Doctor insights on:
Cystic Fibrosis And Digestion
Absolutely: The thicker mucous secretions inherent to cystic fibrosis (CF) can cause a relative obstruction in clearing the airway tree of particulate matter/germs. Similarly, these secretions can obstruct the passage of pancreatic enzymes into the intestine leading to mal-digestion. ...Read moreSee 1 more doctor answer
Old Days: Back in the "old days, " patients with CF would frequently die, and the autopsy findings of the lungs showed scarring ("fibrosis") and bubbles ("cysts, " "cystic"). Thus, it was called cystic fibrosis. We know much more now about this disease, but the old name stuck. ...Read moreSee 1 more doctor answer
In a way: Most patients with diabetes have either a failure of the pancrease (pancrelipase) to produce Insulin or develop resistance to Insulin for various reasons. In cf, there is pancreatic insufficiency due to injury to the pancrease (pancrelipase) from the disease itself... And this can lead to CF related diabetes (where more Insulin is needed). ...Read moreSee 1 more doctor answer
Yes: Meconium is the normal fecal debris composing the accumulated intestinal contents at birth.It is heavily colored by bile, dark and sticky. Meconium ileus can occur when the meconium has abnormal glue like stickiness caused by CF and will not empty from the bowel.The blockage can require emergency surgery. ...Read more
Can benefit some: Lung transplantation is an option when the medical regimen can not prevent further decline in end stage lung disease. The timing of the transplantation is important in maximizing the benefit of the transplant. The average survival at one year is around 90%, five years is approx 55% depending on the center. I hope that this helps. Prmg pediatrics/respiratory fax 858 259 9689 for ?S. ...Read moreSee 1 more doctor answer
Deficient enzymes: Pancreas in everyone makes enzymes that body uses to break down food. In person with CF, pancreatic ducts get blocked. This makes it harder for these enzymes to enter the small intestines. Decreased pancreatic secretions limit breakdown of fats, which cannot be absorbed by the small intestine because they are too large. Small intestine unable to neutralize acidic contents delivered from stomach. ...Read more
Kind of...: Cystic fibrosis (CF) is a genetic disease. Patients with the disease are born with a defective gene that is part of the body's system for making mucus, sweat, and digestive fluids. Their mucus is therefore abnormally thick and causes blockages in the lungs, pancreas and other organs that damage them and make them prone to infections and other problems. ...Read more
Lung Function: The gene itself will not affect tuberculosis. However, if an individual receives 2 recessive genes of the cftr mutation from their parents, they will develop cystic fibrosis (cf). Because CF can lead to repeated bacterial lung infections (among other things), the lungs would already be in a weakened state if exposed to the causative agent of tuberculosis. This might lead to faster disease onset. ...Read moreSee 1 more doctor answer
When babies are born, are they screened for cystic fibrosis? Also, can a chest xray indicate cystic fibrosis in the lungs?
Depends: The specifics of newborn screening are defined on a state to state basis. Many states screen for CF, but this was not added to the screening in my state until about 10 years ago. The x-ray changes that may be seen in some older CF patients are not present in early childhood and not specific to the disease when they are seen. ...Read moreSee 1 more doctor answer
Yes, they CAN, but: Addison's disease has been associated with other autoimmune glandular disorders, including malabsorption and type i diabetes. But cf, although having pancreatic (including diabetes i) & GI deficiencies (malabsorption), is a chromosomal not autoimmune disorder. Their association would be purely coincidental. See: neufeld, m, et al. Medicine: september 1981 - volume 60 - issue 5 - ppg 355-362. ...Read more
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