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Doctor insights on: Cymbalta

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What about cymbalta (duloxetine) discontinuation syndrome?

What about cymbalta (duloxetine) discontinuation syndrome?

Be very careful: Cymbalta, (duloxetine) like any ssri or snri, can create a physical dependency because of the effect they have on neurotransmitters. Everyone should be withdrawn from these drugs very carefully & cautiously. 3 weeks is the minimum one should take to reduce by each incriminate. Serious side effects, including suicide, have been reported when not properly. ...Read more

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Will cyclobenzaprine, Neurontin and cymbalta (duloxetine) alter the results of an emg test on lower extremities? And also, what exactly is that test used to determine?

Will cyclobenzaprine, Neurontin and cymbalta (duloxetine) alter the results of an emg test on lower extremities? And also, what exactly is that test used to determine?

No: An EMG nerve conduction study is used to evaluate nerve and muscle function and can detect nerve compression (pinched nerves) and nerve or muscle diseases. The results are not affected by your pain level, pain medications, muscle relaxants, or antidepressants. ...Read more

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Please describe the medication: cymbalta (duloxetine)?

Please describe the medication: cymbalta (duloxetine)?

Multiple uses: Cymbalta (duloxetine) is an "antidepressant" medication. However, it is an approved treatment for a variety of indications to include (unipolar) depression, anxiety, and chronic pain (related to diabetic neuropathy, musculoskeletal and/or fibromyalgia). Pharmacologically, it primarily enhances 2 different neurotransmitters (serotonin and norepinephrine). It can cause a variety of side effects. ...Read more

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Is it okay for my dentist to prescribe duloxetine/cymbalta for tooth pain?

Is it okay for my dentist to prescribe duloxetine/cymbalta for tooth pain?

Not recommended: Cymbalta (duloxetine) is a drug prescribed for neuropathic pain (e.g. diabetic neuropathy) or any other chronic pain. Dental pain is considered acute pain and common painkillers meds are NSAIDs, Tylenol (acetaminophen) and opioids. Maybe you have a peripheral neuropathy near your tooth that mimics toothache?
...Read more

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What is the description of a rash caused by cymbalta use? I have had a rash for 9 months on my hand. My doctor says it is from stress and there is nothing I can do except keep it dry. Since recent commercials state that cymbalta use can cause a rash, I

What is the description of a rash caused by cymbalta use? I have had a rash for 9 months on my hand. My doctor says it is from stress and there is nothing I can do except keep it dry. Since recent commercials state that cymbalta use can cause a rash, I

Hello.: Hello. I haven't seen the commercials that you are referring to. None of my patients have developed rashes on cymbalta (duloxetine). It is described that allergic reactions to Cymbalta (duloxetine) can present with both rash and hives. The hives can be all over the body, itch a great deal and sometimes may be more prominent in areas that are impacted by the sun.

The following skin changes have been reported when a person is coming off of cymbalta (duloxetine):
ecchymosis –purple discoloration of skin from a broken blood vessel.
Erythema –skin redness due to swelling of small blood vessels.
Erythematous rash – skin redness with possible itching, burning, tingling, pain and skin eruptions.
Exfoliative dermatitis – reddened skin with scaling and shedding of skin cells.
Hyperkeratosis – increased skin thickness
pruritic rash – extremely itchy, red, swollen bumps on the skin.
I hope that this is helpful. Maybe a doctor will answer who has actually seen a Cymbalta (duloxetine) rash. Take care. ...Read more

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My sister was prescribed Cymbalta (duloxetine). Is there a copay assistance for this medication? Thank you.

Maybe: Check out:
http://www. Pparx. Org/
http://www. Needymeds. Org/
http://www. Rxassist. Org/
Also talk to your pharmacist and physician to see what they may be able to tell you. ...Read more

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Can I use cymbalta (duloxetine) to treat my chronic phantom limb pain?

Can I use cymbalta (duloxetine) to treat my chronic phantom limb pain?

Phantom pain: Yes, you can. However, try to avoid any narcotics to control your phantom pain. Because the narcotics, such as lortab, morphine, tramadal etc, will decrease your endorphine production from your brain and spine by negative feeding back, which will make you sensative to the pain. Acupuncture is an appropriate way to control phantom pain by increase endorphine and and by balancing pain out. ...Read more

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Probably time to switch my cymbalta (duloxetine) 60mg to another OCD med...Has anyone used cymbalta (duloxetine) for OCD successfully--just curious--and yes I do cbt for ocd?

Probably time to switch my cymbalta (duloxetine) 60mg to another OCD med...Has anyone used cymbalta (duloxetine) for OCD successfully--just curious--and yes I do cbt for ocd?

Not in my practice.: It is not approved for ocd as you know, and there are scattered cases on the internet that show that it has helped a few. But mostly not helped others. I don't think it is a good choice for ocd and has no formal literature to back up its use. It is approved for gad, but not for ocd. Please discuss with your psychiatrist. I am shocked, you mean your cbt has not cured you? :) just kidding. ...Read more

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How effective is cymbalta (duloxetine)?

How effective is cymbalta (duloxetine)?

Fibromyalgia: Fair: This is one of three drugs with fda indication for fibromyalgia as well as a handful of others often used 'off label'
in this case it is started at a low dose and tapered up depending on side effects and effectiveness (i personally taper it up much more slowly than recommended to avoid dizziness and drowsiness). ...Read more

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What are some things you can to to sooth physical pain due to stress from computer work? Cymbalta> pt?

Counseling, group Rx: Doctors, like psychiatrists, can provide counseling on issues like this. They might also help with medication to ease the physical pain. Self-help groups, and supervised group therapy might also help. ...Read more

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Take cymbalta (duloxetine) 60 mg works well, doc prescribed 1mg clonezapam to help insomnia...Would like to taper off clonezapam what can I use? On fr 7 yrs

Take cymbalta (duloxetine) 60 mg works well, doc prescribed 1mg clonezapam to help insomnia...Would like to taper off clonezapam what can I use? On fr 7 yrs

Underlying cause: Unfortunately, meds can treat the symptoms but not the problem which may be leading to the symptom. Consider blood work, sleep diaries, caffeine intake, napping as potential diagnosis approaches. ...Read more

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Is 45mg/day of methadone and 60mg/day of cymbalta (duloxetine) safe to take together?

Is 45mg/day of methadone and 60mg/day of cymbalta (duloxetine) safe to take together?

Maybe: Can't answer for you specifically or for exact doses since that would involve doing an individual assessment. However they should be ok together. There is one possible interaction. Methadone may reduce the metabolism of Cymbalta (duloxetine) (meaning that for the same dose your blood levels may be higher than they would ordinarily be). This may mean a dose adjustment. ...Read more

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How does someone wean herself off 30 mg cymbalta (duloxetine) safely?

Weaning self fr cymb: Very easy, if this medication was prescribed by u physician to him. ...Read more

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Is it dangerous to mix flexeril, cymbalta, lyrica, (pregabalin) mobic, hyzaar all together? I am currently taking these every night?

Is it dangerous to mix flexeril, cymbalta, lyrica, (pregabalin) mobic, hyzaar all together? I am currently taking these every night?

Possibly: Depending on dose, this combination could result in increased bleeding tendency, and serotonin syndrome, which is characterized by high fever, muscle aches, etc. Be sure your doctor knows what and how much you are taking. ...Read more

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Before changing meds dr. Wants to try 90 cymbalta (duloxetine) -is that safe or to toxic on liver?

Before changing meds dr. Wants to try 90 cymbalta (duloxetine) -is that safe or to toxic on liver?

Cymbalta (duloxetine): 90 mg of Cymbalta (duloxetine) is a common and safe dose. Many people are actually treated with 120 mg of Cymbalta (duloxetine) per day. ...Read more

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Possible side effect to cymbalta (duloxetine)?

Possible side effect to cymbalta (duloxetine)?

G.I. symptoms.: The most common side effects of Cymbalta (duloxetine) are nausea, dry mouth, constipation, sleep change, diarrhea, appetite change, fatigue, dizziness, vomiting, and increased sweating. However, because of the uniqueness of your chemistry, anything can be a side effect. ...Read more

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What are some of the commone side effects of cymbalta (duloxetine)?

What are some of the commone side effects of cymbalta (duloxetine)?

Varied Side Effects: The most commonly observed side effects in cymbalta-treated patients (incidence of at least 5% and at least twice the incidence in placebo patients) were nausea, dry mouth, somnolence, fatigue, constipation, decreased appetite, and hyperhidrosis (excessive sweating). Many of these side effects are short lived as the body adapts to the medication. ...Read more

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How much time does it take a cymbalta (duloxetine) pill to work out of my system?

How much time does it take a cymbalta (duloxetine) pill to work out of my system?

Few weeks: If you have been on cymbalta (duloxetine) for more than a few weeks then it will take a few weeks to 'wash out' of your body. This is not the type of drug that you should arbitrarily, without your doctor's advice.
If it's only 1 pill- no time at all ...Read more

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What are the symptoms of quitting cymbalta (duloxetine) and how long should they last?

What are the symptoms of quitting cymbalta (duloxetine) and how long should they last?

Return of symptoms!: I agree that you can experience serotonin discontinuation syndrome when stopping cymbalta, (duloxetine) which can feel like having the flu and sometimes strange sensations as well. As a result it should be tapered if possible with the help of your provider. This is pretty rare with Cymbalta (duloxetine) however; of greater concern is the possibility that your symptoms could recur, you should discuss this with your doc also. ...Read more

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I had the worst headache of my life last night, so I took some cymbalta (duloxetine) and tramadol within 2 hours of each other, is there something I should do now?

I had the worst headache of my life last night, so I took some cymbalta (duloxetine) and tramadol within 2 hours of each other, is there something I should do now?

Cephalagia: The worst headache could be a medical emergency. There are several possibilities. You don't say how it is now. I would consider urgent evaluation by your md or er. Neurological problems may be persistent. That kind of headache shouldn't be managed by self treatment unless you know precisely what is going on. Even then, get seen. ...Read more

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How can I solve my stomach aches and frequent urinating problems when cymbalta (duloxetine) wears off?

How can I solve my stomach aches and frequent urinating problems when cymbalta (duloxetine) wears off?

Taper slowly.: Your question is not clear. If you are stopping Cymbalta (duloxetine) and have these problems then a long slow taper over 4-6 weeks is necessary for some folks.
If you are taking the medication regularly tehn the half-life of the medication is long enough not to be the cause and further evaluation needs to be undertaken. ...Read more

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Is the butrans patch good for fibro and what can I take for upper resp/sinus infec. That will not interact with cymbalta (duloxetine)...

Is the butrans patch good for fibro and what can I take for upper resp/sinus infec. That will not interact with cymbalta (duloxetine)...

Beware: I would strongly encourage you to consider an alternative form of pain medication besides Butrans as opioid medications should be a last resort due to all the adverse effects that come along with using them. Some basic things that really don't interact with anything would be steam treatments and saline nasal irrigations. Otherwise to suggest meds, it helps to know your most bothersome symptoms. ...Read more

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There any interaction between cymbalta (duloxetine) buspae Risperdal wellbutreinxl?

There any interaction between cymbalta (duloxetine) buspae Risperdal wellbutreinxl?

Too many meds: Taking all of these medications together is not a good idea. You run the risk of serotonin syndrome, a potentially lethal condition and you are at increased risk of seizures. It sounds like you must have a difficult case of depression and anxiety and I suggest you talk with you doctor about a better combination. Cymbalta (duloxetine) and Wellbutrin are both antidepressants and you should be on one or the other ...Read more

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Could the combination of cymbalta (duloxetine) and wellbutrin have worked/not worked for some people?

Could the combination of cymbalta (duloxetine) and wellbutrin have worked/not worked for some people?

Yes: Cymbalta (duloxetine) and Wellbutrin are potent anti-depressants. They are not usually prescribed together unless it is a severe case of depression. Anti-depressants can work or fail solo or in combination. There is no wrong answer, the only way to know if they will work is to try them. ...Read more

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I was told many years ago that I have fibromyalgia. Have been given cymbalta, it makes me very sick. Also tried lyrica (pregabalin) it made me a zombie. What can

I was told many years ago that I have fibromyalgia. Have been given cymbalta, it makes me very sick. Also tried lyrica (pregabalin) it made me a zombie. What can

Many choices.: Assume you are already doing the non pharmacologic approaches. Savella (milnacipran) and Gabapentin are the other medications approved for fm. There are many non approved meds routinely tried for fm such as the tca's (amitriptylline, nortriptylline, etc.), venlafaxine, cyclobenzaprine, analgesics and non steroidal anti inflammatory meds. ...Read more

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How does cymbalta (duloxetine) work?

How does cymbalta (duloxetine) work?

Cymbalta (duloxetine): Is an nsri, or a norepinephrine/serotonin reuptake inhibitor. This means that Cymbalta (duloxetine) slows the breakdown of both of these neurotransmitters, which allows them to have a longer effect. ...Read more