Doctor insights on:
Restate question: Hi jsalyers9. Can you restate your question with a little more information. What is being treated? What treatments have already occurred? Thanks. ...Read more
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
While gefitinib was: Developed first, it is hard to find in america (iressa (gefitinib)). Erlotinib (tarceva) has more side effects, but a trial showed a survival advantage. Probably more related to the characteristics of the study participants than the drug. These are small molecule, tyrosine kinase inhibitors in the erb family of receptors. Canada and europe has iressa (gefitinib). Erlotinib is in us. ...Read moreSee 1 more doctor answer
Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
Mult.Myeloma relapsed after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?
Fever could be side : Effects of the chemotherapeutic agents and steroids considering there's no blood infection. Tylenol (acetaminophen) should help control the fever. Follow up with your oncologist. God bless you! http://www.Livestrong.Com/article/36171-herbs-cancer/. ...Read moreSee 1 more doctor answer
If avodart & flomax are cy3a4 substrates & sprycel (dasatinib) is an inhibitor, why do interaction checkers show a prob. With sprycel (dasatinib) & avodart but not w/flomax?
Good Question: Avodart (dutasteride) is extensively metabolized in humans by the cyp3a4 and cyp3a5 isoenzymes. Flomax (tamsulosin) is extensively metabolized, mainly by cyp3a4 and cyp2d6 isoenzymes. Sprycel (dasatinib) is also extensively metabolized by the cyp3a4 isoenzyme but is also a weak time-dependent inhibitor of cyp3a4 and may therefore potentially increase the concentrations of Avodart and flomax. ...Read more
Type of Leukemia?: More details are needed to answer this question, specifically what is the leukemia type? Is it acute lymphoblastic leukemia, chronic lymphocytic leukemia, or are you referring to chronic myeloid leukemia? Please ask this question again with the additional information so it can be answered. ...Read more
What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?
Other drugs worked: Nexavar, torisel, and sutent all received FDA approval because they improved progression free survival. The initial Trovax trial was terminated early because there was little or no prospect of demonstrating a statistically significant survival benefit compared to placebo. http://clincancerres.aacrjournals.org/content/16/22/5539.long ...Read moreSee 1 more doctor answer
These are 2 options: Xeloda (capecitabine) - is an oral chemotherapy drug that can be used for certain metastatic cancers alone or in combination with other chemotherapy drugs as palliative treatment. Zometa - is used in a situation where cancer has spread to the bones. Its not chemotherapy but a bisphosphanate, a medication used to prevent further weakening of bones by cancer and prevent fractures. In some situations both are given. ...Read more
Targeted therapy: It is a targeted therapy. It is an oral tyrosine kinase inhibitor pill that targets part of the egfr pathway. Recently we have learned that there a several gene mutations that are found in lung cancer. If a patient has a mutation of the egfr system that their lung cancer developed, this drug can be more effective than chemotherapy in controlling their cancer. ...Read more
Usually average 1 cold per year. None since began taking Sprycel (dasatinib) for CML 4 years ago. Do these TKIs have antiviral properties?
Congratulations: Dasatinib, like imatinib tyrosine kinase inhibitors are great success in cancer treatment for CML etc.Suppressing abnormal white cells defective in combatting infections may have enhanced your body's normal white cells against colds,etc. These molecules block the TKI molecular switches on cells. They do not have antiviral properties. That said, side effects of TKIs include low blood count,takecare ...Read more
- Talk to a doctor live online for free
- Causes of sleeping a lot
- Sudden pain in eye while sleeping
- Is dehydration a symptom of urinary tract infection?
- Ask a doctor a question free online
- Blood pressure symptoms
- Is painful urination a symptom of genital herpes?
- Is back pain a symptom of placenta accreta?
- Is melasma a symptom of systemic lupus erythematosus sle?
- Dasatinib medication