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Doctor insights on: Cushings Desiese

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What's cushings disease?

What's cushings disease?

ACTH from pituitary: By definition this is caused by an acth-producing tumor that causes the adrenal glands to overproduce cortisol. Any cause of too much cortisol or some other substance with cortisol-like activity will produce obesity, hypertension, glucose intolerance / high blood sugar, mood changes, immune compromise, and red face (c's syndrome). This is always serious and you need a skilled physician. Good luck. ...Read more

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Will T3 (liothyronine) cure adrenal insufficiency?

Will T3 (liothyronine) cure adrenal insufficiency?

No: Adrenal insufficiency is the result of the failure of the adrenal glands to make cortisol. T3 (liothyronine) will not treat adrenal insufficiency because it is a thyroid hormone. ...Read more

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Why's addison's disease so rare?

Why's addison's disease so rare?

Life threatening: We're lucky it is uncommon, because untreated addison's disease can be fatal. Most addison's in developed countries is autoimmune, and sometimes associated with other autoimmune diseases (eg. Hashimoto's, type 1 diabetes, etc). ...Read more

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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

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Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Maybe: Hydroxylase deficiency is actually a continuum, and there are many alleles. A workup is probably not worthwhile. Manage unwanted body hair with electrolysis or lasers -- you're doing yourself a favor. If your urinalysis (chemical, sediment), renal functions (BUN, creatinine) and concentrating ability (SG >1.020) while thirsty) are normal, I would not recommend further studies. ...Read more

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Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

No: Spot "basal cortisol" levels mean nothing except in context. They help rule some things in and some things out. The highest basal cortisol levels have been found in soldiers in the battlefield and medical students in exams. Ignore all "pop" sites relating to pituitary / adrenal disease and remember that reference ranges are set so that many healthies fall outside on either end. ...Read more

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What does congenital adrenal hyperplasia cah look like?

What does  congenital adrenal hyperplasia cah look like?

Virilization: In the classic form newborn girls will often have ambiguous looking genitalia because of intrauterine exposure to their own overproduction of androgens. Can't really see it in a newborn boy. In non-classical early pubic hair in both sexes can be presenting feature. As kids grow older other things may warrant checking like recalcitrant acne (both sexes) or irregular periods/hirsutism in girls. ...Read more

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How do you diagnose adrenal fatigue / hypoadrenia?

How do you diagnose adrenal fatigue / hypoadrenia?

See a medical doctor: These terms are not true medical conditions, they are marketing terms used by 'alternative' medical practitioners, usually to convince you to purchase unnecessary medical tests and treatments which do little for you. Adrenal insufficiency is the correct medical term for underactive adrenals, and specific testing should be arranged by your doctor if that diagnosis is being considered. ...Read more

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How do physicians diagnose cushing's disease?

How do physicians diagnose cushing's disease?

Labs and imaging: A lab draw or urine test can tell if your body is making too much cortisol. This is a condition called cushing's syndrome. Cushing's disease is cushing's syndrome caused by a pituitary tumor. Imaging studies (MRI) can locate this tumor. ...Read more

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Do women with addison's disease/adrenal insufficiency also suffer from low estrogen ?

Do women with addison's disease/adrenal insufficiency also suffer from low estrogen ?

Not necessarily : If you are a post menopausal female your adrenal glands are providing your only source of estrogen. So if you have low adrenal function you could most certainly have low estrogen. However, you may also then have other low hormone levels like Progesterone and testosterone. The truth is most women do not suffer from low estrogen, you need very little but they frequently suffer from low progesterone. ...Read more

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Please explain "corticoid axis disturbance" I am being tested for cushing's disease. ?

Cortisone: For practical purposes, the term describes a problem with the regulation of cortisone production. Cortisone is produced in the adrenal glands. This production is closely regulated by the thalamus and pituitary gland. A tumor in the pituitary region may disturb the production of cortisone or trigger increased production. ...Read more

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Do women with addison's adrenal insufficiency have low estrogen ?

Not significantly: The adrenal glands produce hormones which are precursors to estrogen, but that only comprises a small amount relative to what the ovaries make. Ovaries are the source of most estrogen in females. If menstrual cycles are irregular in properly treated addison's disease, autoimmune disease of the ovaries may need to be considered also. ...Read more

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How can we fix adrenal insufficiency naturally?What are the typical symptoms of it?Can armor thyroid reveal adrenal insufficiency?

Depends on the cause: There are several conditions which can cause adrenal insufficiency. Treatment includes treating the cause in addition to steroid replacement. I am not aware of natural way of treating insufficiency. ...Read more

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Ds le cas du carence de Ca ds les cellules ces dernieres seront moins sensibles aux hormones thyroidiens malgre taux normal de t3, (liothyronine)t4.c'est vrai?

Ds le cas du carence de Ca ds les cellules ces dernieres seront moins sensibles aux hormones thyroidiens malgre taux normal de t3, (liothyronine)t4.c'est vrai?

Je ne suit certain: quois que vous me demandez. C'est possible d'avoir Cancer tyrioidiens avec les hormones normales a la meme fois. Ils sont désordres différentes qui existe dans le meme organe. J'espère que ca vous aide. Dr. Anne ...Read more

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What autoimmune disease causes hyperandrogenic symptom like irreg cycles, hirsutism, acne, hair loss, cushing is ruled out, mpv high, hormones normal?

What autoimmune disease causes hyperandrogenic symptom like irreg cycles, hirsutism, acne, hair loss, cushing is ruled out, mpv high, hormones normal?

See below: Usually autoimmune disease will not cause hair growth instead you would have hair loss. On first glance your condition seems suggestive for pcos or polycystic ovarian syndrome. Talk to your doctor to see if they checked you for this. ...Read more

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Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106. Hysterectomy, thyromegaly Will metformin reduce testosterone?

Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106.   Hysterectomy, thyromegaly
Will metformin reduce testosterone?

Hormones: Metformin medicine that keeps your blood sugar under control should not have an effect on testosterone. That said, too much metformin will likely lower your testosterone. Are you checking your blood sugar regularly? Please let me know how things are going. ...Read more