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Doctor insights on: Cutaneous T Cell Lymphoma

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Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?

Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?

Not Completely: The average number of biopsies to completely diagnose CTCL is about 6. That said, if the type of CTCL is the common type, mycosis fungoides(MF), and not mimics of MF, then 1 or 2 biopsies could be diagnostic especially if typical patches, plaques of CTCL. If the latter, ancillary tests including molecular clonality T cell test are crucial for diagnosis excluding mimics. Rebiopsy in about 3 mos. ...Read more

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Cutaneous (Definition)

Skin is the largest and one of most complex organs of body. 3 layers: epidermis (outer), dermis (main part) and subcutaneous layers covers entire body, contains many specialized cells, maintains body temp, gathers sensory info from the outer world, has extremely important immune functions. It can give crucial clues as to what is internal. Dermatology and plastic surgery are ...Read more


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Most common symptoms of cutaneous t cell lymphoma?

Most common symptoms of cutaneous t cell lymphoma?

Itchy skin: Pruritus /itchy skin would be the most common symptoms. Skin manifestation can vary from redness, dryness, lumps, etc. ...Read more

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Living with Sickle Cell Disease (Checklist)

Keep doctor's appointments
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Keep oxygen up by maintaining low weight, no smoking
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What is cutaneous t-cell lymphoma exactly?

What is cutaneous t-cell lymphoma exactly?

Type of NHL: Cutaneous t cell lymphoma (ctcl) is a type of non-hodgkin's lymphoma(nhl) , which is a type of cancer of the immune system. Unlike most nhl (which are generally b-cell related), ctcl is caused by a mutation of t cells. The malignant t cells in the body initially migrate to the skin, causing various lesions to appear- reference wikipedia and cancer.Gov. Best wishes. ...Read more

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How can cutaneous t cell lymphoma be treated?

Multiple fashions: It varies by stage (spread). It can be treated via chemotherapy or radiation therapy. Some use total skin radiation in some cases. In my practice, even when widespread and felt to be "incurable" focal radiation a small number of worst problemsites (say 2 or 3) can make it a long term issue when other methods of treatment fail. It is best to find a team of local md's who treat it often. ...Read more

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Most common symptoms of cutaneous t cell lymphoma?

Itchy skin: Pruritus /itchy skin would be the most common symptoms. Skin manifestation can vary from redness, dryness, lumps, etc. ...Read more

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Is cutaneous t-cell lymphoma the same as non-hodgkin's lymphoma?

Is cutaneous t-cell lymphoma the same as non-hodgkin's lymphoma?

Not exactly...: Cutaneous t cell lymphoma (ctcl) is a disorder of a type of immune cell, the t cell. Hodgkin's disease is a cancer of b cells, another type of immune cell. Thus ctcl is technically a non-hodgkin's lymphoma. However, people typically use 'non-hodgkin's lymphoma' to describe other types of b cell cancers that do not fit the characteristics of hodgkin's disease. Talk with your doctor for more info. ...Read more

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Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?

Not Completely: The average number of biopsies to completely diagnose CTCL is about 6. That said, if the type of CTCL is the common type, mycosis fungoides(MF), and not mimics of MF, then 1 or 2 biopsies could be diagnostic especially if typical patches, plaques of CTCL. If the latter, ancillary tests including molecular clonality T cell test are crucial for diagnosis excluding mimics. Rebiopsy in about 3 mos. ...Read more

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Dr. Michael Thompson
1,724 doctors shared insights

Lymphoma (Definition)

Lymphoma is cancer of the lymph system, which is an infection fighting collection of nodes of lymph tissue populated by white blood cells and ducts that drain excess fluid. The system ...Read more