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Doctor insights on: Cymbalta Suggesting Abilify

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I am on cymbalta but it hasn't helped with my inertia, my doc is suggesting abilify, why is this different?

I am on cymbalta but it hasn't helped with my inertia, my doc is suggesting abilify, why is this different?

Mechanism of Action: Cymbalta is in a class of medications know as serotonin-norepinephrine-reuptake-inhibitors. Abilify is a partial Dopamine & serotonin agonist. I know that's a mouth full, but the bottom line is they affect brain chemicals differently. Everyone responds differently to different medications & it's very common, especially with antidepressants, to have vastly different responses to each medication. ...Read more

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Dr. Heidi Fowler
294 doctors shared insights

Abilify (Definition)

Abilify (aripiprazole) is an atypical antipsychotic with a unique mechanism of action. As with most atypical agents it is probably prescribed more often for mood disorders than psychotic disorders (like schizophrenia). It's associated with fewer movement side effects (eps) than the typical antipsychotics. It's unique mechanism of action is that it both stimulates ...Read more


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How safe is it to take cymbalta or abilify?

How safe is it to take cymbalta or abilify?

Safe with monitoring: Both medications are very safe if prescribed by doctors familiar with their use and with appropriate monitoring. The main serious adverse effects have to do with either the fact that the medicines may take a while to have beneficial effects (and during that early period when they have not helped, they can actually make things briefly worse) and preventable long term effects that require monitoring. ...Read more

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I have been on cymbalta and abilify for 3 weeks is it normal for me to still be very drowsy?

I have been on cymbalta and abilify for 3 weeks is it normal for me to still be very drowsy?

Drowsiness: The drowsiness seen with anti-depressants (Cymbalta) and major tranquillizers (Abilify) can persist for several months. You should consult your psychiatrist for dose adjustments in their two medications. ...Read more

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Does cymbalta really increase methadone, and Abilify increases the cymbalta? If so, is it wise to take these meds together?

Does cymbalta really increase methadone, and Abilify increases the cymbalta? If so, is it wise to take  these meds together?

Wow! Discuss w/ Dr!: That's a lot of medications and each one brings increased effects of the others with a particular concern in the combo of Cymbalta and buspirone for serotonin syndrome. Definitely discuss the wisdom w/ your provider but DO NOT stop any of these on your own. Do it under monitoring and consider adding a non-pharma psychotherapy strategy that might help you too. Best ...Read more

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Im on Cymbalta 60mg Risperdal 0.25mg can Abilify 1mg add to my medication because Risperdal Abilify both good for me?

Im on Cymbalta 60mg Risperdal 0.25mg can Abilify 1mg add to my medication because Risperdal Abilify both good for me?

That question is: A good one for your doctor. Those types of medication changes are best made in partnership with a physician who knows you, and your medication history, very well. It would be presumptuous of me to give you advice in this context, but your doc will be happy to discuss this with you at your next visit. Best wishes to you! ...Read more

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Abilify is work better with Cymbalta or zoloft?

It doesn't: work specifically better with one vs the other. Adding abilify to antidepressant can help for recalcitrant depression. ...Read more

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Can both Risperdal low dose 0.25 and Abilify 1mg combined with Cymbalta? ?

Can both Risperdal low dose 0.25 and Abilify 1mg combined with Cymbalta? ?

Yes: You might try all sorts of combinations under the watchful guidance of your psychiatrist. In your case the difficult decisions will have more to do with the Ativan (1 mg twice a day) as you might be experiencing problems with rebound anxiety and precipitation of depression. Don't make any medication changes without consulting with your doctor. ...Read more

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Why Abilify work good with cymbalta and not good with zoloft?

Why Abilify work good with cymbalta and not good with zoloft?

Response varies: Zoloft and Cymbalta work in different ways. This along with individual response may predict my outcomes are different with Abilify in combination with either zoloft or cymbalta. ...Read more

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What are the medical concerns for stopping 100mg Adderall habit? Abuse has lasted 6mos. Also on 60mg cymbalta, 5mg abilify, and 1 mg suboxone.

What are the medical concerns for stopping 100mg Adderall habit?  Abuse has lasted 6mos. Also on 60mg cymbalta, 5mg abilify, and 1 mg suboxone.

Few: For the most part, Adderall is out of your system quickly, each day it wears off and a person then takes it the next day. You may be tired for a couple of days after you stop the adderall. Otherwise, it should be okay. I hope you are seeing a physician, preferably an addictionologist or addiction psychiatrist to monitor you and help you with your problems. ...Read more

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Cymbalta (Definition)

Cymbalta (duloxetine) is an "antidepressant" medication. However, it is an approved treatment for a variety of indications to include (unipolar) depression, anxiety, and chronic pain (related to diabetic neuropathy, musculoskeletal and/or fibromyalgia). Pharmacologically, it primarily enhances 2 different neurotransmitters (serotonin and norepinephrine). It can cause a ...Read more