Doctor insights on:
Dangerous Bilirubin Levels
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
Just a number.: In and of itself, the bilirubin level is just a number, and as such your number os not very high. It would be prudent, though, to interpret this value with respect to your other liver enzyme values — LDH, AST, ALT, GGT — as well as perhaps a liver ultrasound. Low value, but hard to interpret on its own. ...Read more
Safe: The only danger in "gilbert's" is that someone will misunderstand / overdiagnose / overtreat. Very rarely, gilbert's people run into trouble with a few medications; your physician will be aware of this. It should be called "gilbert's non-disease". ...Read more
My bilirubin levels are total 1.12,direct 0.16 and indirect 0.96. It is specified that indirect bilirubin should be within 0.0 to 0.6. Is it dangerous?
Whoa: First, this is a very low top for the reference range for indirect bilirubin. Second, reference isn't the "should be" range, but a measure of a population, set so that several percent of healthy people will fall outside. Third, I've raised my indirect bilirubin by hemolsis from strenuous exercise. You might also have Gilbert's. If you have no other indicator of ill-health, forget about this stuff ...Read more
It is all relative!: If the Cancer is involving your liver, then rising bilirubin is an indication that your tumor in the liver is quite large and progressive. This needs an aggressive search for the exact cause(?obstruction of the bile duct) which may be correctable. Ask your oncologist if he can do a local treatment for the bulky tumor.....something like SBRT or an ablative treatment(which can still be useful) ...Read more
I had a laproscopic surgery for gall bladder stones&now my bilirubin level is12. I went for scan, its result is mild hepatomegaly, is it dangerous?
Possibly: If you just had the surgery or recently it could be that they cut your bile duct, occluded your bile duct, or you have a leak from the liver. A ct scan will show fluid collections to determine if possible leak. You need to look at indirect bilirubin to know if it is obstruction. I would rule those out first and if negative the liver needs to be evaluated maybe biopsy, see your surgeon. ...Read moreSee 1 more doctor answer
Depends: It depends on the age of the patient and the level of the jaundice. Jaundice in adults is not as dangerous in that the bilirubin (which causes the jaundice) is not damaging, but it can indicate a condition that is (liver failure.) in babies, a high level of bilirubin can lead to a condition where the bilirubin gets into the brain and causes permanent damage to the developing brain cells. ...Read more
Bilirubin: Elevated bilirubin can result from two main sources-- breakdown of hemoglobin (from red cells) and blockage of normal secretion from the liver (obstruction of a bile duct.) These two sources are distinguishable in blood (bound vs. unbound.) Get more information and correlation of type of bili to be sure. ...Read more
More than ~1.5 mg/dL: Or thereabouts. Whether it means anything is another story. Folks with gilberts hover between here and maybe 3-4 without being sick. Folks who have hemolysis from illness or extreme athletics run a high bilirubin that's well tolerated. Liver disease and bile duct obstruction are likely to raise bile salts and the jaundice is thus more unpleasant. ...Read more