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Doctor insights on: Deep White Matter High Signal Intensity

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White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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Mri results Scattered punctate foci of incresead T2/FLAIR signal intensity are observed inthe subcortical and deep white matter, what it means?

Mri results Scattered punctate foci of incresead T2/FLAIR signal intensity are observed inthe subcortical and deep white matter, what it means?

It usually is an: Incidental age-related finding due to chronic microvascular changes, but not always. A few foci at your age are probably nothing to worry about. However, you need to talk to your doctor about what it means in your particular clinical situation. ...Read more

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When MRI show multiple foci of increased t2 weighted flair signal intensity in the deep white matter tracts, is nortriptyline 10mg the best medicine?

When MRI show multiple foci of increased t2 weighted flair signal intensity in the deep white matter tracts, is nortriptyline 10mg the best medicine?

Unclear: The findings you describe are radiological and generally don't represent active brain pathology. Infrequently they may associated with inflammatory processes or small vessel vascular disease. I would discuss it with a neurologist. Radiological findings are not usually treated unless there is a clear disease process associated with them. ...Read more

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I have MS, what does few scattered foci of increased T2 signal intensity in the white matter mean from an MRI report mean?

I have MS, what does few scattered foci of increased T2 signal intensity in the white matter mean from an MRI report mean?

Confirmation: If you have confirmed MS from other tests like a lumbar puncture and characteristic changes in your CSF, as well as clinical history that supports the diagnosis, then the foci of increased T2 intensity in the white matter may just be the areas in your brain that are being affected by the MS. Keeping track of these and their progression can help determine the progression of your disease. ...Read more

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Mr of the brain showed foci of abnormal highh signal in deep white matter?

Mr of the brain showed foci of abnormal highh signal in deep white matter?

High signal MRI: This finding in MRI of brain is non-specific.
Most of them are due to microvascular disease associated with high blood pressure and diabetes. Some due to old damage.
Also, can be seen in diseases such as multiple sclerosi.
Your doctor will decide if he or she should go further base on your sign and symptoms. ...Read more

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Few tiny foci of increased flair signal seen within the deep white matter of both cerebral hemispheres. Should I be concerned with this? Thank you

Few tiny foci of increased flair signal seen within the deep white matter of both cerebral hemispheres. Should I be concerned with this? Thank you

DETAIL OF MRI: This question is quite specific. You should discuss the results with the physician who ordered the test for you. ...Read more

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Hi, there are few small foci of high signal in the white matter of both cerebral hemisphere non-specific but likely ischemic. What does mean in MRI mr?

Hi, there are few small foci of high signal in the white matter of both cerebral hemisphere non-specific but likely ischemic. What does mean in MRI mr?

Review with Doctor: Usually a few small foci are of little concern, and merely mean that there is some small vessel disease, as occurs with high blood pressure, diabetes, or even with migraines. However, 26 is a pretty young age for age related changes, and should at least be viewed by your doctor. ...Read more

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CYSTS IN MAXILLARY SINUSES, RIGHT LARGER THAN LEFT OPACIFICATION OF MASTOID AIRCELLS PUNCTURE HIGH SIGNAL AREA SUBCORTICAL WHITE MATTER NASAL SEPTU?

CYSTS IN MAXILLARY SINUSES, RIGHT LARGER THAN LEFT OPACIFICATION OF MASTOID AIRCELLS PUNCTURE HIGH SIGNAL AREA SUBCORTICAL WHITE MATTER NASAL SEPTU?

Reason for MRI?: If this was supposed to be an MRI of the brain then, the read of the sinuses is a common "red herring" that radiologists always tend to comment on but rarely do the comments make it into the annals of CLINICAL SIGNIFICANCE nor do they ever have to do with the initial reason for which the scan was obtained. Bottom line is probably of no importance. But check with your doctor or neurologist. ...Read more

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Mri shows areas of altered signal in the periventricular deep white matter. Punctate and nonspecific... What does this mean?

Mri shows areas of altered signal in the periventricular deep white matter. Punctate and nonspecific... What does this mean?

It usually is an: Incidental age-related finding due to chronic microvascular changes, but not always. A few small foci are probably nothing to worry about. However, you need to talk to your doctor about what it means, if anything, in your particular clinical situation. ...Read more

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Whats my MRI results mean ? this was what summary said. a small non specific foci of increased signal intensty in deep white matter of both cerebral

Whats my MRI results mean ? 
this was what summary said.
a small non specific foci of increased signal intensty in deep white matter of both  cerebral

Probably nothing: Sounds benign. Ask your doctor. The doctor who ordered the MRI is ethically obligated to review the MRI with you and to interpret the findings as they relate to you specifically; or, if they can’t, to find someone who can. Remember that. ...Read more

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My 3 yr old had an MRI 2 weeks ago. Results states: "minimal nonspecific periventricular deep white matter intensities". What causes this? Prognosis?

My 3 yr old had an MRI 2 weeks ago.  Results states: "minimal nonspecific periventricular deep white matter intensities". What causes this? Prognosis?

Very Common: That is a finding that is commonly found in normal patients.

It does not seem like anything to worry about, although your 3-year-old must be having some serious problems if you needed a mri.

Periventricular white matter intensities are not a diagnosis, though. You have to keep looking. ...Read more

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Does an MRI result of "minimal nonspecific periventricular deep white matter intensities" correlate or rule out an autism diagnosis in a 3yr old girl?

Does an MRI result of "minimal nonspecific periventricular deep white matter intensities" correlate or rule out an autism diagnosis in a 3yr old girl?

Not correlation: Should discuss with the neurologist on what it likely represents. But I can tell you it is not known to have a significant correlation with autism by itself e.g this finding is a well-established determinant one way or another is not so. Take care. ...Read more

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What is deep white matter in the brain?

What is deep white matter in the brain?

I'll Try: You know that Hannibal movie where the guy's head was open you see brain hat you see is the grey matter. If you cut deep into a person's brain it looks more white, hence, the white matter. The fancy explanation, grey matter are the cell bodies and white matter are the axons (nerve wires). Your brain is arranged in a way where it just so happens to appear the way you see.?W ...Read more

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I was wondering about the possibility to have MS. MRI (0.3T, open) showed atleast 2 deep white matter lesions approx. 4 mm.

I was wondering about the possibility to have MS. MRI (0.3T, open) showed atleast 2 deep white matter lesions approx. 4 mm.

MS is a: Clinical diagnosis, not simply an imaging diagnosis. That said, and without the images or a more complete report, two 4mm white matter lesions would likely not be indicative of a high probability of MS. These types of findings are usually incidental, and increase in frequency with age. ...Read more

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Does a sroke in the left anterior cerebral territory and deep white matter cause central post stroke pain syndrome?

Does a sroke in the left anterior cerebral territory and deep white matter cause central post stroke pain syndrome?

Central pain: Central pain from stroke typically follows thalamic strokes. This part of the brain not in the anterior cerebral territory however this does serve the orbital frontal cortex that could in theory cause some changes in how your brain processes pain. Stroke in young adults requires an extensive workup including a hypercoagulable evaluation. The Best health. ...Read more

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What does scattered althought predominantely bilateral frontal, subcortical white matter punctuate foci of signal abnormality mean?

What does scattered althought predominantely bilateral frontal, subcortical white matter punctuate foci of signal abnormality mean?

Maybe nonspecific: If you have migraine, such white matter lesions are usually posterior, and if you had head trauma, the location may be more anterior, but both head and neck trauma could cause some increased foci. The demyelinating lesions of ms would be periventicular at right angles, but in the elderly such lesions might be c/w microvacular angiopathy, or even binwanger's. ...Read more

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Two MRIs both have shown "mild amount of signal hyperintensity in the periventricular white matter bilaterally." What could this mean?

The description: Is not very specific, and in the absence of clinical context, it is difficult to assess the significance. Most likely it is an incidental finding of little concern, but talk to your doctor about it. ...Read more

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Flair sequence demonstrates minimal increased signal in the periventricular white matter which is non-specific. What does this mean and can it be MS?

Flair sequence demonstrates minimal increased signal in the periventricular white matter which is non-specific. What does this mean and can it be MS?

Possible: If you have clinical abnormalities raising concern, this could be an early sign of MS. Best to see your neurologist and discuss this. Additional testing would involve possibly lumbar puncture, MRI of neck, and blood testing for other causes. Non-specific causes could include prior trauma, smoking, migraine, hypertension. ...Read more

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High anxiety about scattered white matter on mri. Have had anxiety issues for years. Ms symptoms and anxiety symptoms are simular. Should I worry?

High anxiety about scattered white matter on mri. Have had anxiety issues for years. Ms symptoms and anxiety symptoms are simular. Should I worry?

Get answers: Your description does not definitely rule in or out possibility that lesions are of MS origin. They may well be due to other problems, such as migraine, head injury, smoking, hypertension. Anxiety is NOT a cardinal sign of MS. Discuss fully with your doctor and decide the next steps. ...Read more

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I have 2 white matter brain lesions, pressure in head, fibromas,body pain, high white cell count, fever below 102,why is this all happening?

I have 2 white matter brain lesions, pressure in head, fibromas,body pain, high white cell count, fever below 102,why is this all happening?

Multiple causes: You will not identify a single cause for your symptoms / findings. Especially with identifiable lesions on your brain imaging, you need to be under the care of a competent specialist. ...Read more

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I have high calcium levels, brain MRI showed spots in white matter, pain on right side abdomin. Dr mentioned aphasia-can all these be realted? I'm 41

I have high calcium levels, brain MRI showed spots in white matter, pain on right side abdomin.  Dr mentioned aphasia-can all these be realted?  I'm 41

Possible: Exact scenario may be hard. Need ct of chest, abdomen, & pelvis to rule out any cancer that could cause high calcium or sarcoidosis. If not done, need parathyroid and vitamin d levels. It may be that you take calcium or Tums that increased your calcium in blood which is high enough causes confusion and weakness. If so, brain findings may relate to a virus possibly herpes vs others. ...Read more

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53 forgetful unsteady gait and shakes. TSH levels r slightly high and all cholesterol levels r high vit B /D low, CT showed atropy white matter chg?

53 forgetful unsteady gait and shakes.  TSH levels r slightly high and all cholesterol levels r high vit B /D low, CT showed atropy white matter chg?

B12: Needs to be maintained above 550 for at least 6 months before one would expect to see any recovery from the sensory ataxia (balance issues) I recommend use of methcyanocobalmine or sublingual B12. Memory problems take a while to recover as well. Low Vit D is thought to cause dementia as will hypothyroidism www.healthtap.com/drericweisman ...Read more

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My mri report — t2 and flair hyperintensities in a deep white matter distribution. What does this mean?

My mri report — t2 and flair hyperintensities in a deep white matter distribution. What does this mean?

That will depend: On your age. For example, if you are say 50 or older than one might say this is commonly found in that age group. On the other hand, if you are say 23 years old it is not common in that age group and has other meanings. It is therefore best to talk with your doctor ...Read more

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Minimal increased nonspecific signal in brain white matter. Unremarkable MRI of the brain. Can this be nothing in a 26 yr old?

Minimal increased nonspecific signal in brain white matter. Unremarkable MRI of the brain. Can this be nothing in a 26 yr old?

Yes: It can be nothing. Let's take a step backwards though. There must have been a reason for getting the MRI. Migraine headache can be associated with tiny punctate white matter changes. Perhaps a bit of clinical information and a look at the scan might be in order. If you can do this I would be glad to help. www.healthtap.com/drericweisman ...Read more

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Increased signal located in the "white matter adjacent to the posterior horn of the lateral ventricle" should I worry about this?

Increased signal located in the "white matter adjacent to the posterior horn of the lateral ventricle" should I worry about this?

Beware of this : It is not at all uncommon for this finding to be reported on a mri. Often the radiologist will say this could be due to "migraines, vasculitis, or lyme disease" it is very important that this result be interpreted by your doctor in the setting of your symptoms. ...Read more

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Okay should I worry that I have an increased signal located in the white matter adjacent to the posterior horn of the l lateral ventricle.

Depends. : We all get these as we get older. A few, small ones are typically not of any concern at your age. They increase with age and problems (blood pressure, cholesterol, diabetes, smoking, etc.). ...Read more