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Doctor insights on: Depakene Medication

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Is hair loss caused by medication (such as Lithium or Valproic Acid) generally reversible?

Is hair loss caused by medication (such as Lithium or Valproic Acid) generally reversible?

Yes: Alopecia (loss of hair) due to medications will reverse with stopping the insulting agent (the medication which caused it) The question is what to do if you need those medications to balance your moods, and function more adequately. Please consult with your prescriber to switch those mood stabilizers to another type, and use hair products to stimulate the growth and health of your scalp. ...Read more

Valproic Acid (Definition)

Valproic acid was the first product followed by valproex sodium (depakote, far less toxic). A drug approved by fda to treat migraine and/or epilepsy, and often used in psychiatry in addition. Very potent and valuable agent in view of broad spectrum benefits, but side effects and ...Read more


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Do any drugs exist for bipolar disorder that are not in the valproic acid classification?

Do any drugs exist for bipolar disorder that are not in the valproic acid classification?

Absolutely: For many patients, valroate has lots of side-effects, esp. Weight gain as well as others. Lithium, which is an element, is indicated for bipolar disorder. Other medications are carbamazapine (tegretol) and the medications in the class called second generation antipsychotics. A common problem with many medications can be weight gain issues. I always try to avoid this with my patients. ...Read more

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What is valproic acid?

What is valproic acid?

Several things: Valproic acid, aka-depakote, aka-sodium divalproex is classified as an anticonvulsant or anti-seizure medication. It is used for epilepsy, bipolar disorder-as a mood stabilizer, and is also used for migraine headaches. ...Read more

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How is valproic acid excreted?

How is valproic acid excreted?

In the urine: Valproic acid is metabolized in the liver by a number of enzymes, but is excreted in the urine. Less than 3 % is excreted unchanged as valproic acid. ...Read more

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How can you check a valproic acid trough?

Timing: A valproic acid trough level, which is what should be measured, needs to be drawn ten to twelve hours after the last dose. Btw-the therapeutic range for levels is 50-100 for seizures, but it is 75-125 for mood stabilization. Other labs which should be drawn with the level are a CBC (blood count), and ast/alt (liver enzymes). ...Read more

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What is the definition or description of: valproic acid?

Depakote: Valproic acid was the first product followed by valproex sodium (depakote, far less toxic). A drug approved by fda to treat migraine and/or epilepsy, and often used in psychiatry in addition. Very potent and valuable agent in view of broad spectrum benefits, but side effects and pregnancy risks very real. ...Read more

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What are the differences between valproic acid and lithium?

What are the differences between valproic acid and lithium?

Considerable: Although Depakote and lithium are both prescribed and are effective for the treatment of bipolar d/o, they do differ. Depakote is actually an anticonvulsant medication prescribed for seizures, while lithium is not. The latter is basically a mineral and considered a mood stabilizing medication. Lithium is metabolized through the kidneys, while Depakote is through the liver. ...Read more

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How long does it take for valproic acid to get in your system?

How long does it take for valproic acid to get in your system?

Medication effect: This is common question, most psych meds get quickly into your 'system' or blood and brain, but the effects are usually delayed often several weeks. Side effects occur when blood levels peak in a few days, but benefits can take weeks. So be patient. ...Read more

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Is it okay to take orlistat if you are taking valproic acid?

Categorically NO: If the valproate is for seizure control, I would definitely not recommend you take orlistat. Valproate is a prescription and should be given for a definite purpose. Orlistat is going to move things throug the bowel faster, inhibit fat absorption and can case mal-absorption of fat soluable vitamins in the diet. You end up pooping oil. If you do this, you should be under strict care of your doc. ...Read more

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Can you take nyquil with valproic acid medicine?

Yes: Shouldn't cause a problem but tell your doc you are doing it. ...Read more

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Differences between valproic acid & Sodium valproate?

Not important: There is a technical chemical distinction between them, but no important difference for patients. ...Read more

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What is a common reaction to Depakote / valproic acid?

What is a common reaction to Depakote / valproic acid?

Side effects?: Valproic acid is mainly used for the treatment of seizure disorders, bipolar depression or prevention of migraine headaches most important side effects are weight gain, occasional hair loss and ovarian cysts. It rarely causes fetal abnormalities (related to the development of the neural tube)in pregnancy. ...Read more

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What is the definition or description of: Depakene (valproic acid) allergy?

What is the definition or description of: Depakene (valproic acid) allergy?

STOP!!: What is the point in asking so many unhelpful questions and crowding the reply section when IF you really want to know the answer you can get it on the internet This service is for people who genuinely want reasonable answers not available elsewhere! ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Should valproic acid 1500 mg and sodium valproate 1500 mg be taken together?

Dr. Alan Ali Dr. Ali
2 doctors agreed:

Depakote: Not sure why u would be taking the same medication twice? . Also, make sure your blood level is therapeutic. ...Read more

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Valproic acid at low doses causing greater mental adverse side effects, and greater physical side effects at higher dosages?

Valproic acid at low doses causing greater mental adverse side effects, and greater physical side effects at higher dosages?

Dose related: Both mental and physical side effects with valproic acid are usually dose related (higher the higher the dose). However, you might notice that the effectiveness (reduction in mental symptoms) is also dose related. What you are thinking of as adverse mental side effects might be untreated psychiatric symptoms. Part of what makes psychiatry interesting! :-). ...Read more

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How effective is Valproic acid (Depakene) for treating epilepsy?

Very effective: Valproic Acid is a standard antiseizure medication, particularly used for primary generalized seizures and certain seizure syndromes. ...Read more

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Can I breastfeed my adopted infant while on depakene (valproic acid)?

Can I breastfeed my adopted infant while on depakene (valproic acid)?

Yes: Depakote passes through breast milk in humans. Although the full risks of taking Depakote during breastfeeding are unknown, most documented cases suggest there is little risk to breastfed infants. Many pediatricians consider Depakote to be safe during breastfeeding. Still, if your doctor recommends taking Depakote while breastfeeding, be sure to watch for any side effects. ...Read more

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Is 500mg valproic acid daily too low of a dose to even be therapeutic for a adult, to treat epilepsy?

Is 500mg valproic acid daily too low of a dose to even be therapeutic for a adult, to treat epilepsy?

Not necessarily: Depends upon what type of epilepsy someone has, and also upon how their unique brain chemistry reacts to the medicine. ...Read more

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Is it safe to use valproic acid in pregnancy?

Is it safe to use valproic acid in pregnancy?

Not recommended: This FDA Pregnancy Category D - so it isn't recommended. It can be associated with risk for significant risks to the fetus. ...Read more

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Are tremors common from epival/ depakote/ valproic acid?

Are tremors common from epival/ depakote/ valproic acid?

Absolutely!: I rarely prescribe valproate as an initial anti-epileptic agent anymore (though I did years ago) since there are so many aeds (antiepileptic drugs) that just as well or better without causing so many side-effects. Tremor is one of the chief offenders. Tremor can occur even at "sub-therapeutic" blood levels. ...Read more

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I am taking valproic acid and lamnet for seizures since last 3 yrs. Is there any long term side effect? Which meds should I avoid taking with these?

I am taking valproic acid and lamnet for seizures since last 3 yrs. Is there any long term side effect? Which meds should I avoid taking with these?

Probably not: Check with your neurologist and check what other meds you are taking.
Stay healthy.
I'm proud of you for being so careful. ...Read more

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Taking depakene (valproic acid) could this make me miss my period?

Depakote & period: Not likely, but please consult your Ob/Gyn. If Pregnancy test positive. ...Read more

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Is it safe to take depakene (valproic acid) while pregnant or breastfeeding?

Is it safe to take depakene (valproic acid) while pregnant or breastfeeding?

No: Can use while breastfeeding. If you are on this medication then you probably have a seizure disorder or bipolar disease. There is a risk of congenital defects but some women need to stay on this type of medication or else their original problem may worsen which would also be detrimental to the baby. You should start taking 1 gram of Folic Acid a day before you get pregnant while on this. ...Read more

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I take Epilim Chrono 500mg which isn't actually equal Depakote ER. (500mg Epilim = 333mg sodium valproate + 145 mg valproic acid), so when to test?

Random: The idea is this medication is supposed to generate a steady state level after about 3 days. Peak and trough levels matter if you are looking for toxicity or sub-therapeutic levels with medications with a short half life. Also Depakote has a very wide therapeutic level (50-100)
Consider obtaining a Vit D level (which is often low) and checking ammonia after being on this medication a while. ...Read more

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Is it safe to take fish oil while being on Zoloft (sertraline) 200mg and valproic acid 500mg?

Is it safe to take fish oil while being on Zoloft (sertraline) 200mg and valproic acid 500mg?

Yes: This is as safe as eating fish while on these- probably safer, as a good fish oil has been purified of mercury, pcb's etc.
Research studies show that adding fish oil to anti-depressants like zoloft (sertraline) often result in additional benefits (though some studies disagree). Fish oil is quite safe. See http://www. Drweil. Com/drw/u/qaa400988/fish-oil-for-depression. Html. ...Read more

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Currently on topamax (topiramate) as a mood stabilizer and it's not working for my bipolar type 2. I've already been on lithium, valproic acid. Any new ideas?

Currently on topamax (topiramate) as a mood stabilizer and it's not working for my bipolar type 2. I've already been on lithium, valproic acid. Any new ideas?

Yes: You have not been through all mood-stabilizing possibilities. If you're not working with a psychiatrist to manage these medications, please do so. Tegretol and Lamictal are 2 other options to consider. Also seroquel -- and latuda, (lurasidone) especially if you're very bothered with bipolar depression. Take care. ...Read more

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While on valproic acid (depakene), is it safer to use acetaminophen (tylenol) or ibuprofen (motrin)?

While on valproic acid (depakene), is it safer to use acetaminophen (tylenol) or ibuprofen (motrin)?

Check With Your MD: One should always check with their physician if they have specific questions regarding their medical care. In general, both Acetaminophen and Ibuprofen are safe to take with valproic acid. Taking more than 4000mg of Acetaminophen is not recommended due to liver toxicity. Patients taking valproic acid should have their liver function evaluated regularly by a simple blood test. ...Read more

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Chronic migraine... neurologist prescribed valproic acid, proponolol, flunarizine... these med make me v v sleepy whole day... cant go to work. Can I just try flunarizine?

Chronic migraine... neurologist prescribed valproic acid, proponolol, flunarizine... these med make me v v sleepy whole day... cant go to work. Can I just try flunarizine?

Discuss with Doctor: We can not advice you to stop any drug prescribed by your doctor. I suggest you discuss your concern about being drowsy with your doctor. Actually Flunarizine is what causes drowsiness as well as Valproic Acid and propranolol.All these drugs are used as preventive meds to prevent migraine attacks
Discuss your concern with your doctor and follow his/her advice ...Read more

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I have gained 40 kg while taking lamictal, seroquel (quetiapine) and valproic acid for my bipolar disorder, how can I lose that weight? Thanks

I have gained 40 kg while taking lamictal, seroquel (quetiapine) and valproic acid for my bipolar disorder, how can I lose that weight? Thanks

As above: Seroquel (quetiapine) and valproic acid, can cause weight gain, but the weight gain has to do with what u eat, how much u eat and how much u exersize, I have seen people gaining 5 lb and seen other gaining 20 lb. ...Read more

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My 11yr. Old is on valproic acid for seizure disorder, she is also on I'm amoxacillin. She has a bad cough can I give her cough medicine?

My 11yr. Old is on valproic acid for seizure disorder, she is also on I'm amoxacillin. She has a bad cough can I give her cough medicine?

See below: Professionally, I do not recommend cough suppressants except as a last resort for cough that has persisted to the point of not sleeping for multiple nights. Cough is protective and keeps your airways open as well as clearing mucous and other fluid from your lungs. Keeping the cough reflex is important. However, if the trigger of the cough is mucous drainage, using Mucinex (guaifenesin) and a sudafed can help. ...Read more

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My 5 yr son is under treatment with valproic acid due to febrile seizures. Dosage is 440mg/day and he weights 26kg. Is this dose correct?

My 5 yr son is under treatment with valproic acid due to febrile seizures. Dosage is 440mg/day and he weights 26kg. Is this dose correct?

Reasonable dose: This seems like a reasonable dose. This is on the low end of the scale. However you can go quite a bit higher. Ultimately, you need to weigh the risk of the medicine versus the benefit of preventing seizures. Please be sure you follow up to your doctor. ...Read more

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Taking valproic acid 250mg twice a day & fluoxetine 10mg once a day. Left arm feels heavy & hand shakes but right doesnt. What could it be?

Taking valproic acid 250mg twice a day & fluoxetine 10mg once a day. Left arm feels heavy & hand shakes but right doesnt. What could it be?

Get checked out: Weakness as you describe could be in related to the meds. Get it checked out to make sure it is not serious ...Read more

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Are the meds Chlorpromazine, Haloperidol, metoclopramide, phenytoin, valproic acid, &carbamazepine safe to eat to treat frequent hiccups. How long to take?

Are the meds Chlorpromazine, Haloperidol, metoclopramide, phenytoin, valproic acid, &carbamazepine safe to eat to treat frequent hiccups. How long to take?

Not all of them: Usually ALL those drugs is not not safe for hiccups. All those medications used alone have been used in the past for hiccups and are relatively safe though there may be some side effects. ...Read more

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What is a "medication HA"?

What is a "medication HA"?

I think: Medication headache....a type of frequent or daily headache. I'm not positive though. Need to see what the context the phrase was used. ...Read more

Dr. Tiffanie Noonan
40 Doctors shared insights

Depakene (Definition)

Depakene is an anti-migrane agent which is a kind of ...Read more


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