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Doctor insights on: Decreased Wbc With Lupus

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have  recurring flares of  rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back.  My ANA is 6:40.  I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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White Blood Cell (Definition)

Body blood cell that responds to inflamation or infection or ...Read more


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Is it normal for ones WBC to drop below normal (3000) when on 15 mgmethotrexate weekly? Or is it more likely combo of disease itself (lupus) & methotr

Is it normal for ones WBC to drop below normal (3000) when on 15 mgmethotrexate weekly? Or is it more likely combo of disease itself (lupus) & methotr

See below: It can occur with either of the above. However; your Methotrexate dose may need to be reduced because of the lower white blood cell counts. Discuss with your rheumatologist. ...Read more

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Does lupus cause high WBC count?

Does lupus cause high WBC count?

No.: In fact a low lyphocytes count heralds an increase in lupus activity, and neutropenia is common in sle! a high white count means inflammation usually infectious. Steroids like Prednisone will elevate it. Smoking will, as well. ...Read more

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Is a high WBC count attributed to lupus in any case? I understand they are typically low.

No: If one has lupus and a high white count it is usually due to infection or use of prednisone. It is not related to uncomplicated lupus. ...Read more

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On15mg methotrexate weekly for lupus. It is normal for WBC to vary much (8.0 e3/ul one week, 2.0 e/ul the next? Is that normal for normal person?

See below: That is a little unusual for the counts to vary that much in two weeks time. If the counts were drawn further apart, a decrease in the white blood cell counts could be explained by an increase in Methotrexate dose, viral infections, or reduced clearance from your body due to kidney weakness. Depending on the above, your doctor may reduce your dose of methotrexate. Hope that helps. ...Read more

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On methotrexate for lupus. I tend to feel great when my WBC is below normal range (2000) & have symptoms when it's normal (8000).Why?Is that common

See below: When you lowering your white blood cell counts that low, you are reducing inflammation as inflammatory cells associated with your disease. However; to reduce your cell count to that level puts you at considerable risk for infection and other complications. Your rheumatologist can come up with other options for you that will hopefully not lower your white blood cells counts down that much. ...Read more

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I have discoid lupus not sle. Could this make WBC fluctuate?

I have discoid lupus not sle. Could this make WBC fluctuate?

DIscoid Lupus: Absolutely it can. Some people progress to sle from discoid lupus. And discoid is an autoimmune condition that can have effects on bloodwork. ...Read more

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I am 37 female and I have sle lupus among other things I have pain all over. I went to the ER last night they found high wbc. S.O.S. Helpless?

Maybe nothing.: Talk to your rheumatologist or primary care doctor first. Some people always have a little bit of a high WBC and some medicines (including those used for lupus) can raise the white blood count. Don't be alarmed by a number. Let your doctors be if appropriate. Call them in the morning. ...Read more