Top
20
Doctor insights on: Cymbalta Long Term Use

Share
1

1
What are the pros and cons of the medication cymbalta (duloxetine) at 30mg? I have heard lots of bad long term side effects.

What are the pros and cons of the medication cymbalta (duloxetine) at 30mg? I have heard lots of bad long term side effects.

Cymbalta (duloxetine): It's approved for the treatment of depression, neuropathic pain, anxiety, and fibromyalgia. The most common side effects include nausea, dry mouth, headache, diarrhea, constipation, insomnia, dizziness, sleepiness, reduced appetite, sweating, abdominal pain, vomiting, and a decrease in sexual function. ...Read more

3

3
Are there any long term health consequences for taking Cymbalta (duloxetine) long term? I have been on it for 7+ years for depression. Currently 30 mg.

Are there any long term health consequences for taking Cymbalta (duloxetine) long term? I have been on it for 7+ years for depression. Currently 30 mg.

Not really.: You need a regular physical yearly and when you take any medications long-term, your doctor usually checks your metabolic profile, complete blood count, and general profile to rule out any illnesses and any unusual findings will be monitored. In addition, your dose is low and may just be a maintenance dose. You may want to discuss further with your doctor. ...Read more

See 1 more doctor answer
5

5
Could night sweats caused by Cymbalta (duloxetine) result in complications? I feel I can tolerate it, but wondering if night sweats do long term harm.

Could night sweats caused by Cymbalta (duloxetine) result in complications? I feel I can tolerate it, but wondering if night sweats do long term harm.

Not harmful: Night sweats can be an uncomfortable side effect of many medications. The night sweats are not a problem alone by themselves. However, night sweats can also occur with infections and systemic illness. See your doctor to make sure that you don't have another cause of your night sweats. Best wishes! ...Read more

6

6
I am on tramidol for arthritis in my spine, and cymbalta (duloxetine) for mood disorder, will these medications cause long term damage? Also I still have pain, why

I am on tramidol for arthritis in my spine, and cymbalta (duloxetine) for mood disorder, will these medications cause long term damage? Also I still have pain, why

No, I understand: Arthritis of your spine is a very common condition caused by a variety of causes, trauma, degeneration, other systemic condition--tramadol, Cymbalta (duloxetine) is one of the best arrangement we have for long term management--depending on your particulars like mri, source and quality of pain, other options available--ask your doc. ...Read more

7

7
How long will cymbalta (duloxetine) stay in the body?

How long will cymbalta (duloxetine) stay in the body?

Well......: The half-life of Cymbalta (duloxetine) is about 12 hours. It takes about 5 half-lives for medication to essentially be cleared from your system. However, since some people metabolize the medication more slowly it would be safe to assume the medication would be gone from your system within five days. ...Read more

9

9
How long before I know this cymbalta (duloxetine) is working thoroughly?

Up to 6 weeks & more: A problem with antidepressants: there is no sure-fire way to pick one that will work for sure; and no sure fire way to get the correct dosage right off the bat. If you have taken Cymbalta (duloxetine) at a stable dosage for 6 weeks with no change in symptoms, you need either a changed dosage or another or a different medication; increasing dosage is usual next step before switching or adding medications. ...Read more

See 1 more doctor answer
10

10
What are the symptoms of quitting cymbalta (duloxetine) and how long should they last?

What are the symptoms of quitting cymbalta (duloxetine) and how long should they last?

Return of symptoms!: I agree that you can experience serotonin discontinuation syndrome when stopping cymbalta, (duloxetine) which can feel like having the flu and sometimes strange sensations as well. As a result it should be tapered if possible with the help of your provider. This is pretty rare with Cymbalta (duloxetine) however; of greater concern is the possibility that your symptoms could recur, you should discuss this with your doc also. ...Read more

See 1 more doctor answer
11

11
Just went from 20 mg of Cymbalta (duloxetine) to 40 mg. How long until a therapeutic level would be noticed?

Just went from 20 mg of Cymbalta (duloxetine) to 40 mg. How long until a therapeutic level would be noticed?

About 6 Weeks.: Although the claim is made that some people may be able to start to feel less depressed within 2 weeks of taking one of these kinds of antidepressants, most people won’t start experiencing the full positive effects of the medication until 6 to 8 weeks after beginning it. It alters brain chemistry so it takes longer to get to those effects. ...Read more

12

12
I gained weight while taking cymbalta (duloxetine).How long will it take for medication to completely leave my system. So I can start losing the weight.

I gained weight while taking cymbalta (duloxetine).How long will it take for medication to completely leave my system. So I can start losing the weight.

Cymbalta (duloxetine) weight gain: Cymbalta (duloxetine) can cause weight gain in several different ways. It can increase your appetite, reduce your sense of satiety when you eat, induce sedation you then attempt to manage by eating more, or improve a depression that caused you to initially lose weight. Your weight loss will depend on why you gained weight. For example, if it was from battling sedation, you can begin to lose weight immediately. ...Read more

13

13
Started cymbalta (duloxetine) and now I can't get orgasem. No matter how hard I try. Why? And how long will I need to take this to treat neuro symptoms?

Started cymbalta (duloxetine) and now I can't get orgasem. No matter how hard I try. Why? And how long will I need to take this to treat neuro symptoms?

Cymbalta (duloxetine) side effect: Per drugs. Com: -potential side effects include v'ed libido (6% of males), abnormal orgasm (4% of males), erectile dysfunction (up to 4%), delayed ejaculation (3%) ; ejaculatory dysfunction (3%). Don't know what your neurological condition is - can't predict duration of treatment you will need. ...Read more

14

14
I've been on cymbalta (duloxetine) for 3 weeks and it has done nothing for me, I know it can take longer but shouldn't I feel even a little improvement by now?

Depends: U'r dose may need to be increased. Most people start on 30 or 60, then there docs ask them to go up to 60 or 120. May take up to 5-6 weeks. Recommend to call u'r doc to have a follow up after starting medications to discuss responses, potential dose adjustments or changes. ...Read more

15

15
My wife dropped cymbalta (duloxetine) dose from 60mg to 30MG 2 days ago. She was on 60 for 2 years. How long will it take to determine if the lower dose is right.

My wife dropped cymbalta (duloxetine) dose from 60mg to 30MG 2 days ago. She was on 60 for 2 years. How long will it take to determine if the lower dose is right.

You should have: Some indication in 4-5 days. It depends on the reason for taking Cymbalta (duloxetine). (and the reason for cutting back on it).
Watch for changes in muscle tone, pain tolerance and mood and comportment. ...Read more

16

16
Will cymbalta (duloxetine) stay in my body long enough to taper itself?

Will cymbalta (duloxetine) stay in my body long enough to taper itself?

No: To get off the medication, it should be tapered
over several days due to its short half life.
It may take about two weeks. ...Read more

See 1 more doctor answer
17

17
How long does it take for the side effects of cymbalta (duloxetine) to end?

How long does it take for the side effects of cymbalta (duloxetine) to end?

Cymbalta (duloxetine): Depending on whether Cymbalta (duloxetine) is taken alone, how long, dose adjustment, how much, etc. Usually side effects of most antidepressants subside within 7 to 10 days, especially stomach upset. ...Read more

18

18
I'm having headaches after starting cymbalta (duloxetine) on 60mg daily. How long should I wait before contacting Dr.

I'm having headaches after starting cymbalta (duloxetine) on 60mg daily. How long should I wait before contacting Dr.

Call MD now: You're taking Cymbalta (duloxetine) 60 mg daily plus Prozac - dose unknown - with immediate headaches means probable side effect from Cymbalta (duloxetine) which can be interacting with Prozac causing too much serotonin in your system. Don't delay to see about lowering or stopping Cymbalta (duloxetine) dose. Additive effects from both meds if doses are too high could have serious consequences. ...Read more

See 1 more doctor answer