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Doctor insights on: D Dimer

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Dr. Lester Thompson
Board Certified, Pathology
28 years in practice
1M people helped
1

1
What is a ?D-dimer test?

Dr. Lester Thompson
Board Certified, Pathology
28 years in practice
1M people helped
What is a ?D-dimer test?

Thrombosis: The d-dimer is a fibrin degradation product (or fdp) which represents a small protein fragment in blood after a blood clot is broken down. The value can be used to test for clotting or thrombosis problems. However, a single value or a value in isolation should not be used. ...Read more

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Dr. William Forsythe
Board Certified
22 years in practice
170K people helped
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Dr. William Forsythe
Board Certified
22 years in practice
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Dr. Ted King
Board Certified, Phlebology
35 years in practice
4M people helped
2

2
What could cause abnormal d dimer result?

Dr. Ted King
Board Certified, Phlebology
35 years in practice
4M people helped
What could cause abnormal d dimer result?

High d-dimer: High d-dimer results can occur because of essentially inflammatory process. Besides blood clots, high results can be due to various causes: liver disease, high rheumatoid factor, inflammation, malignancy, trauma, pregnancy, recent surgery, and advanced age, to name a few. A high d-dimner is very non-specific. A low d-dimer is very help[ful in ruling out blood clots. ...Read more

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Dr. William Forsythe
Board Certified
22 years in practice
170K people helped
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Dr. William Forsythe
Board Certified
22 years in practice
170K people helped
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Dr. Robert Binford
Board Certified, Thoracic Surgery
33 years in practice
1M people helped
3

3
What is the definition or description of: d dimer?

Dr. Robert Binford
Board Certified, Thoracic Surgery
33 years in practice
1M people helped
What is the definition or description of: d dimer?

Marker for clot: D-diner is a breakdown product from blood clots. It can be found elevated in certain conditions like pulmonary embolus (blood clot which travels to the lung) deep venous thrombosis (blood clot in deep vein of legs usually) and disseminated intravascular coagulation (diffuse clot formation from severe infection which actually leads to bleeding). ...Read more

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Dr. James Stone
Board Certified, Interventional Radiology
12 years in practice
92K people helped
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4
Can you tell me in january, they done just a CT scan on my lungs and showed nothing and sent me home. I had accurate is the d-dimer for clots?

Dr. James Stone
Board Certified, Interventional Radiology
12 years in practice
92K people helped
Can you tell me in january, they done just a CT scan on my lungs and showed nothing and sent me home. I had accurate is the d-dimer for clots?

Not accurate : A negative d dimer is helpful for ruling out pulmonary clots. A positive d dimer is basically useless as it can occur from a variety of reasons. A CT angiogram is close to the gold standard for determining whether there are clots in lungs. Regardless of what the d dimer showed, if the CT was negative and they used contrast for the CT then you are in the clear. ...Read more

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Dr. William Forsythe
Board Certified
22 years in practice
170K people helped
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Dr. John Fung
Board Certified, General Surgery
34 years in practice
1M people helped
5

5
Purpose of a d-dimer test?

Dr. John Fung
Board Certified, General Surgery
34 years in practice
1M people helped
Purpose of a d-dimer test?

Clotting disorders: D-dimer is a small protein fragment present in the blood after a blood clot is broken down by the naturally occurring process of clot breakdown, called fibrinolysis. D-dimer levels are determined by blood tests and elevations can be seen in conditions of blood clots, such as with deep vein thrombosis, with severe infections and with advanced liver disease (which normally clears d-dimer). ...Read more

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Dr. Carlo Hatem
Board Certified, Pulmonary Critical Care
20 years in practice
4M people helped
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Dr. Nestor Del rosario
Board Certified, Addiction Medicine
29 years in practice
1M people helped
7

7
I have had 2 normal d dimer tests in the past 2 weeks. Is it safe to assume i don't have a blood clot, even if my leg is sore?

Dr. Nestor Del rosario
Board Certified, Addiction Medicine
29 years in practice
1M people helped
I have had 2 normal d dimer tests in the past 2 weeks. Is it safe to assume i don't have a blood clot, even if my leg is sore?

Look at risk: You have to ask the reason why the d dimer is being done. In all likelihood, there is no blood clot as the work up is negative. Like a previous question, the risk and presentation has to be evaluated first and then a study is done to work it up. I don't know why the test was done, but in all likelihood the importance of a negative test is more to point negative but positive test is more a problem. ...Read more

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Dr. Lester Thompson
Board Certified, Pathology
28 years in practice
1M people helped
8

8
Can having an elevated d dimer be dangerous?

Dr. Lester Thompson
Board Certified, Pathology
28 years in practice
1M people helped
Can having an elevated d dimer be dangerous?

Perhaps: The d-dimer is a fibrin degradation product (or fdp) which represents a small protein fragment in blood after a blood clot is broken down. The value can be used to test for clotting or thrombosis problems. However, a single value or a value in isolation should not be used. Elevations may suggest a clotting problem. ...Read more

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Dr. George Ciechanowski
Board Certified, Pulmonary Critical Care
35 years in practice
115K people helped
9

9
Chest pain. Ekg, d-dimer, asa, chest xray, ESR "normal". Echo says "restrictive pattern lv diastolic fill". Anxious re risk of cad/athero & heart attack. ?

Dr. George Ciechanowski
Board Certified, Pulmonary Critical Care
35 years in practice
115K people helped
Chest pain. Ekg, d-dimer, asa, chest xray, ESR "normal". Echo says "restrictive pattern lv diastolic fill". Anxious re risk of cad/athero & heart attack. ?

More work up needed: Stress testing and ultimately cardiac cath. To rule out CAD as a cause. ...Read more

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Dr. Kenneth Bennet
Board Certified, Nuclear Medicine
13 years in practice
17K people helped
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Dr. William Forsythe
Board Certified, Emergency Medicine
22 years in practice
170K people helped
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