Doctor insights on:
Deep Brain Stimulation Treatment For Depression
Very Likely: Dbs is the surgical placement of electrodes on 2 brain sites, which are then stimulated by electric currents. A small study suggests that dbs might be helpful for 60% of people who get treated with it - which is a good result when you are treating treatment refractory cases. Due to its invasiveness meds, transcranial magnetic stimulation (tms), and ECT should probably be considered beforehand. ...Read moreSee 1 more doctor answer
Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more
No, but very helpful: Deep brain stimulation therapy of the stn (sub-thalamic nucleus) or gpi (globus pallidus interna) can greatly improve "on" time (good function with minimized symptoms) & greatly reduce dyskinesia (twisting, writhing, jerking movements during "on" time). Good candidates must be not demented, psychiatrically stable, & still demonstrating good symptom relief from meds, but with inconsistent results. ...Read moreSee 1 more doctor answer
Lukewarm option: Vagal nerve stimulation (vns) for treatment resistant depression is fda approved (2005). However, subsequent studies have not been too supportive of its use. There are many medication options and combinations these days as well as transcranial magnetic stimulation (less invasive) and electroconvulsive therapy (still an effective treatment). ...Read more
Does really ECT causes memory loss and is transcranial stimulation effective option for anxiety and depression?
Tx options: ECT can cause loss of recent memories. Transcranial magnetic stimulation (TMS) uses magnetic fields to stimulate brain nerve cells to treat depression. Cranial Electrotherapy Stimulation (CES) uses a pulsed electric current across the head to treat depression, anxiety & insomnia. I use CES with a large number of my patients with good results. ...Read more
Experimental: DBS of Cingulate Gyrus area 25 of the brain with electrodes has demonstrated positive benefits for some very depressed folks. The treatment is surgery, however, and is still classed as experimental. What constitutes a good candidate varies, but usually includes refractory response to other methods and a reasonable health status to survive surgery. Not enough is yet known for longterm effects. ...Read more
What are your thoughts on deep brain stimulation as a treatment option for patients with alzheimer's disease?
Great potential: This is an area of intense research in neurosurgery. There are some early clinical trials being done at this time (hopkins) that are showing some efficacy. The molecular mechanisms are being investigated in the laboratory and are very promising. Dbs in the treatment of patient's with alzheimer's disease is a topic to be watched. ...Read moreSee 2 more doctor answers
Which results have patients experienced from deep brain stimulation for the treatment of Parkinson's disease?
Parkinson's disease: Deep brain stimulation (dbs) for parkinson's disease reduces the tremors, rigidity, and slowness of movement. The dbs does not destroy the surrounding brain, can be programmed with an external computer, and can be turned on and off. The dbs also allows patients to reduce the intake of oral medications. ...Read more
Possibly: Gamma knife surgery is actively being studied as an alternative choice to traditional epilepsy surgery. Deep brain stimulation of the thalamus has been studied and has been found to be an effective therapy for some types of epilepsy. However, it may not offer any advantage over the vagus nerve stimulator, which is a less invasive treatment. Right now, insurers do not cover dbs for epilepsy ...Read more
We don't fully know: But the wires are placed into deep basal ganglia nuclei and the electrical impulses stimulate the electrochemical discharges and basically help management of fluctuations and varying symptoms. One item of interest is absence of benefit if unresponsive to L-DOPA, so, obviously, this is one potential explanation, but not all to it. ...Read more
Is deep brain stimulation being used for major depressive disorder? Is it like ect of years past?
Some Confusion: Electro convulsive therapy (ect), repetitive transcranial magnetic stimulation (rtms), and deep brain stimulation (dbs), are used in the treatment of major depression. Only ECT and rtms have fda approval. In ECT an electric charge is passed through the brain, in rtms strong magnetic fields are created in areas of the brain, and with dbs implanted electrodes deliver electricity to the brain. ...Read moreSee 1 more doctor answer
Actually, : I have met patients who are in their 40's and 50's who have had the procedure. The more we learn, about dbs, and the more cases of parkinson's presenting earlier, suspect we will be utilizing variations of dbs sooner in the disease course. But cannot get success in pts who do not respond to l-dopa. ...Read moreSee 1 more doctor answer
What percentage of Parkinson's disease patients are good candidates for deep brain stimulation (DBS)?
Parkinson Diseases: DBS is typically reserved for patients with end stage type disease that failing medications. It is not a first line type of therapy. ...Read more
Deep brain stimulators are used in the treatment of parkinson's and tremors. A person is scanned with a MRI or ct frame on their head. A burrhole is then made and a stimulator wire is passed into a precise deep brain target. This is connected to a stimulator which placed under the skin. They are very expensive but ...Read more
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