions. It is almost unamerican not to be polymedicvated. The prescribing md should talk with the patient about what the drugs will do and more importantly what the drugs will not do. ...Read more

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Help! I know they say don't come off of Depakote urself but I have heard a lot say there were no side effects for them doing so. I also take seroquel (quetiapine)?

Help! I know they say don't come off of Depakote urself but I have heard a lot say there were no side effects for them doing so. I also take seroquel (quetiapine)?

Relapse vs withdrawl: While there are usually no side-effects, ie withdrawal, from stopping depakote, there is a very real risk of relapse. That is, the original problem that led to taking Depakote in the first place could return. Since Depakote is used for serious conditions, stopping this treatment without close monitoring by your doctor could be very risky. ...Read more

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My doctor increased my depakote dose to 1000mg is this considered a high dose and will the new dose add on more side effects than what I already have?

My doctor increased my depakote dose to 1000mg is this considered a high dose and will the new dose add on more side effects than what I already have?

Dose ok: This is not a very large dose A blood level will tell you if the dose is right side effects may be dose dependent, if they are not acceptable there are good alternatives to Depakote ...Read more

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I am worried about long term side effects of my bi-polar meds, depakote, Effexor (venlafaxine) zr as well been on them 12 years. What r the long term side affects?

It Depends: Many folks take Depakote and Effexor (venlafaxine) for years and years without any problems what so ever/ Depakote can have an affect on the liver, so it's good to have some blood tests every year or so. Also, Depakote can cause weight gain, and if a person gains too much weight, it can be associated with diabetes. Again, there's a test for that. With any treatment, one must weigh the risks and benefits. ...Read more

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I take Depakote for my bipolar 2 disorder will taking a mix of creatine and arginine have any side effects?

Why: Not sure why you would be taking arginine and creatine. Frolic acid and omega 3 supplementation are helpful. Any combination of medications prescribed or otc should be used with caution. Make sure you tell your doctor about all therapeutic substances you are taking so they can help monitor your mood and/or control of seizures depending on why you are taking depakote. ...Read more

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Discontinued Depakote after 20 yrs (seizure-free plus side-effects). Now anxious. I think because of gaba. Don't want benzos. Other ways to increase?

Discontinued Depakote after 20 yrs (seizure-free plus side-effects). Now anxious. I think because of gaba. Don't want benzos. Other ways to increase?

Gabapentin: There are other anti- seizure medications that might be more tolerable for you than Depakote that are also not benzodiazepines. Gabapentin (brand is neurontin) and its newer cousin, prefab akin (brand is lyrica) work on GABA and can be helpful for anxiety (off-label). Talk to your doctor about whether either of these might be appropriate choices for you. ...Read more

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Topamax, (topiramate) Sodium Valproate, Depakote and Lamictal, which are best for migraine aura, and which have the most side effects?

Topamax, (topiramate) Sodium Valproate, Depakote and Lamictal, which are best for migraine aura, and which have the most side effects?

Migraine: Prophylaxis with either Topamax (topiramate) or Depakote would be considered first line aggressive therapy (for males). With Depakote (sodium divalproate) we often see weight gain and a fine tremor (especially in older adults). With Topamax (topiramate) there are more side effects (weight loss, parasthesias, change in sense of taste, inability to sweat, glaucoma, kidney stones) www. Healthtap. Com/drericweisman ...Read more

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What are the side effects of taking divalproex drugs?

What are the side effects of taking divalproex drugs?

Depakote side effect: Divalproex is metabolized to valproic acid which can cause stomach upset. Higher doses can be associated with weight gain and tremors. The benefits for patients with bipolar, migraines and seizures are greater than most side effects pts have. I often will use lower doses to keep side effects down and add an additional med such as lithium to boost the benefits. ...Read more

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What are potential side effects of divalproex sod dr 250mg extended release?

What are potential side effects of divalproex sod dr 250mg extended release?

Side effects: Depakote side effects are tremors, increase Weight, leg cramps, ataxia, swelling of face, hair loss, irregular menses in females, rash. ...Read more

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Which has less side effects specially hair loss divalproex 500mg or topiramate 25 mg?

Which has less side effects specially hair loss divalproex 500mg or topiramate 25 mg?

Topiramate: Topiramate has a lower side effect profile. Howerver, divalproex may be more effective depending on the condition being treated. ...Read more

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Does propofol cause less side effects in the elderly?

Propofol: Propofol causes hypotension. All effects are dose dependent and patient dependent. Your anesthesiologist will adjust the dose based on multiple factors including age. ...Read more

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Any ideas on side effects of trimoptin in the elderly?

Any ideas on side effects of trimoptin in the elderly?

Trimethoprim: Trimpotin is a brand of trimethoprim sold in Ireland. Check out http://www. Drugs. Com/cdi/trimethoprim. Html for info regarding this antibiotic. Don't forget to check for drug-drug & drug-condition interactions. And ask about dietary supplement use, too. ...Read more

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Why do elderly people have more Ambien (zolpidem) side effects?

Why do elderly people have more Ambien (zolpidem) side effects?

Elderly people: Are gradually winding down due to the fact that aging gradually produces oxidative inefficiency in their cells. They have more side effects from any drug. ...Read more

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Are tylenol (acetaminophen) side effects different for the elderly?

Are tylenol (acetaminophen) side effects different for the elderly?

Lower dose: The maximum dose for Acetaminophen has gotten lower over the years, as there has been more liver problems related to it, at even what we though were 'safe' doses. The maximum dose is 2.4 gms a day and probably less for someone that is frail or who drinks alcohol (. ...Read more

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Should elderly take benztropine to help with td (mouth movements) side effects of antipsychotics?

Should elderly take benztropine to help with td (mouth movements) side effects of antipsychotics?

Maybe: Tardive dyskinesia (td) is an unfortunate side effect of long term treatment with antipsychotics. Benztropine may help with the tremors, but generally is poorly tolerated in the elderly due to sedation, confusion, constipation, etc. It is usually avoided if possible in the elderly. ...Read more

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Do the side effects of antipsychotic use (quetiapine) eventually go away after discontinuing? (uncontrolled mouth movements in elderly)

Do the side effects of antipsychotic use (quetiapine) eventually go away after discontinuing? (uncontrolled mouth movements in elderly)

Please: See your psychiatrist. The side effects you're referring to tardive dyskinesia can be treated pharmacologically. However there isn't a concrete answer regarding if this will remit if medication is discontinued. As always don't cease any medication abruptly and talk to the prescriber. ...Read more

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My daughter is five and weighs about 35lbs she takes 250mg of Depakote twice a day she also takes 75mg of guanaficine what are the side affects?

Guanfacine comes as: A short-acting one mg. Tablet (tenex), given 3-4 times a day. The long-acting form, intuniv, comes as 1, 2 & 3 mg tablets. The maximum dose is 4mg daily. Intuniv is approved for use in adhd. Optimal Depakote serum level are 50-100 micrograms/ml. For seizures & up to 125 micrograms/ ml for bipolar disorder. They should be used together with caution, as there is a potential drug interaction. ...Read more

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I know Depakote has a side effect of severe weight gain what is the percentage rate of people who have gained weight while taking it?

Dpk: I use departed a lot but probably less than I should due to weight gain. Most people don't gain weight on it, esp if they eat exactly the same on it than they ate off it. But my crude estimate would be 40% of people do. Sometimes those it is being used in are predisposed to the weight gain with little activity level or attention to food intake. 40% is my opinion, not from trials. ...Read more

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Bladder retention appeared when I began using Depakote in 1999. Never considered the cause--not listed side effect. Why continued when later listed?

Bladder retention appeared when I began using Depakote in 1999. Never considered the cause--not listed side effect. Why continued when later listed?

Yes it is reported: There was a study of 27, 713 patients who were Depakote users and 93 people that is 0.34%had urinary retention.
Urinary retention is reported by people with multiple sclerosis, depression, high blood pressure, pain and osteoporosis. ...Read more

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Started Depakote last week. Had my normal period 2 weeks ago, yesterday I started again. Is this a normal side effect of depakote?

Can be a side effect.: Irregular menses can be a side effect of depakote. I would be sure to use a good birth control method while you're on this medication. If you're irregular menses persist, then I would see your doctor to discuss it. ...Read more

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I've been sick with a flu time cold for 21 days today. I started a new med- depakote- I'm so tired, could this be the infection still or a side effec?

See below: Either a cold or flu should be better within 7-14 d. There is a possibility that you could have a sinus or lung infection-not uncommon complications. Depakote can make you tired as well & it's levels should be monitored. Please see your doc to see what's going on & to get you feeling better. ...Read more

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I recently starting taking Depakote 250 mg twice a day & Prozac (fluoxetine) 20 mg once daily I hear Depakote causes severe weight gain & weight gain is also a side effect of prozac (fluoxetine). Is this true?

I recently starting taking Depakote 250 mg twice a day & Prozac (fluoxetine) 20 mg once daily I hear Depakote causes severe weight gain & weight gain is also a side effect of prozac (fluoxetine). Is this true?

Weight gain: Yes, Depakote can cause weight gain, and some people also gain weight w/prozac. Not all do, though. It will be important to make sure you're exercising regularly, and be wise with your meals -- healthy, whole, nutritious foods and much less in desserts, etc unless you really did exercise that day. The good news is that exercise in itself is a useful treatment for depression! good luck to you. ...Read more

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I'm taking Depakote ER for bipolar and have had horrible insomnia, palpitations and tremors. Is this side effect or something else?

I'm taking Depakote ER for bipolar and have had horrible insomnia, palpitations and tremors. Is this side effect or something else?

Yes: Yes, those has been among possible side effects of Depakote er. Discuss it with the person who prescribed it to see if they want to change to other mood stabilizer unless you are getting to tolerate it. ...Read more

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Throat clearing from mucus. Possible side effect of Depakote OR Lamitcal?? (1875mg &200mg)2Ent's nasal scope neg. Have Nissen. History of asthma. Tried meds

Throat clearing from mucus. Possible side effect of Depakote OR Lamitcal?? (1875mg &200mg)2Ent's nasal scope neg. Have Nissen. History of asthma. Tried meds

Excess mucus: Thick mucus is a sign that your nasal cilia are not doing their job of moving bacteria out of the nose/sinuses properly. To correct poor ciia movevement
Drink green tea with lemon and honey
Use pulsed nasal/sinus irrigation at a rate for restoring cilia.
For the Hydro Pulse Nasal/ Sinus irrigator, add two teaspoon of Xylitol to the 500 ml basin, irrigate 2x a day until clear. ...Read more

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What effects does Depakote have on the human body?

Depakote: Some of the more serious effects include a severe skin reaction, weakness, easy bruising, lethargy, and confusion. Others include hair loss, vision changes, changes in menstruation, and GI upset. ...Read more

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Do some of the effects of Depakote on fetus wear off over time?

Avoid in pregnancy!: Depakote should be the last drug to be considered for epilepsy therapy in pregnancy because of its strong embryotoxicity and causal relationship with severe fetal anomalies (ranging from anencephaly and myelomeningocele to valproic acid embryopathy). ...Read more

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Can a person drinking alcohol everyday for 25yrs while on lithium and Depakote cause perm damage? What are the effects of Depakote mixed with alcohol?

Can a person drinking alcohol everyday for 25yrs while on lithium and Depakote cause perm damage? What are the effects of Depakote mixed with alcohol?

2 many variables: 2 many variables to answer specifically, accurately and comprehensively. Generally speaking, drugs (incl. Depakote and alcohol) with potential to have a negative effect on the same particular organ (e.g. Liver), will increase the risk of that negative effect when taken together. ...Read more

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Seizures caused from depleation of good sodium in my body. Caused from over medication of drug soma. Went into hospital, they brought sodium levels up through i.V's. Taking Depakote 500 mg. 1x per day to avoid seizures. Suggest support groups, effects on

It: It is probably true than anyone can have a seizure under the right conditions. These conditions include poisoning by prescription or recreational drugs, withdrawal from prescription or recreational drugs (including alcohol), brain injuries, general illnesses, and abnormal levels of blood salts (electrolytes -- including sodium). When people have seizures with provocation, they are not considered to have epilepsy, and usually don't require long term seizure medication.

People who have a tendency to have repeated seizures with little or no provocation have epilepsy. The diagnosis is made by history, and supported by results from tests like brain-wave recordings (eegs) and brain imaging (usually mri). Epilepsy usually does require long-term use of seizure medications like depakote, or other interventions like epilepsy surgery.

Taking Depakote for a provoked seizure is an unusual clinical approach. Depakote can be given for other reasons. Since Depakote use can be accompanied by serious short term and long term side effects, it is important to see a doctor to develop a better understanding for its use in specific cases. ...Read more

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How long take Depakote to be in your sistem?

Varies: On average it can take around 7-10 days for Depakote to reach a therapeutic level in your body. Depending on what you are taking it for, the desired clinical effect may take longer. ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more