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Doctor insights on: Demerol Liver

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Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Liver damage from tylenol (acetaminophen) use?

Liver damage from tylenol (acetaminophen) use?

Question?: I'm not sure what the question is - if you are asking if tylenol (acetaminophen) can damage the liver, then yes. The fda recently decreased the maximum dose for tylenol (acetaminophen) to 3, 000 mg per 24 hours in healthy adults. For kids or those with medical problems, the dose is even less. Overdosing on the active ingredient in tylenol (acetaminophen) is one of the worst deaths i've ever seen. ...Read more

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I'm immune to the hydromorphone actions, but not other opioids such as demerol (meperidine hydrochloride) (meperidine) or morphine?

I'm immune to the hydromorphone actions, but not other opioids such as demerol (meperidine hydrochloride) (meperidine) or morphine?

Sounds confusing: In that hydromorphone is metabolized into morphine, and that is the effective agent in our bodies. There are people who may lack the enzymes to metabolize certain drugs, and this has been reported in some people with codeine, where the enzyme that metabolizes it to morphine is absent. It is possible you have something similar. Sometimes it is that you have not gotten the right dose by right route. ...Read more

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Safe antidiabetic in alcoholic liver disease?

Antibiotic: There are numerous antibiotics that would be safe. However, of course every illness has its own prescribed regimen. Also if a hepatic impaired patient does have to take a medicine that can impact their liver then often the dose is lowered and liver function is followed closely. ...Read more

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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Does cymbalta (duloxetine) cause fatty liver?

Not directly: Fatty liver comes from weight gain. The treatment is weight loss. If you gained weight while on Cymbalta (duloxetine) then indirectly it could cause fatty liver. It is not however any direct effects of the drug on the liver. Rather, it would be more of a direct effect of the drug on your appetite. Best wishes. ...Read more

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Is fatty liver dangerous?

Is fatty liver dangerous?

Absolutely-Cut Carbs: Fatty liver, especially from etoh & chronic hepatitis associated with cirrhosis (scarring throughout the liver & progressive liver failure, not reversible & leads portal hypertension, recurrent stomach./intestinal bleeding, feeling terrible & early death). Stop all etoh, get checked & txed for hepatitis & stop all carbs. Go lchf, see https://www.Healthtap.Com/#user_questions/810867. ...Read more

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Is fatty liver dangerous?

Is fatty liver dangerous?

Fatty liver dangers: Absolutely! It can be caused by a variety of things but each can cause cellular damage to the liver, then fibrosis, then even cirrhosis and liver failure. Obesity, pre diabetes and type 2 diabetes are causing non alcoholic fatty liver at an alarming rate, even in young kids. Prevention, early detection and treatment are key. ...Read more

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Taking hydrocodone for pain diagnosed nafld acetaminophen damaged liver would o xycodone be better be?

Taking hydrocodone for pain diagnosed nafld acetaminophen damaged liver would o xycodone be better be?

No, not necessarily: Oxycodone can also affect your liver. It can cause muscle spasms in your GI tract, including spasms of the sphincter of oddi, the opening of canals that lead from your liver ; pancreas into your small intestine. This can cause further injury to your liver. Drug levels can build up in your system, if u have prior damage. U should be followed closely by your dr. ; a pain management specialist. ...Read more

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Is paracetamol more toxic to the liver than opiates?

Is paracetamol more toxic to the liver than opiates?

A Tough Comparison..: (1) tylenol (acetaminophen) (paracetamol) is a direct liver toxin and had been a leading cause of acute liver failure in the U.S. & britain. (2) opiods, rarely, may cause idiosyncratic liver toxicity (a different mechanism) that may require relatively higher doses. Neither drug should be taken in excess of routine dosing guidelines. ...Read more

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Elevated lipase/amylase, no gallbladder, mrcp no infl of pancreas, liver lesion, not a drinker/smoker, only 32, was taking asacol (mesalamine) hd/colazal, opinion?

Elevated lipase/amylase, no gallbladder, mrcp no infl of pancreas, liver lesion, not a drinker/smoker, only 32, was taking asacol (mesalamine) hd/colazal, opinion?

See GI doctor: Its not clear whether you have pain / pancreatitis or how high your levels are. There's a lot of causes of pancreatitis including medicational side effect but it is best to have a GI doctor review your labs / imaging first. ...Read more

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Will blood tests show liver damage with narcotic addiction?

Will blood tests show liver damage with narcotic addiction?

Depends on chemical: It depends on the chemical and adulterants in the chemical that are being consumed. Often it may not be the chemical itself but other issues related to addiction, e.G, hepatitis, nutritional deficiencies, and concomitant alcohol abuse that may cause liver abnormalities. ...Read more

Dr. Steven Griggs
55 doctors shared insights

Meperidine Hydrochloride (Definition)

Meperidine hydrochloride is a drug that increases narcotic effects which is a ...Read more


Demerol (Definition)

Meperidine hydrochloride is a drug that increases narcotic effects which is a ...Read more