Doctor insights on:
Cutaneous T Cell Lymphoma In Children
Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?
Not Completely: The average number of biopsies to completely diagnose CTCL is about 6. That said, if the type of CTCL is the common type, mycosis fungoides(MF), and not mimics of MF, then 1 or 2 biopsies could be diagnostic especially if typical patches, plaques of CTCL. If the latter, ancillary tests including molecular clonality T cell test are crucial for diagnosis excluding mimics. Rebiopsy in about 3 mos. ...Read moreSee 1 more doctor answer
Skin is the largest and one of most complex organs of body. 3 layers: epidermis (outer), dermis (main part) and subcutaneous layers covers entire body, contains many specialized cells, maintains body temp, gathers sensory info from the outer world, has extremely important immune functions. It can give crucial clues as to what is internal. Dermatology and plastic surgery are ...Read more
Type of NHL: Cutaneous t cell lymphoma (ctcl) is a type of non-hodgkin's lymphoma(nhl) , which is a type of cancer of the immune system. Unlike most nhl (which are generally b-cell related), ctcl is caused by a mutation of t cells. The malignant t cells in the body initially migrate to the skin, causing various lesions to appear- reference wikipedia and cancer.Gov. Best wishes. ...Read moreSee 2 more doctor answers
Multiple fashions: It varies by stage (spread). It can be treated via chemotherapy or radiation therapy. Some use total skin radiation in some cases. In my practice, even when widespread and felt to be "incurable" focal radiation a small number of worst problemsites (say 2 or 3) can make it a long term issue when other methods of treatment fail. It is best to find a team of local md's who treat it often. ...Read more
Not exactly...: Cutaneous t cell lymphoma (ctcl) is a disorder of a type of immune cell, the t cell. Hodgkin's disease is a cancer of b cells, another type of immune cell. Thus ctcl is technically a non-hodgkin's lymphoma. However, people typically use 'non-hodgkin's lymphoma' to describe other types of b cell cancers that do not fit the characteristics of hodgkin's disease. Talk with your doctor for more info. ...Read moreSee 1 more doctor answer
Diagnosed 3 years ago with cutaneous t-cell lymphoma. Within the past two months i've had a couple of spells of dizziness and some steady pain in my right shoulder blade. Concerned cancer has spread?
Upper arms feel warm to touch, no allergies, past 4 days. What can cause this ? Also have been diagnosed with cutaneous T cell lymphoma.
Uncertain but need e: You need to see your oncologist to be certain there is no relationship.As you are immunodeficient -we are concerned about infection. ...Read more
Many types : There are many types of t cell lymphoma. Some types are very slow growing, treatable but not curable..Patients can live for decades. Other types are much more aggressive. Some are highly treatable and even can be cured while others are quite difficult to get into remission. ...Read moreSee 1 more doctor answer
T-cell NHL: The prognosis for t-cell non-hodgkin's lymphoma (nhl) vs. B-cell nhl depends on multiple factors, but in general t-cell nhl has a worse prognosis. One reason is that b-cell, cd20+ nhl can be treated with the anti-cd20 monoclonal antibody Rituximab in addition to chemotherapy. We currently don't have such an effective, low toxicity antibody (biologic treatment) for t-cell nhl. ...Read moreSee 2 more doctor answers
Not really: Non-hodgkin's lymphomas are a very large group of diseases. Lymph cell can be called t cells or b cells based on surface proteins. T cell lymphomas are just one group of non-hodgkins lymphomas. There are also several types of those tcell lymphomas. ...Read more
A Rare Lymphoma: Hstcl is a rare cancer of the the white blood cells. It usually affects young men with a history of immunosuppression for other diseases like inflammatory bowel disease (uc and/or crohn's) or after an organ transplant. The bad cells usually grow in the liver, spleen and bone marrow. It is treated with chemotherapy and possibly a bone marrow transplant. It unfortunately can be difficult to cure. ...Read more
What is the relationship of hepatosplenic t-cell lymphoma and low lymphocyte levels in the blood?
NK/T cell NHL: The treatment is largely determined by the extent of disease. Patients with localized stage, therapy would be combined radiation and chemotherapy. Patients with disseminated lymphoma, combination chemo would be recommended.. For most patients who achieve a partial response after induction therapy , a bone marrow transplant as consolidation would be recommended. Discuss with your oncologist. ...Read more
Skin biopsy for some reason tested cd3 but was neg does that ensure no t cell lymphoma or it could still be developing?
Yiour doctor/oncolog: Only your treating doctor can help explain what is going on. Please ask him/her to explain and get your answers from the person putting you thru the biopsies etc. It does not sound anything meaningful to me. ...Read more
Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?
Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more
Have itchy skin. 2 biopsies with lymphocyte infiltrate no T cell lymphoma. Ana was 640. Could it be autoamune. Have Hypothyroid.
It could be: If your hypothyroidism is related to an autoimmune disorder, then your skin problem may be as well - guilty by association. Make sure that you have not become allergic to one of the medications you have been taking. There are several options on treatment and I suggest that you consult a dermatologist, a 2nd opinion if needed. ...Read more
Is angioimmunoblastic t-cell lymphoma still treatable if in the marrow, anemia, low platelets, swelling?
T cell lymphoma: It is treatable but need careful supervision under the oncologist as chemo can be detrimental with low blood counts but sometimes that is the only way marrow can be cleared of lymphoma so lot of thinking needs to be done in selecting appropriate chemo for such patients. ...Read moreSee 1 more doctor answer
I had t-cell lymphoma 3 times about 10 to 7 years ago, then breast cancer, did chemo and radi. And now, I have cracks in teeth is this normal?
Long term effects: Yes chemotherapy & radiotherapy will cause short term and long term damage to teeth along with gums . Yours could be long ted effects , causing cracks including loss of enamel .Good you won the battle 4 times , think it as battle scars , visit your dentist to save them . Good luck. ...Read moreSee 1 more doctor answer
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