Doctor insights on:
Cystic Fibrosis And The Pancreas
Cystic fibrosis is a genetic disorder involving lungs & digestive tract, causing recurrent lung infections due to thick inspissated mucus & poor growth in majority of patients due to malabsorption. Treatment involves inhaled respiratory therapies to prevent lung disease & pancreatic enzymes to enable absorption of nutrients. Average life expectancy is near 40 years, ...Read more
Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown
Maybe: Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information. ...Read more
Thick: The secretions in cystic fibrosis are more viscous (thicker) than normal and interfere with normal drainage resulting in blockages of the bronchial tubes of the lung with resultant pneumonia and lung injury. Similar issues involve the pancreas. Newborns with the disease frequently have difficulty passing their bowel movements. ...Read more
Progressive disease: Cystic fibrosis (CF) is a progressive, lifelong condition in which the glands that produce mucus, sweat, and intestinal secretions do not function properly. Thick mucus accumulates in the lungs, leading to breathing difficulty and infection. CF also impairs digestion, and affected males are usually infertile. ...Read moreSee 1 more doctor answer
Genetic disorder: It is a genetic disorder characterized by abnormal sodium channels, which affect a great deal of problems including the respiratory and digestive systems. It is most commonly diagnosed in infants failing to gain appropriate weight, and in children who have multiple chronic infections. ...Read moreSee 1 more doctor answer
Variable: This depends on the individual patient. There are several hundred CF mutations that have varying degrees of severity. The most common mutation, df508, can cause failure to thrive in infants, recurrent and very serious lung infections during childhood and often pancreatic insufficiency in children. While early diagnosis and preventive treatment have improved, CF is still a fatal disease. ...Read moreSee 1 more doctor answer
Organ Donation: Organ donation is possible and should be discussed with Lifelink. Many people do not realize that other useful tissues like heart valves, tendons, corneas are part of the donation process as well and can help recipients. In CF lungs heart, pancreas and liver are likely not able to be shared. See Lifelink http://www.lifelinkfound.org/index.cfm ...Read more
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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