Doctor insights on:
Why?: Why are you on DDAVP (desmopressin) and why do you want to wean off it? I only treat diabetes insipidus (not the other uses - enuresis and von Willebrand's disease). I'm guessing DI. Why would you want to stop the drug? If you have DI and a normal thirst mechanism with ad lib access to water, you'll survive, but your quality of life will suck. I hate making assumptions though. ...Read more
Neither: The medication actually decreases urine production by mimicing a natural hormone we make to help us hold on to water when we are not drinking much. Once the medication exits the body, the effect is gone and you make as much pee as you would normally.By cutting down on night urine production it helps some kids stay dry through the night.It doesn't cure anything. ...Read more
Manmade v. natural: Vasopressin is the human produced hormone, while the long-acting synthetic analogue of this is desmopressin. But they have very similar effects -- although nothing is as good as the body's own creation. Vasopressin controls blood osmolarity (volume of urine, volume of blood and fluid in the body). ...Read more
Reduce urine amount: It is a synthetic anti-diuretic hormone. Acts on the kidney to reabsorb more filtered water so that less urine is produced. Idea being that the bladder will be able to accomodate a smaller urine volume produced and not reach a threshold where nervous system feels it has to expell urine, whilst subject is sleeping, and result in control of bedwetting. ...Read more
No: Desmopressin is the drug form of a hormone called Vasopressin, secreted from the brain, and which works in the kidney to control fluid balance in the body. It has no value in terms of curing neurogenic disease. It's secretion can be affected by neurologic issues such as head trauma, brain tumor, or brain surgery, depending on the area of the brain affected. ...Read more
Think my dr. incorrectly diagnosed me with CDI when I actually have NDI since DDAVP (desmopressin) hasn't worked after increasing dose to 1 mg/night. What to do?
Second opinion.: If you ever find yourself questioning a diagnosis given to you by one doctor, a second opinion with a local doctor or with one of us here on HealthTap would be a wise idea. ...Read more