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Doctor insights on: Depakote Er Medication

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Dr. Jeffrey Cohen
249 Doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, . Etc. It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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I was prescribed Depakote ER for my epilepsy! How do I know this medication isn't for me and I should stop taking?

I was prescribed Depakote ER for my epilepsy! How do I know this medication isn't for me and I should stop taking?

Please sit down &: Talk to your prescribing medical provider about your concerns. Are you having any severe side effects? Have you read something about it on the internet that scares you? Is the medication not effective at therapeutic dose? Best to discuss with your MD. ...Read more

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How different is divalproex vs Depakote er?

Duration: Depakote er is a branded drug which can be taken once daily. Steady drug levels are maintained, and adverse events may be lower due to lack of peaks in the blood stream. There are now generic forms of immediate release "depakote", but these must be used two or three times daily to achieve a consistent effect. ...Read more

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Taking Depakote ER for migraines and would like to stop. Is this safe?

Must be careful: Yes, it is safe- but keep in mind: This is normally done slowly. Depending on what dose you use, the amount you take is gradually reduced over weeks, to prevent the risk of a withdrawal effect, such as nausea or a seizure.

For example, if you use 500 mg twice a day, a typical reduction would be to 250 mg twice a day for one week, then 250 mg once a day for one week, then stop. ...Read more

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I'm afraid I might've had a stroke from Depakote er. Made me worry, would I ever be normal again?

I'm afraid I might've had a stroke from Depakote er. Made me worry, would I ever be normal again?

Get this checked: First, Depakote has loads of potential side effects, but, so far stroke is not one of them. Second, if you fear you had a stroke, see your doctor asap or head to hospital er if this is very recent. You are best advised to get help and find answers to your current problems. ...Read more

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What happens if someone were to take 100, 000 mg of Depakote er, 14 mg of lorazepam, 7 mg of reperidone,?

If you are having:
thoughts about killing yourself, get seen at the nearest emergency room now. Have a friend or relative drive you or call 911 for emergency services for transport. You can call the National suicide hotlines 24/7 at 1-800-suicide (1-800-784-2433) or 1-800-273 – talk (1-800-273-8255) for support.
...Read more

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Are there any vitamins or minerals that I should avoid while taking Depakote ER?

Depakote ER: Just eat good balanced diet, consult your doctor for supplements that you want to add, depakote ER may interact with several medications, even supplements. Take care ...Read more

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Could Depakote ER 1000 be split and does it cause muscle fatique?

Depakote: In general, not advise splitting slow-release or extended-release medications. The er is extended-release. ...Read more

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When is the best time to take valproate blood test to be most accurate level? I take 750mg twice a day (at 12h intervals) Depakote ER. Thanks

When is the best time to take valproate blood test to be most accurate level? I take 750mg twice a day (at 12h intervals) Depakote ER. Thanks

Trough level: Depakote ER is usually taken once a day because it is an extended-release formulation. Timing of the blood draw does matter. Speak to your prescribing physician regarding your dosing and blood work. Here is a relevant article with more specific information: http://www. Ncbi. Nlm. Nih. Gov/pubmed/16778728 ...Read more

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My doc told me today that it was okay to stop taking Depakote ER for migraines without a cut back plan. Taking it for a month. 1000 MG a day. Safe?

My doc told me today that it was okay to stop taking Depakote ER for migraines without a cut back plan. Taking it for a month. 1000 MG a day. Safe?

It may be, but: If you do notice any unpleasant effects you still want him to be responsible toward you. That's a reasonably brief use, but step-down is still done by many doctors. Ask for a 'security blanket' Rx for a step-down if you feel the need. You need not use it if you feel fine. Win-Win! ...Read more

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I went to a doctor for trouble sleeping and he put me on Depakote er. Did he lie about what it's for?

I went to a doctor for trouble sleeping and he put me on Depakote er. Did he lie about what it's for?

Misunderstanding?: Doctors rarely lie. But it does sound like you need to see another doctor. If you don't trust a doctor - even a good one - it's not as helpful. Make sure you understand each other - bring someone along to help if needed. It is not a usual rx for insomnia - it can even cause it. Understanding = help. Achieve it and you're partway there! ...Read more

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I'm bulimic and have been purging and taking laxatives. I haven't had my depakote er 750 mg for two days. Should it all be out of my system now?

I'm bulimic and have been purging and taking laxatives. I haven't had my depakote er 750 mg for two days. Should it all be out of my system now?

Bulimia: I feel your distress.
Purging and taking laxatives can affect your gastro-intestinal system.
Depakote is for seizure disorders, manic episodes and for prevention of Migraine
Its side effects can be— abdominal pain, Hyponatremia, loss/increased appetite, weight loss/gain, nausea, vomiting, diarrhea or constipation
Your Health is Precious!
Go to ER for Diagnosis, Consultations and Treatment. ...Read more

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Is Depakote ER safe for women who are pregnant or breastfeeding?

Is Depakote ER safe for women who are pregnant or breastfeeding?

No: Depakote (valproic acid) is a pregnancy category d, which means that the medication has been show to be associated with fetal abnormalities. Depakote has been shown to increase the risk if spina bifida (spinal defects), and other abnormalities.
Not recommended with breastfeeding. ...Read more

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Can I take ocassional acetaminophen 500-1000 mg if I've hepC, but liver tests are normal and I also take depakote ER 1000 mg/d.?

Can I take ocassional acetaminophen 500-1000 mg if I've hepC, but liver tests are normal and I also take depakote ER 1000 mg/d.?

Most likely: Although you should clear it with your liver doctor, occasional use of acetaminophen does not cause harm to the liver. If used on a regular basis, however, it can be harmful. Have you seen your doctor yet concerning treating your hepatitis C? Current treatments are much easier and practically free of side effects, and are much more effective. Check with your doctor. Good luck. ...Read more

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Is depakote er safe? I'm taking 500mg at bedtime. Is that considered a low dose for someone who is 143lbs? Taking it for Bipolar 1 Disorder.

Is depakote er safe? I'm taking 500mg at bedtime. Is that considered a low dose for someone who is 143lbs? Taking it for Bipolar 1 Disorder.

By it self: Yes. The drug level as well as CBC and LFT should be monitored periodically. Discuss other medications you are taking with prescriber and the possible interactions. ...Read more

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Lexapro, celexa, keppra (levetiracetam) xr, Depakote ER for racing thoughts, which is best?

Lexapro, celexa, keppra (levetiracetam) xr, Depakote ER for racing thoughts, which is best?

Racing thoughts: If the racing thoughts are from bipolar disorder, Depakote is probably the best. Keppra (levetiracetam) has been studied in bipolar depression, but the results have not been so good. Http://www. Ncbi. Nlm. Nih. Gov/pubmed/21034692 Lexapro and Celexa are both antidepressants which could worsen bipolar disorder if given by themselves without a mood stabilizer like depakote. ...Read more

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What to do if I went to a doctor about trouble sleeping and he put me on Depakote er. Did he lie about what it's for?

What to do if I went to a doctor about trouble sleeping and he put me on Depakote er. Did he lie about what it's for?

He may be: Attempting to improve your sleep by controlling an underlying mood disorder. I would ask the doctor the rationale directly. Take care. ...Read more

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I take Epilim Chrono 500mg which isn't actually equal Depakote ER. (500mg Epilim = 333mg sodium valproate + 145 mg valproic acid), so when to test?

Random: The idea is this medication is supposed to generate a steady state level after about 3 days. Peak and trough levels matter if you are looking for toxicity or sub-therapeutic levels with medications with a short half life. Also Depakote has a very wide therapeutic level (50-100)
Consider obtaining a Vit D level (which is often low) and checking ammonia after being on this medication a while. ...Read more

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Switched from Trileptal to Depakote ER 1000 mg/d ; I've HCV and Depakote itself is hard on liver, which pain killer should I prefer now? APAP or nsaids

Best ask prescriber: NSAIDS and acetaminophen (APAP, paracetamol) can both cause problems for someone with a damaged liver. Because a specific answer to a specific case would depend on detailed knowledge of medical history/labs/studies/biopsies, this question is best asked of the prescriber of the Depakote, or of the physician treating the hepatitis C. ...Read more

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I've chronic HCV, GERD, BP1 disorder. I take Depakote ER 1, 500/day, do I safely can take apap if I've fever, headaches, no longer than 5 days at 2 grams?

I've chronic HCV, GERD, BP1 disorder. I take Depakote ER 1, 500/day, do I safely can take apap if I've fever, headaches, no longer than 5 days at 2 grams?

Check LFT: You should check with your prescribing doctor regarding the status of your liver. I would periodically check liver function and ammonia anyway but I tend to err on the side of caution. The earliest sign of liver problems is loss of appetite followed by itchiness. I would not take more than 325 mg of APAP every 8 hours. ...Read more

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I'm taking Depakote ER for bipolar and have had horrible insomnia, palpitations and tremors. Is this side effect or something else?

I'm taking Depakote ER for bipolar and have had horrible insomnia, palpitations and tremors. Is this side effect or something else?

Yes: Yes, those has been among possible side effects of Depakote er. Discuss it with the person who prescribed it to see if they want to change to other mood stabilizer unless you are getting to tolerate it. ...Read more

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I have bipolar disorder I take medications zyprexa, (olanzapine) lamictal and Depakote 500 e.R and I smoked hash weed with medications sometimes I need an advice?

I have bipolar disorder I take medications zyprexa, (olanzapine) lamictal and Depakote 500 e.R and I smoked hash weed with medications sometimes I need an advice?

Bipolar Treatment: The research clearly shows that people suffering from bipolar disorder have the best outcomes with a combination of medication and psychotherapy. Psychotherapy should occur for an hour at least 1 or 2 times a month and sometimes more often during the course of treatment. Such treatment by good doctors can result in excellent outcomes. Smoking weed or hash is not associated with good outcomes. ...Read more

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Is Depakote a medication whose purpose is to reduce the pain?

Depakote: Is frequently used as a prophylactic agent for migraine, cluster and chronic daily headaches. It is indicated in the management of trigeminal neuralgia for those patients who are refractory to other medications. ...Read more

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What over-the-counter pain medication is safe to take after a D&C while taking Depakote?

Safe medication: You may take acetaminophen but not more than 4000 mg a day which would be 650 mg every 4 hours (that would make 3900 mg/day) or 1000 mg every 6 hours. Ibuprofen, naproxen and the like interact with Depakote by increasing the changes of bleeding (decreasing platelet count). Some people still take those together but under close supervision by their doctor. ...Read more

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They tried me the medication Depakote a year ago I still haven't been right still hsve some racing thOughts could it cause it I took it only a month?

Depakote->racing tht: It soundly like you've been diagnosed with anxiety and take Clonazepam and propranolol. It sounds like these should cover your anxiety. Given that you were only on it one 1 month, it does not seem it was likely the cause of your current racing thoughts. I'd schedule a follow up with your doc ASAP to determine what IS causing your racing thoughts and get these treated :) ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more