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Doctor insights on: Cystic Fibrosis Cf Pancreatic Diseases

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Dr. Corey Clay
3 Doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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For what reasons might the pancreas get blocked by mucus in cystic fibrosis patients?

For what reasons might the pancreas get blocked by mucus in cystic fibrosis patients?

Thick: The secretions in cystic fibrosis are more viscous (thicker) than normal and interfere with normal drainage resulting in blockages of the bronchial tubes of the lung with resultant pneumonia and lung injury. Similar issues involve the pancreas. Newborns with the disease frequently have difficulty passing their bowel movements. ...Read more

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Can you get a pancreas transplant in cystic fibrosis?

Can you get a pancreas transplant in cystic fibrosis?

Yes: Yes you can. Some patients can get a lung pancreas or a liver, pancreas. They have done very well at our institution. ...Read more

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Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown

Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown

Maybe: Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information. ...Read more

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My son has hirschsprung disease. My wife tested neg. For cystic fibrosis. Are the two related? Should I be tested for CF? I'm 32 w/no issues.

No, not related: Hirschsprung's disease is a congenital condition that leads to absence or lower numbers of nerve cells in the large intestine that are responsible for allowing the colon muscles to function, leading to constipation or inability to pass stool. Cystic fibrosis is an inherited recessive disorder of salt transport leading to thickened secretions. If your wife is negative, no need for you to be tested ...Read more

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My son & wife tested neg for Cystic Fibrosis through screening test, not sweat test. However my son has hirschsprung disease. Should I test for CF - or it's high unlikely I have it? I'm 32. Feel fine

I wouldn't: There is no relationship between Hirschprung disease and CF. If you wand to know if you are an asymptomatic carrier of CF, the tests are available. However, you don't get to age 30 without symptoms when you have the disease and your fertility would also be diminished. If your wife is not a carrier, you can not produce babies with CF. ...Read more

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Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

Not true: Cystic fibrosis is a metabolic disorder more common in caucasions by present in many populations. The incidence is 1/3500 caucasion, 1/17, 000 african american, 1/80, 000 native american. It arises in mutations in the cftr gene that regulates cellular transport of chloride.There are in excess of 700 known mutations recorded but most common is the delta 508. ...Read more

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What does it mean to have cystic fibrosis? Is this a noncurable disease?

What does it mean to have cystic fibrosis? Is this a noncurable disease?

Lung disease, & yes.: Cystic fibrosis is a genetic disease that causes thick secretions in the lungs and many other organs in the body. It is most often diagnosed in childhood. Children with this disease often have recurrent lung infections, as well as complications such as diabetes, intestinal obstruction, and liver disease. It is not curable, but the latest treatments allow patients to live into their forties. ...Read more

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Cystic fibrosis is a disorder of genes but which ones?

Cystic fibrosis is a disorder of genes but which ones?

CF gene mutations: There are currently more than 1900 mutations that are known to cause cf. About 70% of CF pts in us have deltaf508 mutation, as 1 in every 25 persons is a carrier for this mutation. All these mutations result in abnormal activity of a protein called cftr which causes all the CF related problems. Genetic testing can give the specific mutation each pt has. Talk to your local CF center. ...Read more

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Can someone have addison's disease and cystic fibrosis?

Can someone have addison's disease and cystic fibrosis?

Yes, they CAN, but: Addison's disease has been associated with other autoimmune glandular disorders, including malabsorption and type I diabetes. But cf, although having pancreatic (including diabetes i) & GI deficiencies (malabsorption), is a chromosomal not autoimmune disorder. Their association would be purely coincidental. See: neufeld, m, et al. Medicine: september 1981 - volume 60 - issue 5 - ppg 355-362. ...Read more

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What is a disease similar to diabetes or cystic fibrosis?

What is a disease similar to diabetes or cystic fibrosis?

Pancreas: The two diseases you mention involve damage to the pancreas, but are otherwise fundamentally different. ...Read more

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In regards to cystic fibrosis, can kefir help the disease?

Possibly...: There are some studies to suggest that probiotics can have a positive effect on the immune system and may help CF patients fend off infections. Your CF doctor should be able to give you more info. See http://cfcenter. Stanford. Edu/services/nutrition.Html. ...Read more

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Do both parents have to be cystic fibrosis carriers in order for their child to be born with this disease?

Yes: Both parents have to be carriers and then their child has 25% chance of having the disease, 50% chance of being a carrier and 25% of not even being a carrier. The most common mutation causing cystic fibrosis is? F508. But there are over 1500 mutations identified so far. ...Read more

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Is their there significant risk of cancer or disease with asymptomatic Cystic Fibrosis Carrier? Should one be worried?

Is their there significant risk of cancer or disease with asymptomatic Cystic Fibrosis Carrier? Should one be worried?

No Risks For You: Cystic Fibrosis is a genetic disease causing secretions from mucus & sweat glands to thicken which interferes with function of many organs, mainly lungs, GI tract, & more. It is inherited as autosomal recessive pattern meaning a gene must be inherited from both parents. Having only 1 gene is the carrier state meaning you can pass along the gene but there are no risks related to CF for a carrier. ...Read more

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Art around what age do the obvious symptoms of cystic fibrosis set in? I'm worried of the disease although I played football for 5 years since 7th gra

CF worry: Hi KennethH, typically CF is diagnosed in infants and children. However, about 7% of cases can present in adulthood. These tend to be less of the typical disease and more likely to develop diabetes, GI symptoms, and even infertility. Adults are more likely to have normal pancreatic function, unusual genetic mutations and equivocal sweat chloride tests. If you are worried, talk to your doctor. ...Read more

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What kind of disease is cystic fibrosis?

What kind of disease is cystic fibrosis?

Genetic: It's a genetic disease that primarily effects the lungs. Here is a great site to learn about cystic fibrosis: http://www. Cff. Org/ ...Read more

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Will cystic fibrosis be confused with another disease?

Yes: Cystic fibrosis can be confused with other diseases of the lung or the GI tract. Appropriate testing does exist that can guide the proper diagnosis. ...Read more

Dr. William Walsh
988 Doctors shared insights

Cystic Fibrosis (Definition)

A genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients and average life expectancy of patients with cystic fibrosis ...Read more


Dr. Michael Shim
390 Doctors shared insights

Pancreatic Diseases (Definition)

32 M asks: What is the definition or description of: Pancreatic diseases? ANS: this is a good google question. I am ...Read more