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Doctor insights on: Dcp Des Gamma Carboxy Prothrombin

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High prothrombin time levels affect bleeding?

High prothrombin time levels affect bleeding?

Yes.: Prothrombin times about three times higher than normal for the particular lab may be a risk for abnormal bleeding. ...Read more

Diethylstilbestrol (Definition)

It was mistakenly used in the past (until 1971 in the us) to prevent miscarriages and premature delivery. It was later recognized to increase the risk iof certain cancers in mothers and babies exposed to it, as well as causing abnormal development of sexual organs ...Read more


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What is the difference between thrombin and prothrombin?

What is the difference between thrombin and prothrombin?

Activation: Prothrombin{ II } is converted to Thrombin {IIa} ,the active form of the clotting enzyme by activated factor Xa and cofactor Va . This is the final common pathway for thrombosis. Thus Thrombin is just activated prothrombin. ...Read more

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What is thrombocytopenia and how is a prothrombin time test used?

What is thrombocytopenia and how is a prothrombin time test used?

Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time. ...Read more

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If a partial thrombin time is high will the prothrombin also be high?

If a partial thrombin time is high will the prothrombin also be high?

Not always: U mean: PTT vs. Pt? The partial thromboplastin time (PTT) measures the intrinsic pathway of the coagulation cascade; the protime (pt), the extrinsic. The pt is commonly affected by vitamin k antagonists (think: coumadin); the ptt, by heparin. Clotting factor deficiencies may also prolong both pt and ptt, but formal hematologist testing is required. ...Read more

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My prothrombin time is 15.7. Will that be a problem if I have major surgery?

My prothrombin time is 15.7. Will that be a problem if I have major surgery?

Prothrombin time: An elevation in the Prothrombin time should be evaluated before you have surgery. There are many possible causes for this and it could pose a risk for you during surgery. ...Read more

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What types of drugs an foods interfere with the coagulation test of prothrombin time?

What types of drugs an foods interfere with the coagulation test of prothrombin time?

Depends on : Circumstances. In a normal person, usual drugs and foods do not affect pt measurably. In patients on warfarin, foods both prolong pt, e.g., grapefruit, or shorten it, e.g., green leafy vegetables. Many drugs affect pt, e.g., birth control pills, isoniazid, anti-fungals, antibiotics, and many other drugs metabolized through cytochrome p450 system, and barbiturates and alcohol. ...Read more

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What is prothrombin?

What is prothrombin?

Clotting factor: When activated, prothrombin becomes thrombin, which among other effects turns fibrinogen into the stick for fibrin to create a molecular meshwork that will become the basis for the scab. Protrombin time is a conventional name for one assay of the ability of the clotting factors (not platelets) to keep blood in the vessels. ...Read more

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What does a prothrombin time measurement do?

Extrinsic pathway of: Clotting. Pt is dependent on levels of multiple coagulation factors, including x, ix vii, v, and ii. ...Read more

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Decrease in prothrombin time can lead to what?

Decrease in prothrombin time can lead to what?

Repeat test.: A shortened clotting time that does not appear to reflect technical error has been associated with an increased risk of thrombosis, recurrent thrombosis, recurrent miscarriage, or bleeding, and may increase the risk of thrombosis associated with other common thrombotic risk factors (eg, factor v leiden, obesity, increased levels of d-dimer). ...Read more

Dr. Shimae Fitzgibbons
209 doctors shared insights

Prothrombin Time (Definition)

Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used ...Read more