Doctor insights on:
Decreased Wbc With Lupus
I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?
Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read moreSee 2 more doctor answers
My WBC is 2000 consistently. I have lupus. Could that be "normal" & non concerning for an average person, or just "normal" in someone with lupus?
With lupus, could being in the sun too much and getting flare symptoms for few days cause the WBC count to drop to slightly below normal?
On15mg methotrexate weekly for lupus. It is normal for WBC to vary much (8.0 e3/ul one week, 2.0 e/ul the next? Is that normal for normal person?
See below: That is a little unusual for the counts to vary that much in two weeks time. If the counts were drawn further apart, a decrease in the white blood cell counts could be explained by an increase in Methotrexate dose, viral infections, or reduced clearance from your body due to kidney weakness. Depending on the above, your doctor may reduce your dose of methotrexate. Hope that helps. ...Read more
On methotrexate for lupus. I tend to feel great when my WBC is below normal range (2000) & have symptoms when it's normal (8000).Why?Is that common
See below: When you lowering your white blood cell counts that low, you are reducing inflammation as inflammatory cells associated with your disease. However; to reduce your cell count to that level puts you at considerable risk for infection and other complications. Your rheumatologist can come up with other options for you that will hopefully not lower your white blood cells counts down that much. ...Read more