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Doctor insights on: Cystic Fibrosis Cf Occupational Therapists

Yes: Cystic fibrosis is a common indication for lung transplant. ...Read more

Trials: Clinical trials for genetic therapy are underway. As of this time there is no approved method for gene tx in cf. Kalydeco, (ivacaftor) a new drug, dose reverse the effects of one subtype of cf, but it dose so by aiding the damaged sodium-chloride transporter to get in proper position and function normally. ...Read more

Yes: Because of pancreas damage as well, combined bilateral lung plus a pancreas transplant may be done. ...Read more

No: Two completely different diseases. CF is an inherited disorder leading to failure to clear mucus and repeated infections. It does end up with fibrosis in the lungs. Idiopathic fibrosis is a disease of unknown cause where scar tissue replaces normal lung and eventually causes respiratory failure. ...Read more

Some are: Some families have multiple members who develop pulmonary fibrosis although sporadic cases are more common. The exact genetic inheritance is unknown. ...Read more

So far not at all: Trying to replace the faulty gene has been a failure so far. The new science of epigenetics tells us that our genes (even "bad" ones) are changed by diet and life style. I havegiven children with CF vitamin supplements. They help greatly but there is no cure. Find a physician who uses nutrient treatment. ...Read more

Not available yet: Gene therapy is not available for cystic fibrosis (CF) yet (2012). Having said that, the underlying concept is that since CF is a genetic disease (meaning there is a defect in a gene), by repairing that defect through gene therapy, one can, hopefully, cure the disease. ...Read more

Significantly: CF is associated with repeated lung infections that result in absence from school and social activities. ...Read more

Yes: Lung transplantation is a very important treatment option for people with cystic fibrosis that is severely limiting their physical ability. If successful, and it usually is, lung transplantation can offer a person with cystic fibrosis a renewed chance to regain the ability and energy to do many activities that others without this condition take for granted, including some sports. ...Read more

Yes. Talk to OB.: Cystic fibrosis is an inherited genetic disorder. Prospective parents can be tested to see they are carriers and discuss with genetic counselor the chance of having child with CF if one/both are carriers. Post-conception testing is also available. Talk to your ob. Here's link for additional info: http://www.Acog.Org/~/media/for%20patients/faq171.Pdf?Dmc=1&ts=20120518t1505423920. ...Read more

Women can: Men are infertile, but woman can have children, at a serious risk to their health. ...Read more

Cystic fibrosis: involves large amounts of mucus in the airways. Therefore it is difficult for air to flow due to mucus obstructing airways. Pulmonary fibrosis involves diffuse scar tissue in the lung parenchyma, making it difficult to expand (Restrictive). ...Read more

Yes: Meconium is the normal fecal debris composing the accumulated intestinal contents at birth.It is heavily colored by bile, dark and sticky. Meconium ileus can occur when the meconium has abnormal glue like stickiness caused by CF and will not empty from the bowel.The blockage can require emergency surgery. ...Read more

Not available: There is currently no gene therapy available for cystic fibrosis (cf). Since CF is a genetic disease, there is hope that, one day, gene therapy may provide a cure for this disease by, essentially, correcting the underlying genetic defect. ...Read more

Yes: Improvement in quality of life after double lung transplant can be dramatic. Most patients come off of oxygen and have much better quality of life by 6 months after transplant. The improvement after lung transplant can last a long time (years). ...Read more

Yes: I'm afraid so.

Pulmonary fibrosis: While I have not seen it commonly there are some families with a history of pulmonary fibrosis. Most of my office patients and previous fibrosis patients I have come across are the only ones in their family with fibrosis. I have one patient in my practice with several family members with progressive and ultimately fatal fibrosis. She has been evaluated at duke university with a genetic workup. ...Read more

Recessive: Both parents must carry the gene with a 25% chance (1:4) with each conception that the baby will have cystic fibrosis. ...Read more

It should: Cystic fibrosis is a genetic condition causing significant lung dysfunction. A double lung transplantation replaces the native lungs with supposedly normal lungs, eliminating the problem, but replacing it with problems directly related to transplanted lungs, i.e. Chronic rejection or bronchiolitis obliterans. ...Read more

Correct gene defects: Cystic fibrosis is a genetic disorder where a dysfunctional cftr protein causes problems in various organ systems. By restoring the function of this protein in the involved body systems, it is hoped that normal functionality will be restored & the harmful effects of CF disease will improve. There are still several obstacles before it can be successfully implemented in CF patients everywhere. ...Read more