Doctor insights on:
Cymbalta Long Term Use
Benzodiazepines?: Maybe you meant to type "benzodiazepines" rather than "benzopines"? If so, the answer depends on which specific medication you mean. Different ones have different half-lives -- some quite long, and others much shorter. If you wonder about a specific medication, please ask again and we'll try to respond helpfully. ...Read more
Reduced acid: Usually long term use is not a problem- although suppressing acid for too long may lead to lack of complete digestion is some circumstances. Duodenal ulcers can be healed in 6-8 weeks of Omeprazole (or any other proton pump inhibitor or an h2 blocker). So unless there is chronic reflux, stopping therapy may be a good idea periodically. ...Read more
Very unlikely: First, it is unusual for Neurontin (gabapentin) to cause drug-drug interactions of any kind. Futhermore, the maximum useful dose is below 2400 mg daily, and higher amounts will not provide any enhanced effects. So, on it's own, the drug is certainly unlikely to cause seratonin syndrome ...Read more
Probably not: Liver dysfunction is not listed as a serious or less serious effect of Methadone use. One should always be careful with long term use of medications and have routine follow up and lab studies. Many medications used with Methadone certainly could cause liver dysfunction. Methadone is a very serious medication. Take its use and follow up very seriously. ...Read moreSee 1 more doctor answer
See doctor: There is a way to slowly withdraw from these drugs with minimal side effects. You need to review this with the prescribing doctor. ...Read more
More than 2 weeks: Most problems treated with otc should resolve quickly. ...Read more
Yes It Can: The natural production of hormones like testosterone is suppressed when someone is taking chemicals like morphine on a routinely resulting in hypogonadism which can weaken the bones. Also chronic opioid use can weaken the bones is by directly interfering with bone production. The cells that make bone, the osteoblasts, do not work very well when someone is using opioids routinely. ...Read more
Risks VS benefits: Saphris (asenapine) does not have more long term side effects than any other drug in its class that is atypical antipsychotics like risperdal, zyprexa or seroquel. Long term side effects include, hyperlipidemia, weight gain and diabetes. Tardive dyskinesia, a persistent movements which usually starts around mouth but occur in any muscle group should be monitored on regular basis by your pschiatrist. ...Read moreSee 1 more doctor answer
Long term side effects of short-term prednisone use? Took 60,60,40,40,20,20,10,10 mg for migraine. Expect any longterm effects?
COMMENTS: A good approach to break up a chronic daily headache pattern. Unlikely to experience any long-term consequences of 8 days of high dose steroids, but if you were to use over several weeks to months, risk rises for osteoporosis, anti-cholinergic effects, glaucoma, cataracts, avascular necrosis of shoulder, hip, or knee, etc. You are at extremely low risk. ...Read moreSee 2 more doctor answers
There are risks: The most common of which are weight gain and metabolic syndrome (diabetes with other metabolic changes). Also these carry a black box warning of increasing all cause mortality (but this really applies to the elderly) That being said it can be very effective in the right person and for the right condition. If you are taking it for pain then the risk/benefit may not warrant using this medication ...Read more
What are the pros and cons of the medication cymbalta (duloxetine) at 30mg? I have heard lots of bad long term side effects.
Cymbalta (duloxetine): It's approved for the treatment of depression, neuropathic pain, anxiety, and fibromyalgia. The most common side effects include nausea, dry mouth, headache, diarrhea, constipation, insomnia, dizziness, sleepiness, reduced appetite, sweating, abdominal pain, vomiting, and a decrease in sexual function. ...Read more
Does long term use of cymbalta (duloxetine) cause dementia. I mean 60 mg. for twenty or thirty years?
Are there any long term health consequences for taking Cymbalta (duloxetine) long term? I have been on it for 7+ years for depression. Currently 30 mg.
Not really.: You need a regular physical yearly and when you take any medications long-term, your doctor usually checks your metabolic profile, complete blood count, and general profile to rule out any illnesses and any unusual findings will be monitored. In addition, your dose is low and may just be a maintenance dose. You may want to discuss further with your doctor. ...Read moreSee 1 more doctor answer
- withdrawal from 90mg Cymbalta (duloxetine) - I'm reading a lot of scary long term effects of going off - is there possibility of awful side effects long term?
Could night sweats caused by Cymbalta (duloxetine) result in complications? I feel I can tolerate it, but wondering if night sweats do long term harm.
Not harmful : Night sweats can be an uncomfortable side effect of many medications. The night sweats are not a problem alone by themselves. However, night sweats can also occur with infections and systemic illness. See your doctor to make sure that you don't have another cause of your night sweats. Best wishes! ...Read more
I am on tramidol for arthritis in my spine, and cymbalta (duloxetine) for mood disorder, will these medications cause long term damage? Also I still have pain, why
No,i understand: Arthritis of your spine is a very common condition caused by a variety of causes, trauma, degeneration, other systemic condition--tramadol, Cymbalta (duloxetine) is one of the best arrangement we have for long term management--depending on your particulars like mri, source and quality of pain, other options available--ask your doc. ...Read more
Well......: The half-life of Cymbalta (duloxetine) is about 12 hours. It takes about 5 half-lives for medication to essentially be cleared from your system. However, since some people metabolize the medication more slowly it would be safe to assume the medication would be gone from your system within five days. ...Read more
Up to 6 weeks & more: A problem with antidepressants: there is no sure-fire way to pick one that will work for sure; and no sure fire way to get the correct dosage right off the bat. If you have taken Cymbalta (duloxetine) at a stable dosage for 6 weeks with no change in symptoms, you need either a changed dosage or another or a different medication; increasing dosage is usual next step before switching or adding medications. ...Read moreSee 1 more doctor answer
Return of symptoms!: I agree that you can experience serotonin discontinuation syndrome when stopping cymbalta, (duloxetine) which can feel like having the flu and sometimes strange sensations as well. As a result it should be tapered if possible with the help of your provider. This is pretty rare with Cymbalta (duloxetine) however; of greater concern is the possibility that your symptoms could recur, you should discuss this with your doc also. ...Read moreSee 1 more doctor answer
Just went from 20 mg of Cymbalta (duloxetine) to 40 mg. How long until a therapeutic level would be noticed?
About 6 Weeks.: Although the claim is made that some people may be able to start to feel less depressed within 2 weeks of taking one of these kinds of antidepressants, most people won’t start experiencing the full positive effects of the medication until 6 to 8 weeks after beginning it. It alters brain chemistry so it takes longer to get to those effects. ...Read more
I wasbumped up to 60 mg of cymbalta two weeks ago. How long before I feel better? Have been on it since 2006, went off twice. Should it still work?
I gained weight while taking cymbalta (duloxetine).How long will it take for medication to completely leave my system..So i can start losing the weight.
Cymbalta (duloxetine) weight gain: Cymbalta (duloxetine) can cause weight gain in several different ways. It can increase your appetite, reduce your sense of satiety when you eat, induce sedation you then attempt to manage by eating more, or improve a depression that caused you to initially lose weight. Your weight loss will depend on why you gained weight. For example, if it was from battling sedation, you can begin to lose weight immediately. ...Read more
Started cymbalta (duloxetine) and now i can't get orgasem. No matter how hard i try. Why? And how long will i need to take this to treat neuro symptoms?
Cymbalta (duloxetine) side effect: Per drugs.Com: -potential side effects include v'ed libido (6% of males), abnormal orgasm (4% of males), erectile dysfunction (up to 4%), delayed ejaculation (3%) ; ejaculatory dysfunction (3%). Don't know what your neurological condition is - can't predict duration of treatment you will need. ...Read more
I've been on cymbalta (duloxetine) for 3 weeks and it has done nothing for me, I know it can take longer but shouldn't I feel even a little improvement by now ?
Depends: U'r dose may need to be increased. Most people start on 30 or 60, then there docs ask them to go up to 60 or 120. May take up to 5-6 weeks. Recommend to call u'r doc to have a follow up after starting medications to discuss responses, potential dose adjustments or changes. ...Read more
My wife dropped cymbalta (duloxetine) dose from 60mg to 30MG 2 days ago. She was on 60 for 2 years. How long will it take to determine if the lower dose is right.
Im having headaches after starting cymbalta (duloxetine) on 60mg daily. How long should i wait before contacting Dr.
Call MD now: You're taking Cymbalta (duloxetine) 60 mg daily plus Prozac - dose unknown - with immediate headaches means probable side effect from Cymbalta (duloxetine) which can be interacting with Prozac causing too much serotonin in your system. Don't delay to see about lowering or stopping Cymbalta (duloxetine) dose. Additive effects from both meds if doses are too high could have serious consequences. ...Read moreSee 1 more doctor answer
How long for cymbalta (duloxetine) 30 mg to reach a steady state when going to 60..And how soon should you see a difference?
2-4 weeks.: With the right dose, you usually reach a steady state within 2 to 4 weeks. ...Read more