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Doctor insights on: D Dimer Test

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What is a ?D-dimer test?

What is a ?D-dimer test?

Thrombosis: The d-dimer is a fibrin degradation product (or fdp) which represents a small protein fragment in blood after a blood clot is broken down. The value can be used to test for clotting or thrombosis problems. However, a single value or a value in isolation should not be used. ...Read more

Dr. Jeff Livingston
14 doctors shared insights

H. Pylori Breath Test (Definition)

H.Pylori urea breath test is used to detect the presence of h.Pylori in the stomach. If present it acts on urea and releases carbon die oxide (co2)and ammonia. The released co2 is measured, and the presence of h.Pylori is confirmed. It is a useful test conducted in about 15 minutes. The sensitivity and specificity of ubt are approximately 88 to 95 percent and 95 ...Read more


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Purpose of a d-dimer test?

Purpose of a d-dimer test?

Clotting disorders: D-dimer is a small protein fragment present in the blood after a blood clot is broken down by the naturally occurring process of clot breakdown, called fibrinolysis. D-dimer levels are determined by blood tests and elevations can be seen in conditions of blood clots, such as with deep vein thrombosis, with severe infections and with advanced liver disease (which normally clears d-dimer). ...Read more

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D-dimer test results over 1000, even 1500.?????

D-dimer test: D-dimer uses antibodies to detect certain portions of the fibrinogen molecule that has been cross-linked, indicating that it was part of a clot. When elevated it means that two things have happened- clot formation, and at least the beginnings of clot break-up (lysis.) But it doesn't tell one where the clot came from or may have gone. Also, after surgery, #s can be high, so clinical setting matters ...Read more

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I had the d-dimer test done and it came back 826. Is this worrisome?

Not enough info: Ddimer is a breakdown product of clot (fibrin). It may be normally elevated in a variety of situations and not be indicative of underlying disease. It must be interpreted with caution due to variability in the assays used and the sensitivities of the tests. A hematologist is the best to answer your questions. ...Read more

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Dr. Tso Chen Dr. Chen
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Hi, Is the D Dimer test when combined with low probability really reliable? I know of the research suggesting between 96-99% npv but in a clinical setting is what you have experienced? Thanks

Dr. Tso Chen Dr. Chen
1 doctor agreed:

Reliable: If the clinical pretest probability of VTE is low by calculating the Well's score, the use of D -dimer in this case has a very high negative predictive value. I have used this rule quite frequently in clinical practice, and it's highly reliable. Just curious, are you a medical resident or in the medical field? ...Read more

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How good is a d-dimer test at detecting clots.

How good is a d-dimer test at detecting clots.

Depends: This test has a very high false positive rate and is used primarily to rule out the presence of a clot. Just because the d-dimer is elevated does not necessarily mean the patient will have a significant clot. Many factors can contribute to an elevated d-dimer: recent surgery , pregnancy, inflammation and trauma to name a few. If neg, there is a very high probability no clot is present. ...Read more

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What do d-dimer test results of 0.12ug/mL mean?

D-dimer: The value shows it is highly unlikely that you have a DVT. A value of more than 0.50 gives a bigger risk of a bloodclot, but still needs to be comfirmed by a scan ...Read more

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Other than a clot, what else could cause an elevated d-dimer test? Mine was approx 270... I was told cut off was 230

Clinical context: D-dimer values near the edge of a reference range are difficult to interpret, and are meaningful only in the context of the big picture. There are false-positives. If a search for a thrombus / thromboembolus and for disseminated intravascular coagulation were non-revealing, perhaps you would do best simply to be thankful for good health. ...Read more

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My NEICE d dimer test came back high 2.3 high. She has a crohn disease. Does she need to see any specialist and who ?

Nonspecific: A d-dimer is a nonspecific blood test that can be indicative of many things. Sometimes it can be a clue pointing towards active inflammatory bowel disease. Inactive chrons disease can be managed by a general practitioner but if symptomatic disease is best managed by a gastroenterologist. ...Read more

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If you are on combined oral pill, will that make a 'd dimer' test positive like pregnancy does when you have a d dimer test done?

Usually not: Even though average D-dimer levels are higher in women on contraceptive pill, the results are still within normal levels. You may consult this site for more info: http://archderm.jamanetwork.com/article.aspx?articleid=711883 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Can a D Dimer test rule out a blood clot?

Can a D Dimer test rule out a blood clot?

Can be suggestive: the blood test is useful to suggest thrombosis in the appropriate clinical context but needs to be confirmed with Doppler scanning or angiography ...Read more

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Which is more effective for a diagnosis of a clot ? D-dimer test, or ultrasound ?

It depends....: Both are used in the workup of a blood clot. A d-dimer is used for patients at low clinical risk for a clot. For those who have a positive d-dimer or who are at medium or high risk, an ultrasound is needed to further evaluate for a clot. If you are concerned about a blood clot, i would seek immediate medical attention. ...Read more

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Could four d-dimer test over the course of 3 weeks be wrong. \u0026#40;they're coming back normal\u0026#41; still have leg pain though. Very worried.

Could four d-dimer test over the course of 3 weeks be wrong. \u0026#40;they're coming back normal\u0026#41; still have leg pain though. Very worried.

It depends,,,: It depends on the kind of leg pain and why these tests were done. If your leg pain comes from walking and being on your feet and it's warm or hot to touch you should see a doctor fast and possibly go to the hospital for a blood clot issue, but if it's nonspecific, then it's likely not urgent. You're on pain meds so it might be a neurological issue. So see your dr. Soon to be sure. Good luck. ...Read more

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I just had a d dimer test done I am only 41 and this is the result is D-DIMER 0.50 mg/L FEU <0.50 mg/L FEU does that mean I could have a blood clot ?

Why DDimer?: I need to know the reason you were ordered for D dimer. Your number is very low and should be considered negative unless you have signs and symptoms of clotting in your legs or lungs, then I would get further testing ...Read more

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I have inner thigh pain.. And i showed up negative on a d dimer test. What could be the problem?

I have inner thigh pain.. And i showed up negative on a d dimer test. What could be the problem?

Several things: These are symtoms that need to be evaluated thoroughly your physician. He/she will be able to discuss his/her findings and suggest a plan. ...Read more

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How useful is a d-dimer test in ruling out a blood clot in the lower leg?

How useful is a d-dimer test in ruling out a  blood clot in the lower leg?

Useful: A negative result of D-Dimer has a 97%+ predictive value in ruling out deep vein thrombosis. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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D Dimer test 550, high red blood count, long term shortness of breath for 5 years. What could be problem?

D Dimer test 550, high red blood count, long term shortness of breath for 5 years.  What could be problem?

Context: Is the d dimer normal or high for the lab? Is there a history of smoking cigarettes, or a history of blood clots or emphysema? Chest pain, coughing up blood? This sounds like lung problems, but could also indicate a blood problem. More clinical info is needed. ...Read more

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Can the d-dimer test be accurate enough to diagnose a pulmonary embolism?

Can the d-dimer test be accurate enough to diagnose a pulmonary embolism?

Used for ruling out : The d-dimer test is most helpful in ruling out pulmonary embolism. If it is negative, the chance of having a pe is quite small. If it is positive, then a further confirmatory test is still necessary to make the diagnosis of pe. ...Read more

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7.5 weeks post partum and c section. Would a d dimer test come out normally or would itstill be elevated from pregnancy and surgery?

Several causes: It is possible that the D-Dimer is be normal, and it is possible that it is still elevated due to ongoing tissue healing since surgery. The D-Dimer is typically done to evaluate for a possible blood clot. However, it is commonly falsely high due to other reasons such as an underlying infection, inflammation such as arthritis, kidney problems, and heart problems. ...Read more

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What to do if I had a positive d-dimer test but the doctor did not send me for a CT scan?

What to do if I had a positive d-dimer test but the doctor did not send me for a CT scan?

Short of breath?: D-dimer is not specific for a pulmonary embolus (PE). Many things can elevate it. If you do not have chest pain, are not short of breath and can walk/run/execise normally, you don't have any reason for a CT scan. Why was test done? CT for PE involves radiation and exposure to IV contrast which can injure the kidneys. With no symptoms, all you get is risk-no benefit. ...Read more

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Could an ultrasound scan miss a DVT as iam at high risk of a DVT and is 422 high for a d dimer test?

Could an ultrasound scan miss a DVT as iam at high risk of a DVT and is 422 high for a d dimer test?

Ultrasound for DVT: Ultrasound for lower extremity DVT's have great sensitivity and specificity meaning they are very good at picking up a DVT. There is a 2% chance of somebody having a negative scan and having one found 1 week later according to studies, although repeating it is often done if there is strong suspicion. D-dimer values are not universal so that may be high but values can be high in a lot of disease. ...Read more

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Had treponin tests negative , normal EKG and d dimer test . Normal echo but still have chest pains. Is it heart related ? Is this all chosto?

Relax: You've had almost every test possible short of a heart catheterization to rule out a heart problem. I don't know the cause of your chest pains but at your age costochondritis, a musculoskeletal issue or anxiety, is much more likely. ...Read more

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I had a D dimer test done that came back at .84 and then another one at .92 a week later. I had a leg ultrasound that came back negative for clots. Should I do any follow up testing? I still have on and off leg pain but no shortness of breath. Could t

Ruled out: A positive d-dimer never rules in a clot. The ONLY value a d-dimer has is that when it's negative, it rules a clot out. Your negative ultrasound ruled out a clot with high accuracy. D-dimer is just a screening test. US is definitive. You don't have a clot. Your pain is due to something else. Have that issue evaluated. Good luck to you! ...Read more

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My doc told me i had arthritis in my left leg. I have been having like 3 second hot flashes in my ankle.I had a negative d-dimer test.What could it be?

My doc told me i had arthritis in my left leg. I have been having like 3 second hot flashes in my ankle.I had a negative d-dimer test.What could it be?

Possible nerve: Irritation. Sometimes if a nerve is getting mildly irritated in a certain area, such as the peroneal nerve around the fibular head, you can have some heat like feeling transiently. Have you noticed any change in the way you walk prior to the burning? Any unusual pressure around areas prior to the burning? Where is the arthritis? If it is in the ankle, the inflammation can irritate small nerves too. ...Read more

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Calf pain and swelling for 3 weeks (1cm to 3cm bigger) known blood clotting problem but d-dimer test ok, still possible dvt or something else?

Calf pain and swelling for 3 weeks (1cm to 3cm bigger) known blood clotting problem but d-dimer test ok, still possible dvt or something else?

Calf Swelling: Previous deep vein thrombosis puts you at high risk for recurrence. New leg swelling and pain should prompt an ultrasound. Although it is true that a negative d-dimer is a good test to rule out venous thromboembolic disease in low risk patients, no test is perfect. If you are a high risk patient, particularly is swelling is progressing up your leg an ultrasound is recommended. ...Read more

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What does a long-tail in a d-dimer test mean? Has high-cholesterol and family history of high b.P./strokes. Had chest pain and shortness of breath

What does a long-tail in a d-dimer test mean? Has high-cholesterol and family history of high b.P./strokes. Had chest pain and shortness of breath

Complicated question: D-dimer is a fibrin degradation product a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two cross linked d fragments of the fibrinogen protein .It is use to checked blood clots.The other part when you have all these factors, you have tendency for stroke. ...Read more

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Diagnosed with bakers cyst after 8 months of painful swollen left leg. d dimer test was negative for dvt. still anxious about having a dvt. can a bakers cyst cause bad symptoms? should I not worry about dvt? I'm a 21 yr old female

Diagnosed with bakers cyst after 8 months of painful swollen left leg. d dimer test was negative for dvt. still anxious about having a dvt. can a bakers cyst cause bad symptoms? should I not worry about dvt? I'm a 21 yr old female

Bakers cyst: A bakers cyst could cause a DVT in people who are predisposed to have coagulation problems.
You should not be worried about a DVT if there are not risk factors for it. For example, taking birth control pills predisposes patients to have coagulation problems.
A DVT usually causes symptoms like pain and edema. ...Read more

Dr. Liawaty Ho
3 doctors shared insights

Herring Antibody Test (Definition)

Testing for ige antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms. Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens ...Read more


D Dimer (Definition)

D-diner is a breakdown product from blood clots. It can be found elevated in certain conditions like pulmonary embolus (blood clot which travels to the lung) deep venous thrombosis (blood clot in deep vein of legs usually) and disseminated intravascular coagulation (diffuse clot formation from severe infection which ...Read more