Doctor insights on:
Cystic Fibrosis Age Of Onset
What would the synptoms of adult onset cystic fibrosis be? And would it be likely at my age. Even worth asking my doc about?
GI or pulmonary: Symptoms in the pulmonary system such as chronic infection or airway problems (bronchiectasis) or GI revolving around pancreatic disease (diabetes, malabsorption or pancreatitis). Adult forms are being described more and more. If you have problems in these areas, or have a family member with cf, check with your physician about a work up. Http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc2626352. ...Read more
No: You are born with cystic fibrosis, you don't "get" it later in life. It may not be diagnosed right away depending on the type and severity of symptoms. For example, a newborn with an intestinal blockage would be picked up quickly, but an older child or even an adult who presented with mostly sinus symptoms might not get diagnosed until later. ...Read more
Varies: Unfortunately, there is no correct answer to this. It really varies and depends on various factors, including the type of mutation a patient may have. Symptoms may start soon after birth, or years later. ...Read more
Unlikely: At age 49, a diagnosis of cystic fibrosis would be very unlikely. That being said, a diagnosis of pulmonary fibrosis, which is different from cf, could be possible, and generally occurs later in life. Pulmonary fibrosis can give the same signs and symptoms as cf. You can experience shortness of breath, cough, fatigue, and weight loss. Smoking is a risk factor. ...Read more
Were all babies from 1997-present screened for Cystic fibrosis in the state of Texas? Also, at what age do the symptoms for cystic fibrosis set in?
No: If memory serves me well. CF was not added to the newborn screening program until later. About 10 years back, the state expanded its screening program from 5 to more than 25 conditions, including CF. The symptoms might present with bowel blockage at birth, obnoxious smelly stools in infancy or may not have obvious symptoms for years. There is some individual variation from case to case. ...Read more
Art around what age do the obvious symptoms of cystic fibrosis set in? I'm worried of the disease although I played football for 5 years since 7th gra
CF worry: Hi KennethH, typically CF is diagnosed in infants and children. However, about 7% of cases can present in adulthood. These tend to be less of the typical disease and more likely to develop diabetes, GI symptoms, and even infertility. Adults are more likely to have normal pancreatic function, unusual genetic mutations and equivocal sweat chloride tests. If you are worried, talk to your doctor. ...Read more
I was born with cystic fibrosis. I'm now 35 and my lung function has gradually worsened the last years. I know that survival age is about 40 and I'm at peace with that. However, I still wonder: are there any recent findings about cystic fibrosis?
Mgt: I would advise following your lung function closely with your pulmonary specialist, optimizing your nutrition, and treating any exacerbations with antibiotics and chest physiotherapy. The use of DNAase has been shown to be effective. Some patients may benefit from treatments specifically targeted to their genotype. The CF foundation is another good resource for patients. Stay well. ...Read more
Yes: I would use a term "mild" or "atypical" form of cystic fibrosis. Cystic fibrosis is caused by mutation involving cftr gene, and there are a few hundred different mutations. Atypical or mild form of CF manifest at a later age than in infancy as often seen in classic form, and mild in symptoms. ...Read more
Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US. A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications. Emotional & phys. Development depend on severity, time in hospital, complications. Morb. & mort. Factors afect emotional, cognitive behavior. ...Read more
As a carrier:
Genetic carrier testing:
more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more
I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?
What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?
Acording to the CF foundation: the overall birth prevalence is 1/3700. It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000.
More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more
Genetic disorder: It is a genetic disorder characterized by abnormal sodium channels, which affect a great deal of problems including the respiratory and digestive systems. It is most commonly diagnosed in infants failing to gain appropriate weight, and in children who have multiple chronic infections. ...Read more
Inherited disease: Cystic fibrosis (CF) is an inherited disease that affects the cells lining the lungs, sinuses, intestines, spleen and liver. It prevents chloride ions from crossing the cell membranes properly. This can clog organ ducts. In the lungs, the extra mucus crushes the cilia and leads to more lung infections. Medications can help; in late-stage disease, lung transplantation may be life-saving. ...Read more
Depends on genes: The risk of acquiring cystic fibrosis (CF) depends on whether the parents of a child are carriers for the gene. It is estimated that about 1 in 20 americans are carriers of the CF gene. In order for a child to acquire the disease, both parents must be carriers. If both parents are carriers, there is then a 25% chance that the child will acquire the disease. ...Read more
Cystic fibrosis: CF is a genetic disease that from birth causes the body to produce a thick and sticky mucus. This mucus interferes with the ability to breath and digest food. It is life threatening, but with good management people can live into their 40s and beyond with it. ...Read more