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Doctor insights on: Cyclical Cushing's Syndrome

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What is Cushing syndrome?

What is Cushing syndrome?

Cushing syndrome: read this: http://en.wikipedia.org/wiki/Cushing%27s_syndrome

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What is cushing's syndrome?

What is cushing's syndrome?

Symptom / sign mix: The familiar physical changes from excess glucocorticoids from any cause, made in the body or prescribged. Red, swollen face, hypertension, glucose intolerance, truncal obesity, fat pad on back of neck, fragile skin, likelihood to get infections, mood problems, acne, more. Contrast "cushing's disease" in which these by definition result from a pituitary adenoma making acth. ...Read more

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Is polycystic ovary disease a syndrome?

Is polycystic ovary disease a syndrome?

Yes: Pcos is also called stein leventhal syndrome. Strangely, you don;t have to have ovarian cysts to have this disease. Symptoms include lots of things including acne, excessive hair growth, obesity and infertility. ...Read more

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What is antiphospolipid syndrome (hughes syndrome)?

What is antiphospolipid syndrome (hughes syndrome)?

Antiphospholipids: An autoimune disorder characterized by antibodies to certain phopholipids that predisposes to clotting problmes and pregnancy complications. A certain percentage will develop into systemic lupus. ...Read more

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What is premenstrual syndrome?

What is premenstrual syndrome?

Emotional disturbanc: The specific emotional and physical symptoms attributable to premenstrual syndrome or PMS vary from woman to woman, but each individual woman's pattern of symptoms is predictable, occurs consistently during the ten days prior to menses, and vanishes either shortly before or shortly after the start of menstrual flow. In particular, emotional symptoms must be present consistently to diagnose pms. ...Read more

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What is polycystic ovarian syndrome?

What is polycystic ovarian syndrome?

Hormone imbalance: Pcos is an imbalance in hormones that can cause irregular periods, acne, excess hair, and infertility. Blood tests can determine if your pcos is from an imbalance in pituitary hormones (lh & fsh), adrenal hormones (dheas), or Insulin resistance. Some doctors recommend a pelvic ultrasound to assess the ovaries to look for cysts. ...Read more

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Is XXY klinefelter's syndrome related at all to marfan's syndrome?

Is XXY klinefelter's syndrome related at all to marfan's syndrome?

No: The two syndromes have some similar features, but they are different syndromes that are unrelated. Klinefelter syndrome is caused by ahaving at least one extra x chromosome in a person who has a y chromosome (normal male=46 xy, klinefelter=47xxy). Typical marfan syndrome is caused by a mutation in fbn1, coding for fibrillin-1. ...Read more

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Why there's hirsutism in cushing's syndrome?

Why there's hirsutism in cushing's syndrome?

Adrenal androgens: When the adrenals are stimulated, they make cortisol, but also androgens, like DHEA-S, which causes hirsutism in women. ...Read more

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Is premenstrual syndrome an illness?

Is premenstrual syndrome an illness?

PMS/PMDD: 90% of women will experience some combination of premenstrual symptoms, called premenstrual moliminia. 20% of women will have 'distressing symptoms'. Using strict guidelines, 3-8% of women have a constellation of symptoms, some disabling, and are diagnosed with pmdd. Both PMS and pmdd are conditions for which there is treatment. ...Read more

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What is polycystic ovarian syndrome (pcos)?

What is polycystic ovarian syndrome (pcos)?

Dx of exclusion: Pcos is a DX of exclusion where a female has hyperandrogenism and oligo/amenorrhea in the absence of another endocrine disorder like androgen secreting tumor, cushing's syndrome, cah, etc. Most females are Insulin resistant as well. Depending on which criteria you look at, ovarian cysts don't necessarily have to be part of the diagnosis. Pcos is a very old term and somewhat outdated. ...Read more

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Is polycystic ovary syndrome treatable?

Is polycystic ovary syndrome treatable?

Somewhat: Hi. Standard treatments for PCOS include BCPs with a low-androgenic progestin, metformin, and spironolactone in various combinations. PCOS increases type 2 diabetes risk, and metformin helps with that too. When fertility is desired, in addition to stopping BCPs, an agent such as clomiphene may be needed as well. As the underlying cause(s) is/are incompletely understood, we still have a way to go. ...Read more

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Is it normal to have premenstrual syndrome followed by postmenstrual syndrome?

Is it normal to have premenstrual syndrome followed by postmenstrual syndrome?

Postmenstrual? : Do you mean after your period, or after your menopause? If you're having after menses mood problems, you may in fact have depression or another disorder. See your doctor for further elucidation of the problem. ...Read more

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What is klienfelter (xxy) syndrome?

What is klienfelter (xxy) syndrome?

XXY: The klinefelter has a pattern of the sex chromosomes as XXY ( with male features). The extra x comes from an egg that had 2 x's at conception when the male y was added.The resulting fetus with 47 chromosomes is compatible with life.The baby will grow up with male sex characteristics, but often a short penis and sterility by adolescence along with other issues. ...Read more

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What is klienfelter (xxy) syndrome?

What is klienfelter (xxy) syndrome?

XXY: The klinefelter has a pattern of the sex chromosomes as XXY ( with male features). The extra x comes from an egg that had 2 x's at conception when the male y was added.The resulting fetus with 47 chromosomes is compatible with life.The baby will grow up with male sex characteristics, but often a short penis and sterility by adolescence along with other issues. ...Read more

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What is polycystic ovary syndrome?

What is polycystic ovary syndrome?

Mixed bag: Pcos is a constellation of findings which includes irregular periods, elevated testosterone or testosterone like hormones (with no other cause), resistance to Insulin (predisposition to type 2 diabetes), problems with lipids, many times unwanted face and body hair, sometimes scalp hair loss. Ovarian cysts may or may not be found. Pcos is an outdated term but no better one has been agreed upon. ...Read more

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What is may-turner syndrome?

What is may-turner syndrome?

Compressed iliac vei: May- thurner syndrome classically refer to a compression of the left common iliac vein by the iliac artery . This result in left leg pain, swelling and deep vein thrombosis. It has now been expanded and is now called non thrombotic iliac vein lesions (nivl), to include both the right and left iliac veins.). ...Read more

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What is cushing's syndrome and it affect?

What is cushing's syndrome and it affect?

Hormonal...: It is hormonal problem where the body experiences changes due to too much glucocorticoids which might be elevated for different reasons like for example adrenal tumors( usually benign), medications, other hormonal issues. Symptoms can be weight gain, elevated blood sugar, fatigue, muscle weakness, moon face, among others. ...Read more

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Why is cushing's disease or syndrome fatal?

Excess cortisol: Cushing's disease is excessive cortisol in the body from a pituitary tumor that leads to its secretion.Cushing's syndrome refers to the stigmata with excessive cortisol.This can be from the pituitary or administered by drs. Symptoms include hypertension, obesity, heart problems, sensitivity to infection. Cushing's disease/syndrome can be treated so it is not necessarily fatal, but it can be. ...Read more

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What exactly is polycystic ovarian syndrome like?

What exactly is polycystic ovarian syndrome like?

Insulin and ovaries: Pcos is a manifestation of Insulin resistance, which indicates pre-diabetes or diabetes 2.There are many derangments including those of adrenal androgen, a higher free testosterone, eradication of/or irregular cycles.Hirsuitism and acne increase with these androgens. A woman's cycle becomes annovulatory. Glucophage (metformin) is the preferred treatment of the problem. Clomiphene is used to help ovulation. ...Read more

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My lover has just been diagnosed with cushing’s syndrome. I am worried but she acts like it is not a problem. Who can tell me what it means?

My lover has just been diagnosed with cushing’s syndrome. I am worried but she acts like it is not a problem. Who can tell me what it means?

Too much cortisol: Cushing's syndrome means the body has too much cortisol in it. This can lead to high blood pressure, diabetes, osteoporosis. It can be caused by medications like Prednisone (most common cause - doesn't need treatment, but should try to minimize steroid dose), or by a cortisol producing tumor (needs surgery) or a certain type of pituitary tumor (called cushing's disease - also needs surgery). ...Read more

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What are the advantages and disadvantages of different treatments for cushing’s syndrome?

What are the advantages and disadvantages of different treatments for cushing’s syndrome?

Depends: The treatment options depend on the cause of the cushing's syndrome. If the cause is due to overuse of steroids, then the treatment is to lower the dose. This is the best case scenario. Other treatment options involve: surgery (pros: cure possible, cons: surgery +/- complications), radiation therapy (cons: side effects), medications (cons: usually not a cure, side effects from med)... ...Read more

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What is cushing's syndrome?

Symptom / sign mix: The familiar physical changes from excess glucocorticoids from any cause, made in the body or prescribged. Red, swollen face, hypertension, glucose intolerance, truncal obesity, fat pad on back of neck, fragile skin, likelihood to get infections, mood problems, acne, more. Contrast "cushing's disease" in which these by definition result from a pituitary adenoma making acth. ...Read more

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Is cushing's syndrome easy to diagnose?

Is cushing's syndrome easy to diagnose?

No, it's a tough one: Cushing's syndrome is a condition where your body makes too much cortisol (a hormone). A blood draw, 24 hour urine measurement of cortisol, midnight salivary cortisol measurement or a test called dexamathasone suppression test can be done to give you the diagnosis. Often time, you'll need multiple or all of the tests above to make an accurate diagnosis. It's one of the hardest diagnosis to make. ...Read more

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What is cushing's syndrome and it affect?

Hormonal...: It is hormonal problem where the body experiences changes due to too much glucocorticoids which might be elevated for different reasons like for example adrenal tumors( usually benign), medications, other hormonal issues. Symptoms can be weight gain, elevated blood sugar, fatigue, muscle weakness, moon face, among others. ...Read more

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What are the tests for cushing's syndrome?

What are the tests for cushing's syndrome?

CUSHING'S SYNDROME: Dx: 1. Urinary free cortisol - 4 x upper limit of normal. 2. Dexamethasone test- plasma cortosol level elevated.3. Acth level is elevated in pituitary cause. ...Read more

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What are the symptoms of cushing's syndrome?

What are the symptoms of cushing's syndrome?

Cushings varies: The symptoms of Cushing's disease vary, but they can include weight gain, increased blood pressure, a round-shaped face, headaches, mood changes, altered menses, hair growth, the formation of a lump at the top of the back, and fatigue / tiredness. ...Read more

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What are the symptoms of cushing's syndrome?

Many: The signs and symptoms of cushing's syndrome vary. Common signs and symptoms involve progressive obesity and skin changes, such as: weight gain and fatty tissue deposits, particularly around the midsection and upper back, in the face (moon face) and between the shoulders (buffalo hump) pink or purple stretch marks (striae) on the skin of the abdomen, thighs, breasts and arms thinnin. ...Read more

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What kind of condition is cushing's syndrome?

What kind of condition is cushing's syndrome?

Cushing's syndrome: Cushing's syndrome is a condition where your body makes too much cortisol (a hormone). A blood draw, 24 hour urine measurement of cortisol, midnight salivary cortisol measurement or a test called dexamathasone suppression test can be done to give you the diagnosis. Often time, you need multiple or all of the tests above to make an accurate diagnosis. ...Read more

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How do you know if someone has cushing's syndrome?

Many symptoms: Symptoms / signs: truncal obesity (mr. Potatohead look), "moon" facies, thinning of skin, easy bruising, "buffalo" hump in upper back, purple stretch marks, hypertension, fatigue, psychiatric sx, insomnia, excess hair growth, muscle weakness and loss. Symptoms are often progressive and should prompt screening. ...Read more

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What age group is most prone to having cushing's syndrome?

What age group is most prone to having cushing's syndrome?

Cushing's: What makes you ask that question? Family history? Cushing's syndrome can occur in any age group. If you have symptoms you should see your doctor. Additionally you can go on the web and find many articles/comments about Cushing's syndrome. ...Read more

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What kind of symptoms do cushing's syndrome people usually get?

Many: Facial plethora, acne, hypertension, weight gain, swelling, violaceous streaks, easy bruising, proximal muscle weakness, diabetes, central fat accumulation, elevated cholesterol, osteoporosis - all are manifestations of cushing's syndrome. The severity of symptoms and signs will reflect the duration and severity of steroid excess. ...Read more

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What are the signs that you see when you have cushing's syndrome?

Many features: Cushing's is a rare condition, but important to recognize since it can often be cured. There is abdominal (central) obesity (buffalo hump) often with diabetes and hypertension, but also thin skin (bruising, purple striae), rapid change in appearance, muscle weakness, maybe hirsutism, cognitive difficulties. See your doctor. ...Read more

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Can one have cushing's syndrome for the past 10years and not know about it?

Can one have cushing's syndrome for the past 10years and not know about it?

Cushing's unknow 10y: Yes Cushing's can be a slow developing problem. The only way to know is to be tested for it. I always recommend a 24 hr urine for urinary free cortisol AND and overnight Dexamethasone suppression testing. It can be a difficult Dx to make early in the evolution of Cushing's. Would be happy to get more details with a second opinion. ...Read more

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Did anyone been diagnosed with cushing's syndrome but there tests didn't show it the first time or what?

Did anyone been diagnosed with cushing's syndrome but there tests didn't show it the first time or what?

Cushing's diagnosis: The diagnosis of cushing's can be subtle and complicated. The presence of a nodule or a tumor does not establish the diagnosis. The biochemical tests (blood, urine) can be difficult to interpret, since we all make cortisol. If there is a question, make sure you are seeing an endocrinologist. ...Read more

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Is it possible to be diagnosed with cushing's syndrome but there tests didn't show it the first time or what?

Is it possible to be diagnosed with cushing's syndrome but there tests didn't show it the first time or what?

Difficult diagnosis: Hi. Yes, Cushing's can be one of the more difficult and subtle diagnoses in all of endocrinology because of fluctuations in adrenal function throughout the 24-hour period. I see you're in my town. I probably know who diagnosed you, if it's an endocrinologist! Proceed with the work up. Assuming the diagnosis is correct, you don't want to leave it untreated. Good luck! ...Read more

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Can one have cushing's syndrome for the past 10years and not know about it? Would the symptoms be mild/slowly progressing all the while?

Can one have cushing's syndrome for the past 10years and not know about it? Would the symptoms be mild/slowly progressing all the while?

Cushing's: Sometimes Cushing's comes on fast, but sometimes it can be present for years before it is diagnosed. The symptoms of Cushings, central obesity, diabetes, hypertension, are very common. Raising suspicion for Cushings is abdominal striae, bruising, hirsutism, low potassium, rapid onset, and others. The screening tests for Cushings are fairly easy to do. ...Read more

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What is Cushing syndrome?

Cushing syndrome: read this: http://en.wikipedia.org/wiki/Cushing%27s_syndrome

Get a more detailed answer ›