Doctor insights on:
Should I be worried about getting Parkinson's disease from 60 mg. of cymbalta? I read where it increases increases serotonin but decreases dopamine.
I am on cymbalta (duloxetine) for the rest if my life. Should I be worried about getting or tar dive dyskinesia or Parkinson's or motor control disorder?
My mom is 72 years old. Three years ago, she was diagnosed with dementia. She takes zoloft, cymbalta, (duloxetine) a cholesterol pill, nasonex, and aspirin. Does overmedication lead to parkinsonism symptoms?
Why do you wonder?: Check out these links: http://www.lifenph.com http://www.ninds.nih.gov/disorders/normal_pressure_hydrocephalus/normal_pressure_hydrocephalus.htm http://www.nlm.nih.gov/medlineplus/ency/article/000752.htm http://www.webmd.com/brain/normal-pressure-hydrocephalus ...Read moreSee 2 more doctor answers
Can you tell me in Parkinson's disease, does dopamine loss occur merely in the striatum or does it occur in the s.niagra too?
Pigmented nuclei: The dopamine loss involves predominantly the basal ganglia area, but also involves dorsal vagal nucleus, substantial nigra, and areas of any dopamine interaction within brain and brain stem. But, to be complete, Parkinson's is a multi-neurotransmitter degenerative deficiency syndrome with other neurotransmitter systems involved. ...Read more
Neuro is adding Lexapro 2 my meds, hope u can c my med list now! & on Cymbalta (duloxetine) but then quit Cymbalta (duloxetine) after 2wks. These 2 meds safe 2 take together?
Dose duration matter: Cross-tapering antidepressants is often done to prevent negative side effects from coming off a medicine. Even a medicine that isn't working well enough is often doing 'something' and patients may miss it when it's gone. Although Cymbalta (duloxetine) interacts with A LOT of drugs, Lexapro doesn't. Over a short period (2 weeks), at reasonable doses, there shouldn't be problem. ...Read more
In theory, it should: Theoretically, Azilect (rasagiline) (an MAO-B inhibitor) should help with many of the symptoms of Parkinson's for a certain period of time. However, as with all treatments for this disease, they are notoriously unpredictable. I've attached an article which I hope might help. Good luck! http://www.reprintsdesk.com/landing/hf.aspx?h=523154&hr=716110317&a=1&u=0&r=826399194 ...Read more
Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?
Not so simple: Most of the dopaminergic neurons end in the substantia nigra of the midbrain, originating in various deep brain structures. These nerves are already affected by the disease. Unaffected nerves of course still remain but remain connected to brainstem. So outside nerve cells (from another source like stem cells are needed) nerves don't like to be moved around anyway, because they often die. ...Read more
Dementia pugilistica: Numerous brain injuries cause disruptions in the fragile circuits that govern brain function. When injuries occur deep within the brain, they may affect a part of the brain that regulates movements. The part of the brain most involved in suppressing Parkinsons movements is called the substantia nigra. Mr. Ali has had injuries that damaged this part of the brain, which leads to his tremor. ...Read more
Many types: There are many types of drugs that are used to treat the symptoms of parksinson's disease. The mainstay of treatment are the dopaminergic medications include Levodopa (in various combinations) and the Dopamine agonists (e.g., rasagiline, ropinirole, etc). Other medications such as anticholinergics are to treat other manifestations of the disease. See: www.Parkinsons.Org & www.Michaeljfox.Org. ...Read moreSee 1 more doctor answer
Yes, Absolutely!!: Stay physically, mentally & spiritually (if important to you) active, to keep yourself in best physical condition & spirits. See a movement didorder specialist or at least a good local neurologist for Dopamine medication treatment, advice, education & inspiration to fight your pd! Azilect is a great med to start with, then possibly a 24 hour lasting Dopamine agonist like Requip XL or Neupro (rotigotine) :). ...Read moreSee 1 more doctor answer
Hopefully will help: Are you really 33, as you would be quite young for parkinson's. Sinemet (carbidopa and levodopa) is the main "go to" drug, and could very will be required in higher doses if your problem is progressing. Usually works quite well with limited adverse effects. Discuss fully with your neurologist. ...Read more