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Doctor insights on: Cymbalta Versus Effexor

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Dr. Alan Ali
Board Certified, Psychiatry
27 years in practice
177M people helped
1

1
When changing from cymbalta to Effexor do I need to ween my self off of one to the other. Or can I just switch?What is difference between the two?

Dr. Alan Ali
Board Certified, Psychiatry
27 years in practice
177M people helped
When changing from cymbalta to Effexor do I need to ween my self off of one to the other. Or can I just switch?What is difference between the two?

Cymbalta: Weaning is advised, with the help & guidance from your prescribing doctor. ...Read more

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Krishna Kumar
496 doctors shared insights

Venlafaxine (Definition)

Venlafaxine is a non-tricyclic which is a kind of serotonin-norepinephrine reuptake inhibiting drug (atypical anti-psychotic ...Read more


Dr. Alfred Forrester
Board Certified, Psychiatry
37 years in practice
149K people helped
2

2
How are cymbalta and Effexor XR different?

Dr. Alfred Forrester
Board Certified, Psychiatry
37 years in practice
149K people helped

Different compounds: Cymbalta and Effexor xr are different chemical compounds which are both used to treat depression and anxiety disorders; however, they share a similar "mechanism of action", in that both are serotonin and norepinephrine reuptake inhibitors (snri's). Cymbalta is also used in the management of fibromyalgia and (in europe, at least) urinary incontinence. Their side-effect profiles are also different. ...Read more

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Jonathan Jassey
Board Certified, Pediatrics
12 years in practice
825K people helped
3

3
My son 18 years old his in Effexor XL not doing well can he take Cymbalta its ok for his age?

Dr. Jonathan Jassey
Board Certified, Pediatrics
12 years in practice
825K people helped
My son 18 years old his in Effexor XL not doing well can he take Cymbalta its ok for his age?

Depression/anxiety: Yes that's fine for his age, let his doctor tell you how to start it and get off the effexor. ...Read more

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Dr. Chris Hawley
Board Certified, Family Medicine
19 years in practice
269K people helped
4

4
I've been taking cymbalta 120mg/day for years. It's now very expensive. Is generic Effexor an alternative especially for the chronic shoulder pain?

Dr. Chris Hawley
Board Certified, Family Medicine
19 years in practice
269K people helped
I've been taking cymbalta 120mg/day for years.  It's now very expensive.  Is generic Effexor an alternative especially for the chronic shoulder pain?

Effexor: Yes Effexor shares many of the same properties as Cymbalta and is much cheaper. Discuss with your doctor who will likely be willing to try it. You have to slowly go up icon the dosing, so don't give up too early if not helping on the starter dose. Your doctor can help you set up a dosing sequence tailor made for you. ...Read more

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Ravi Chand
Board Certified, Psychiatry
21 years in practice
3M people helped
5

5
Is it safe to be taking cymbalta, Effexor and Valium together?

Dr. Ravi Chand
Board Certified, Psychiatry
21 years in practice
3M people helped
Is it safe to be taking cymbalta, Effexor and Valium together?

Multiple Psych MEds: Unless there is a strong reason to, Effexor and Cymbalta work by the same mechanism, your risk for blood pressure will increase a lot valium is like xanax but much longer acting to calm anxiety, help with sleep and panic etc. ...Read more

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Dr. Heidi Fowler
Board Certified, Psychiatry
20 years in practice
532M people helped
6

6
I have never been able to achieve an orgasm, i was on Effexor and now am on cymbalta, they are used to treat my fibromyalgia please help me!

Dr. Heidi Fowler
Board Certified, Psychiatry
20 years in practice
532M people helped
I have never been able to achieve an orgasm, i was on Effexor and now am on cymbalta, they are used to treat my fibromyalgia please help me!

If you were unable: To achieve orgasm prior to use of Cymbalta or Effexor - than this goes beyond medication side effect. However, sexual experience can be negatively impacted by depression, fatigue and chronic pain. May wish to explore this issue further with your physician. ...Read more

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Dr. Rhonda Simons
Board Certified, Family Medicine
10 years in practice
758K people helped
7

7
Switching from Effexor to cymbalta reduced my drowsiness, after 2 month on cymbalta again i'm drowsy.Tapered dose from 60mg to 30mg last week.Regards?

Dr. Rhonda Simons
Board Certified, Family Medicine
10 years in practice
758K people helped
Switching from Effexor to cymbalta reduced my drowsiness, after 2 month on cymbalta again i'm drowsy.Tapered dose from 60mg to 30mg last week.Regards?

Check MTHFR: Genotype 677 ; 1298. Almost 100% of people treated for depression for extended periods of time are positive for these genes. It is related to low folate ; B12 levels which causes fatigue.Getting treated can help all your meds work much better because your body will finally be able to make its own serotonin, nor-epi, ; dopamine.Tx is safer than placebo-15mg of l-methylfolate, p5p 50mg, 4mg b12. ...Read more

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Dr. Lynne Weixel
Board Certified, Clinical Psychology
31 years in practice
9M people helped
8

8
Does Cymbalta cause weight gain. Also your thoughts on Effexor. Don't want to gain weight and am currently on Wellburin.tx?

Dr. Lynne Weixel
Board Certified, Clinical Psychology
31 years in practice
9M people helped
Does Cymbalta cause weight gain.  Also your thoughts on Effexor.  Don't want to gain weight and am currently on Wellburin.tx?

Be careful!: Even non-pregnant people need to be very cautious combining Wellbutrin with either of those medications - seizure risk is increased as well as other risks. All anti-depressant seem to result in weight gain for some folk - even ones that cause loss in others. In your case - definitely work w/ your OBGYN to be safe. Try to find a diet plan that will be good for you, your baby and weight control. ...Read more

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Dr. Colin Sanner
Board Certified, Neurology
15 years in practice
589K people helped
9

9
Effexor is known to raise blood pressure...Cymbalta not quite so ..Is this accurate?

Dr. Colin Sanner
Board Certified, Neurology
15 years in practice
589K people helped
Effexor is known to raise blood pressure...Cymbalta not quite so ..Is this accurate?

Correct: While all serotonin-norepinephrine reuptake inhibitors (snris) can raise blood pressure, generally those with more activity on norepinephrine levels (effexor, pristiq, savella) tend to have more effect on blood pressure than cymbalta, which has a 1:1 effect on norepinephrine and serotonin. ...Read more

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Dr. Nicole Carlberg
Board Certified, Psychiatry
14 years in practice
18K people helped
10

10
Effexor vs cymbalta, currently Effexor 225, suffering from somnolence, fatigue.Cymbalta in such case?Best regards for your care.

Dr. Nicole Carlberg
Board Certified, Psychiatry
14 years in practice
18K people helped
Effexor vs cymbalta, currently Effexor 225, suffering from somnolence, fatigue.Cymbalta in such case?Best regards for your care.

Psychopharmacology : There are many different small details taken into account when considering medication choices for patients. Effexor and Cymbalta have some similarities. From your brief description it appears as though an appnt is needed with your dr. Make a list of concerns, questions. Bring in your meds, talk about the changes you might want to consider to target your concerns. Schedule extra time if needed. ...Read more

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Effexor (Definition)

Venlafaxine is a non-tricyclic which is a kind of serotonin-norepinephrine reuptake inhibiting drug (atypical anti-psychotic ...Read more


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Dr. Umesh Patel
Board Certified,
37 years in practice
878K people helped
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